SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bxn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN)
(Cupriavidus
necator) 		5 / 9 ILE I  68
LEU I  58
VAL I  33
GLY I  34
LEU I  23
 None
 1.15A 1e7bA-1bxnI:
undetectable		 1e7bA-1bxnI:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		4 / 7 LEU A 402
MET A 269
TYR A 242
LEU A 200
 None
 1.03A 1kt3A-1bxnA:
0.0		 1kt3A-1bxnA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		5 / 12 HIS A 294
ILE A 384
LEU A 402
GLY A 174
ALA A 380
 None
 0.99A 2oc8A-1bxnA:
0.0		 2oc8A-1bxnA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		4 / 7 ILE A 124
ARG A  44
PHE A  43
ILE A  45
 None
 1.09A 2q6hA-1bxnA:
0.0		 2q6hA-1bxnA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN)
(Cupriavidus
necator;
Cupriavidus
necator) 		3 / 3 LEU I  11
PRO I  12
ARG A 437
 None
 0.49A 2qd4B-1bxnI:
undetectable		 2qd4B-1bxnI:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN)
(Cupriavidus
necator;
Cupriavidus
necator) 		3 / 3 LEU I  11
PRO I  12
ARG A 437
 None
 0.51A 2qd5A-1bxnI:
undetectable		 2qd5A-1bxnI:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN)
(Cupriavidus
necator) 		5 / 12 LEU I  27
LEU I  23
LEU I  65
ARG I  72
MET I  96
 None
 1.33A 2w8yB-1bxnI:
undetectable		 2w8yB-1bxnI:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		4 / 6 GLN A 416
ALA A 227
ALA A 231
THR A 235
 None
 0.97A 2xfhA-1bxnA:
undetectable		 2xfhA-1bxnA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_A_TESA339_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		5 / 10 TYR A 242
ILE A 292
THR A 177
VAL A 192
VAL A 224
 None
 1.50A 3burA-1bxnA:
11.5		 3burA-1bxnA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_B_TESB340_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		5 / 10 TYR A 242
ILE A 292
THR A 177
VAL A 192
VAL A 224
 None
 1.46A 3burB-1bxnA:
11.4		 3burB-1bxnA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		5 / 9 PHE A 313
VAL A 344
GLY A 339
ARG A 305
GLY A 331
 None
None
None
None
PO4  A 501 ( 4.9A)
 1.32A 3csjB-1bxnA:
undetectable		 3csjB-1bxnA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN)
(Cupriavidus
necator) 		5 / 12 LEU I  27
LEU I  23
LEU I  65
ARG I  72
MET I  96
 None
 1.32A 3d90A-1bxnI:
undetectable		 3d90A-1bxnI:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		4 / 4 ARG A 433
ASP A 399
ASP A 398
PRO A 171
 None
 1.49A 3fgrB-1bxnA:
0.0		 3fgrB-1bxnA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN)
(Cupriavidus
necator) 		5 / 12 TYR I 123
ILE A 409
GLY A 189
GLY A 195
LEU A 196
 None
 0.96A 3hs6B-1bxnI:
undetectable		 3hs6B-1bxnI:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		5 / 12 PHE A 111
LEU A  40
ILE A 124
PHE A  43
GLY A 310
 None
 0.92A 4dm8B-1bxnA:
0.0		 4dm8B-1bxnA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN)
(Cupriavidus
necator) 		5 / 12 TYR I 123
ILE A 409
GLY A 189
GLY A 195
LEU A 196
 None
 0.97A 4e1gA-1bxnI:
0.8		 4e1gA-1bxnI:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN)
(Cupriavidus
necator) 		5 / 12 TYR I 123
ILE A 409
GLY A 189
GLY A 195
LEU A 196
 None
 0.95A 4e1gB-1bxnI:
2.3		 4e1gB-1bxnI:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN)
(Cupriavidus
necator) 		4 / 8 GLY I  52
GLY I  34
GLU I  36
TYR I  37
 None
 0.90A 4fgzA-1bxnI:
undetectable		 4fgzA-1bxnI:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN)
(Cupriavidus
necator;
Cupriavidus
necator) 		4 / 7 GLU A 435
TYR I  25
ARG A 433
GLY A 169
 None
 1.08A 4fgzA-1bxnA:
undetectable		 4fgzA-1bxnA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		5 / 12 GLY A 324
PRO A 154
GLY A 153
PHE A 151
LEU A 295
 None
 1.22A 4n48A-1bxnA:
undetectable		 4n48A-1bxnA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN)
(Cupriavidus
necator) 		5 / 12 VAL A 430
CYH A 454
LEU A 457
ALA A 450
THR I   7
 None
 1.16A 4x1kA-1bxnA:
undetectable
4x1kB-1bxnA:
undetectable		 4x1kA-1bxnA:
21.85
4x1kB-1bxnA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUQ_A_ACTA1278_0
(NAD(P)H
DEHYDROGENASE
[QUINONE] 1)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN)
(Cupriavidus
necator) 		4 / 5 SER I 127
GLN I   5
ILE I   3
TYR I  79
 None
 1.41A 5fuqA-1bxnI:
0.0
5fuqB-1bxnI:
0.0		 5fuqA-1bxnI:
18.98
5fuqB-1bxnI:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		3 / 3 ILE A 267
MET A 253
ASP A 205
 None
 0.85A 5h2uA-1bxnA:
undetectable		 5h2uA-1bxnA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		4 / 5 GLY A 248
THR A 249
GLY A 310
LEU A 272
 None
 0.56A 5jlcA-1bxnA:
0.0		 5jlcA-1bxnA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		5 / 12 VAL A 104
ASN A 126
GLY A  62
ALA A  61
LEU A 110
 None
 1.28A 5x23A-1bxnA:
0.0		 5x23A-1bxnA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		3 / 3 ASP A 201
ARG A 423
ASP A 166
 None
 0.77A 5zvgA-1bxnA:
undetectable		 5zvgA-1bxnA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		3 / 3 ASP A 201
ARG A 423
ASP A 166
 None
 0.82A 5zvgB-1bxnA:
undetectable		 5zvgB-1bxnA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)
(Cupriavidus
necator) 		3 / 3 SER A  65
SER A  64
ALA A  87
 None
 0.72A 6dwnC-1bxnA:
0.0		 6dwnC-1bxnA:
10.37