SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1bxu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE1_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1bxu	PLASTOCYANIN (Synechococcus elongatus)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 200 ( 3.0A) CU A 200 ( 2.1A) CU A 200 ( 3.0A) CU A 200 ( 2.9A)	0.41A	1oe1A-1bxuA: 4.3	1oe1A-1bxuA: 15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE2_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1bxu	PLASTOCYANIN (Synechococcus elongatus)	5 / 5	HIS A 37 CYH A 84 PRO A 86 HIS A 87 MET A 92	CU A 200 ( 3.0A) CU A 200 ( 2.1A) CU A 200 ( 4.9A) CU A 200 ( 3.0A) CU A 200 ( 2.9A)	0.78A	1oe2A-1bxuA: 7.2	1oe2A-1bxuA: 15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE3_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1bxu	PLASTOCYANIN (Synechococcus elongatus)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 200 ( 3.0A) CU A 200 ( 2.1A) CU A 200 ( 3.0A) CU A 200 ( 2.9A)	0.45A	1oe3A-1bxuA: 4.4	1oe3A-1bxuA: 15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQD_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1bxu	PLASTOCYANIN (Synechococcus elongatus)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 200 ( 3.0A) CU A 200 ( 2.1A) CU A 200 ( 3.0A) CU A 200 ( 2.9A)	0.39A	2fqdA-1bxuA: 4.2	2fqdA-1bxuA: 12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQE_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1bxu	PLASTOCYANIN (Synechococcus elongatus)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 200 ( 3.0A) CU A 200 ( 2.1A) CU A 200 ( 3.0A) CU A 200 ( 2.9A)	0.34A	2fqeA-1bxuA: 4.2	2fqeA-1bxuA: 12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQF_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1bxu	PLASTOCYANIN (Synechococcus elongatus)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 200 ( 3.0A) CU A 200 ( 2.1A) CU A 200 ( 3.0A) CU A 200 ( 2.9A)	0.33A	2fqfA-1bxuA: 4.2	2fqfA-1bxuA: 12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQG_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1bxu	PLASTOCYANIN (Synechococcus elongatus)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 200 ( 3.0A) CU A 200 ( 2.1A) CU A 200 ( 3.0A) CU A 200 ( 2.9A)	0.33A	2fqgA-1bxuA: 4.2	2fqgA-1bxuA: 12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_A_CUA1337_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1bxu	PLASTOCYANIN (Synechococcus elongatus)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 200 ( 3.0A) CU A 200 ( 2.1A) CU A 200 ( 3.0A) CU A 200 ( 2.9A)	0.42A	2xxgA-1bxuA: 7.2	2xxgA-1bxuA: 15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_C_CUC1338_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1bxu	PLASTOCYANIN (Synechococcus elongatus)	5 / 5	HIS A 37 CYH A 84 PRO A 86 HIS A 87 MET A 92	CU A 200 ( 3.0A) CU A 200 ( 2.1A) CU A 200 ( 4.9A) CU A 200 ( 3.0A) CU A 200 ( 2.9A)	0.83A	2xxgC-1bxuA: 7.1	2xxgC-1bxuA: 15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EF3_A_CUA1001_0 (BLUE COPPER OXIDASE CUEO)	1bxu	PLASTOCYANIN (Synechococcus elongatus)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 200 ( 3.0A) CU A 200 ( 2.1A) CU A 200 ( 3.0A) CU A 200 ( 2.9A)	0.30A	4ef3A-1bxuA: 4.1	4ef3A-1bxuA: 9.59

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1OE1_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1bxu","PLASTOCYANIN","Synechococcus elongatus",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 200 ( 3.0A); CU A 200 ( 2.1A); CU A 200 ( 3.0A); CU A 200 ( 2.9A)","0.41A","1oe1A-1bxuA:4.3","1oe1A-1bxuA:15.55"],["1OE2_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1bxu","PLASTOCYANIN","Synechococcus elongatus",5,"HIS A  37;CYH A  84;PRO A  86;HIS A  87;MET A  92"," CU A 200 ( 3.0A); CU A 200 ( 2.1A); CU A 200 ( 4.9A); CU A 200 ( 3.0A); CU A 200 ( 2.9A)","0.78A","1oe2A-1bxuA:7.2","1oe2A-1bxuA:15.55"],["1OE3_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1bxu","PLASTOCYANIN","Synechococcus elongatus",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 200 ( 3.0A); CU A 200 ( 2.1A); CU A 200 ( 3.0A); CU A 200 ( 2.9A)","0.45A","1oe3A-1bxuA:4.4","1oe3A-1bxuA:15.55"],["2FQD_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1bxu","PLASTOCYANIN","Synechococcus elongatus",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 200 ( 3.0A); CU A 200 ( 2.1A); CU A 200 ( 3.0A); CU A 200 ( 2.9A)","0.39A","2fqdA-1bxuA:4.2","2fqdA-1bxuA:12.69"],["2FQE_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1bxu","PLASTOCYANIN","Synechococcus elongatus",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 200 ( 3.0A); CU A 200 ( 2.1A); CU A 200 ( 3.0A); CU A 200 ( 2.9A)","0.34A","2fqeA-1bxuA:4.2","2fqeA-1bxuA:12.69"],["2FQF_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1bxu","PLASTOCYANIN","Synechococcus elongatus",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 200 ( 3.0A); CU A 200 ( 2.1A); CU A 200 ( 3.0A); CU A 200 ( 2.9A)","0.33A","2fqfA-1bxuA:4.2","2fqfA-1bxuA:12.69"],["2FQG_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1bxu","PLASTOCYANIN","Synechococcus elongatus",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 200 ( 3.0A); CU A 200 ( 2.1A); CU A 200 ( 3.0A); CU A 200 ( 2.9A)","0.33A","2fqgA-1bxuA:4.2","2fqgA-1bxuA:12.69"],["2XXG_A_CUA1337_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1bxu","PLASTOCYANIN","Synechococcus elongatus",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 200 ( 3.0A); CU A 200 ( 2.1A); CU A 200 ( 3.0A); CU A 200 ( 2.9A)","0.42A","2xxgA-1bxuA:7.2","2xxgA-1bxuA:15.85"],["2XXG_C_CUC1338_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1bxu","PLASTOCYANIN","Synechococcus elongatus",5,"HIS A  37;CYH A  84;PRO A  86;HIS A  87;MET A  92"," CU A 200 ( 3.0A); CU A 200 ( 2.1A); CU A 200 ( 4.9A); CU A 200 ( 3.0A); CU A 200 ( 2.9A)","0.83A","2xxgC-1bxuA:7.1","2xxgC-1bxuA:15.85"],["4EF3_A_CUA1001_0","BLUE COPPER OXIDASE CUEO","1bxu","PLASTOCYANIN","Synechococcus elongatus",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 200 ( 3.0A); CU A 200 ( 2.1A); CU A 200 ( 3.0A); CU A 200 ( 2.9A)","0.30A","4ef3A-1bxuA:4.1","4ef3A-1bxuA:9.59"]]