SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bxc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 12 ARG A 307
GLY A 304
LEU A  45
VAL A  47
PHE A  12
None
1.15A 1gseA-1bxcA:
undetectable
1gseA-1bxcA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 12 ARG A 307
GLY A 304
LEU A  45
VAL A  47
PHE A  12
None
1.10A 1gseB-1bxcA:
0.0
1gseB-1bxcA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 11 THR A  11
TYR A 309
LEU A 240
VAL A 231
PHE A 227
None
1.37A 1q23L-1bxcA:
0.0
1q23L-1bxcA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
4 / 4 VAL A 271
ALA A 267
LEU A 382
PHE A 268
None
1.26A 1q97B-1bxcA:
0.0
1q97B-1bxcA:
21.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 10 HIS A  53
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.47A 1xidA-1bxcA:
53.5
1xidA-1bxcA:
58.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
9 / 10 TRP A  15
HIS A  53
PHE A  93
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
ASP A 286
None
0.29A 1xidA-1bxcA:
53.5
1xidA-1bxcA:
58.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
6 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.46A 1xihA-1bxcA:
53.3
1xihA-1bxcA:
58.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
11 / 12 TRP A  15
HIS A  53
THR A  89
PHE A  93
VAL A 134
TRP A 136
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 286
None
0.28A 1xihA-1bxcA:
53.3
1xihA-1bxcA:
58.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
9 / 12 TRP A  15
HIS A  53
THR A  89
PHE A  93
VAL A 134
TRP A 136
LYS A 182
HIS A 219
ASP A 254
None
0.73A 1xihA-1bxcA:
53.3
1xihA-1bxcA:
58.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
3 / 3 PHE A 227
ARG A 249
ASN A 263
None
0.73A 1xzxX-1bxcA:
0.0
1xzxX-1bxcA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
4 / 8 ASP A  56
GLU A  55
HIS A  53
SER A  94
None
0.99A 2q0iA-1bxcA:
undetectable
2q0iA-1bxcA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
4 / 7 TYR A 369
PRO A 360
ALA A 363
LEU A 361
None
1.03A 2vcvA-1bxcA:
0.0
2vcvA-1bxcA:
20.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
6 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.40A 2xinA-1bxcA:
53.0
2xinA-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
HIS A 219
ASP A 256
None
1.37A 2xinA-1bxcA:
53.0
2xinA-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 12 THR A  89
GLU A 216
HIS A 219
ASP A 256
ASP A 244
None
1.27A 2xinA-1bxcA:
53.0
2xinA-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 286
None
0.43A 2xinA-1bxcA:
53.0
2xinA-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
6 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.42A 2xinB-1bxcA:
52.8
2xinB-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
HIS A 219
ASP A 256
None
1.36A 2xinB-1bxcA:
52.8
2xinB-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 12 THR A  89
GLU A 216
HIS A 219
ASP A 254
ASP A 244
None
1.42A 2xinB-1bxcA:
52.8
2xinB-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 12 THR A  89
GLU A 216
HIS A 219
ASP A 256
ASP A 244
None
1.24A 2xinB-1bxcA:
52.8
2xinB-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 286
None
0.53A 2xinB-1bxcA:
52.8
2xinB-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
6 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.41A 2xinC-1bxcA:
52.9
2xinC-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
HIS A 219
ASP A 256
None
1.39A 2xinC-1bxcA:
52.9
2xinC-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 12 THR A  89
GLU A 216
HIS A 219
ASP A 256
ASP A 244
None
1.27A 2xinC-1bxcA:
52.9
2xinC-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 286
None
0.49A 2xinC-1bxcA:
52.9
2xinC-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
6 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.42A 2xinD-1bxcA:
52.9
2xinD-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
HIS A 219
ASP A 256
None
1.36A 2xinD-1bxcA:
52.9
2xinD-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 12 THR A  89
GLU A 216
HIS A 219
ASP A 256
ASP A 244
None
1.23A 2xinD-1bxcA:
52.9
2xinD-1bxcA:
54.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 286
None
0.53A 2xinD-1bxcA:
52.9
2xinD-1bxcA:
54.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
4 / 6 ASP A 272
LEU A 274
LEU A 310
HIS A   8
None
1.23A 3bj8C-1bxcA:
0.8
3bj8D-1bxcA:
0.8
3bj8C-1bxcA:
15.79
3bj8D-1bxcA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 9 VAL A 157
LEU A 205
ARG A 158
ILE A 202
GLY A 138
None
1.08A 3cv9A-1bxcA:
0.0
3cv9A-1bxcA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 12 LEU A 371
LEU A 374
GLN A 376
ALA A 378
LEU A 269
None
1.32A 3gwuA-1bxcA:
0.4
3gwuA-1bxcA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
3 / 3 GLU A 216
GLU A 180
TRP A  15
None
1.29A 3hrdA-1bxcA:
0.0
3hrdE-1bxcA:
0.0
3hrdF-1bxcA:
0.0
3hrdA-1bxcA:
22.73
3hrdE-1bxcA:
22.73
3hrdF-1bxcA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 12 LEU A 124
GLY A 129
ALA A 130
ILE A 132
GLY A  49
None
0.76A 3ogqB-1bxcA:
undetectable
3ogqB-1bxcA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
4 / 7 ALA A 234
GLY A 212
ILE A 202
THR A 194
None
0.89A 3spkB-1bxcA:
0.0
3spkB-1bxcA:
11.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 HIS A  53
MET A  87
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.40A 3ximA-1bxcA:
52.9
3ximA-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
6 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 216
ASP A 244
ASP A 256
None
1.17A 3ximA-1bxcA:
52.9
3ximA-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
12 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 286
None
0.43A 3ximA-1bxcA:
52.9
3ximA-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 286
None
1.38A 3ximB-1bxcA:
53.0
3ximB-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 244
ASP A 256
None
1.19A 3ximB-1bxcA:
53.0
3ximB-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 286
None
0.40A 3ximB-1bxcA:
53.0
3ximB-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 MET A  87
THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 286
None
1.34A 3ximC-1bxcA:
52.6
3ximC-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
6 / 12 THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 244
ASP A 256
None
1.19A 3ximC-1bxcA:
52.6
3ximC-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
12 / 12 TRP A  15
MET A  87
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 286
None
0.38A 3ximC-1bxcA:
52.6
3ximC-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
6 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.46A 3ximD-1bxcA:
53.0
3ximD-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 244
ASP A 256
None
1.16A 3ximD-1bxcA:
53.0
3ximD-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 12 THR A  89
GLU A 180
GLU A 216
HIS A 219
ASP A 244
None
1.28A 3ximD-1bxcA:
53.0
3ximD-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 286
None
0.41A 3ximD-1bxcA:
53.0
3ximD-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
6 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.43A 4dvoA-1bxcA:
53.5
4dvoA-1bxcA:
58.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 HIS A  53
THR A  89
VAL A 134
ASN A 214
GLU A 216
ASP A 244
ASP A 256
None
1.25A 4dvoA-1bxcA:
53.5
4dvoA-1bxcA:
58.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
12 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
ASN A 214
GLU A 216
HIS A 219
ASP A 244
ASP A 254
None
0.32A 4dvoA-1bxcA:
53.5
4dvoA-1bxcA:
58.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 12 LEU A 377
LEU A 374
LEU A 371
ALA A 370
ALA A 330
None
1.04A 4fn9A-1bxcA:
undetectable
4fn9A-1bxcA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
4 / 8 THR A  89
GLU A  55
ASP A  56
ASP A  54
None
1.15A 4qb9D-1bxcA:
0.0
4qb9D-1bxcA:
24.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 HIS A  53
MET A  87
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.42A 4xiaA-1bxcA:
52.3
4xiaA-1bxcA:
51.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
11 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 286
None
0.31A 4xiaA-1bxcA:
52.3
4xiaA-1bxcA:
51.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
10 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
HIS A 219
ASP A 244
ASP A 254
None
0.70A 4xiaA-1bxcA:
52.3
4xiaA-1bxcA:
51.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 286
None
1.36A 4xiaB-1bxcA:
52.3
4xiaB-1bxcA:
51.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
12 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 286
None
0.35A 4xiaB-1bxcA:
52.3
4xiaB-1bxcA:
51.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
4 / 7 GLY A 138
GLY A 141
GLU A 143
SER A 197
None
0.89A 4z53A-1bxcA:
undetectable
4z53B-1bxcA:
undetectable
4z53A-1bxcA:
19.84
4z53B-1bxcA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
3 / 3 LEU A 128
LEU A  78
ARG A   9
None
0.33A 5hnzB-1bxcA:
undetectable
5hnzB-1bxcA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
4 / 6 HIS A 242
ASP A 244
HIS A 284
MET A  87
None
1.37A 5m45A-1bxcA:
0.0
5m45A-1bxcA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
4 / 6 HIS A 242
ASP A 244
HIS A 284
MET A  87
None
1.36A 5m45D-1bxcA:
0.0
5m45D-1bxcA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
4 / 6 HIS A 242
ASP A 244
HIS A 284
MET A  87
None
1.36A 5m45G-1bxcA:
0.0
5m45G-1bxcA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
4 / 6 HIS A 242
ASP A 244
HIS A 284
MET A  87
None
1.37A 5m45J-1bxcA:
0.0
5m45J-1bxcA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_A_SORA503_0
(XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 9 HIS A  53
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.42A 5nhaA-1bxcA:
40.1
5nhaA-1bxcA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_A_SORA503_0
(XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
8 / 9 TRP A  15
HIS A  53
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
ASP A 286
None
0.33A 5nhaA-1bxcA:
40.1
5nhaA-1bxcA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_B_SORB503_0
(XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 9 HIS A  53
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.43A 5nhaB-1bxcA:
40.1
5nhaB-1bxcA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_B_SORB503_0
(XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
8 / 9 TRP A  15
HIS A  53
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
ASP A 286
None
0.33A 5nhaB-1bxcA:
40.1
5nhaB-1bxcA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 9 HIS A  53
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.43A 5nhaC-1bxcA:
40.0
5nhaC-1bxcA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
8 / 9 TRP A  15
HIS A  53
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
ASP A 286
None
0.33A 5nhaC-1bxcA:
40.0
5nhaC-1bxcA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 9 HIS A  53
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.42A 5nhaD-1bxcA:
40.1
5nhaD-1bxcA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
8 / 9 TRP A  15
HIS A  53
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 244
ASP A 286
None
0.33A 5nhaD-1bxcA:
40.1
5nhaD-1bxcA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
3 / 3 LEU A 235
ALA A 234
LEU A 273
None
0.45A 5uunB-1bxcA:
0.0
5uunB-1bxcA:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
6 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.47A 5ximA-1bxcA:
53.1
5ximA-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 244
ASP A 256
None
1.18A 5ximA-1bxcA:
53.1
5ximA-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 286
None
0.34A 5ximA-1bxcA:
53.1
5ximA-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 HIS A  53
MET A  87
THR A  89
TRP A 136
GLU A 216
HIS A 219
ASP A 286
None
1.39A 5ximB-1bxcA:
53.0
5ximB-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 216
ASP A 256
None
1.32A 5ximB-1bxcA:
53.0
5ximB-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
12 / 12 TRP A  15
HIS A  53
MET A  87
THR A  89
VAL A 134
TRP A 136
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 286
None
0.37A 5ximB-1bxcA:
53.0
5ximB-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 HIS A  53
THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 286
None
1.38A 5ximC-1bxcA:
53.0
5ximC-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
6 / 12 HIS A  53
THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 256
None
1.25A 5ximC-1bxcA:
53.0
5ximC-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
12 / 12 TRP A  15
HIS A  53
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 286
None
0.38A 5ximC-1bxcA:
53.0
5ximC-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
7 / 12 MET A  87
THR A  89
TRP A 136
GLU A 180
GLU A 216
HIS A 219
ASP A 286
None
1.36A 5ximD-1bxcA:
53.1
5ximD-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 12 THR A  89
VAL A 134
GLU A 180
GLU A 216
ASP A 256
None
1.20A 5ximD-1bxcA:
53.1
5ximD-1bxcA:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
12 / 12 TRP A  15
MET A  87
THR A  89
VAL A 134
TRP A 136
GLU A 180
LYS A 182
GLU A 216
HIS A 219
ASP A 244
ASP A 254
ASP A 286
None
0.39A 5ximD-1bxcA:
53.1
5ximD-1bxcA:
54.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
5 / 12 ARG A 187
GLY A 101
ARG A 111
THR A 147
GLY A 148
None
1.13A 6brdC-1bxcA:
undetectable
6brdC-1bxcA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
4 / 5 GLN A 255
THR A  16
HIS A 284
GLY A 247
None
1.21A 6gbnC-1bxcA:
2.2
6gbnC-1bxcA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
4 / 5 ASN A  51
GLY A 212
HIS A 242
ASP A 244
None
1.27A 6gh9A-1bxcA:
undetectable
6gh9A-1bxcA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)
1bxc XYLOSE ISOMERASE
(Thermus
caldophilus)
4 / 8 ASP A  56
HIS A 288
ASP A 286
GLU A 180
None
1.19A 6mn4C-1bxcA:
0.0
6mn4C-1bxcA:
23.25