SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bx0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		5 / 12 LEU A 200
GLY A 173
CYH A 114
ALA A 175
ALA A  98
 None
None
None
FAD  A 315 ( 4.0A)
None
 1.08A 2br4A-1bx0A:
3.7		 2br4A-1bx0A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		5 / 12 LEU A 200
GLY A 173
CYH A 114
ALA A 175
ALA A  98
 None
None
None
FAD  A 315 ( 4.0A)
None
 1.17A 2br4D-1bx0A:
3.0		 2br4D-1bx0A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1290_1
(FICOLIN-2)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		5 / 9 SER A 234
VAL A 233
SER A 209
SER A 208
ASP A  52
 PO4  A 316 (-3.1A)
None
None
None
None
 1.09A 2j2pD-1bx0A:
0.0
2j2pE-1bx0A:
0.0		 2j2pD-1bx0A:
20.50
2j2pE-1bx0A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_2
(MINERALOCORTICOID
RECEPTOR)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		4 / 4 LEU A 197
LEU A 200
MET A 261
MET A 251
 None
 1.31A 2oaxB-1bx0A:
0.0		 2oaxB-1bx0A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		5 / 12 ILE A 174
LEU A 200
GLY A 203
SER A 234
GLN A 237
 None
None
None
PO4  A 316 (-3.1A)
None
 1.11A 2ogyB-1bx0A:
undetectable		 2ogyB-1bx0A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		5 / 9 LEU A 211
ILE A 174
GLY A 173
GLY A 273
SER A 209
 None
 1.16A 2qmmA-1bx0A:
3.0		 2qmmA-1bx0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		5 / 12 ILE A 174
LEU A 200
GLY A 203
SER A 234
GLN A 237
 None
None
None
PO4  A 316 (-3.1A)
None
 1.15A 2ycjA-1bx0A:
undetectable		 2ycjA-1bx0A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		6 / 10 LEU A 202
ILE A 247
ILE A 174
GLY A 173
GLY A 273
PHE A 231
 None
 1.23A 4fakA-1bx0A:
1.1		 4fakA-1bx0A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		5 / 9 PHE A  62
LEU A 147
LEU A 136
PHE A 135
ASP A  81
 None
 1.20A 4qopA-1bx0A:
0.3		 4qopA-1bx0A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_B_HQEB503_1
(CATALASE)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		5 / 9 PHE A  62
LEU A 147
LEU A 136
PHE A 135
ASP A  81
 None
 1.21A 4qopB-1bx0A:
0.2		 4qopB-1bx0A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		4 / 8 PHE A  62
LEU A 147
LEU A 136
PHE A 135
 None
 0.93A 4qopC-1bx0A:
0.3		 4qopC-1bx0A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		3 / 3 ILE A 166
ILE A 281
MET A 261
 None
 0.69A 5i9yA-1bx0A:
undetectable		 5i9yA-1bx0A:
23.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		7 / 9 SER A  96
THR A 172
GLY A 173
ALA A 175
CYH A 272
GLY A 273
LEU A 274
 FAD  A 315 (-3.7A)
FAD  A 315 (-3.4A)
None
FAD  A 315 ( 4.0A)
None
None
None
 0.72A 5vw4A-1bx0A:
40.7		 5vw4A-1bx0A:
48.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		6 / 8 SER A  96
THR A 172
GLY A 173
CYH A 272
GLY A 273
LEU A 274
 FAD  A 315 (-3.7A)
FAD  A 315 (-3.4A)
None
None
None
None
 0.61A 5vw5A-1bx0A:
40.8		 5vw5A-1bx0A:
48.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		6 / 8 SER A  96
THR A 172
GLY A 173
ALA A 175
CYH A 272
GLY A 273
 FAD  A 315 (-3.7A)
FAD  A 315 (-3.4A)
None
FAD  A 315 ( 4.0A)
None
None
 0.29A 5vw9A-1bx0A:
41.5		 5vw9A-1bx0A:
48.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 1bx0 PROTEIN
(FERREDOXIN:NADP+
OXIDOREDUCTASE)
(Spinacia
oleracea) 		4 / 6 ILE A  97
TYR A  70
ARG A 178
SER A 179
 None
 1.24A 6f6jA-1bx0A:
0.0		 6f6jA-1bx0A:
21.50