SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1byr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1byr PROTEIN
(ENDONUCLEASE)
(Salmonella
enterica) 		3 / 3 ARG A 152
ASP A  55
ASN A 102
 None
 0.96A 1nbhA-1byrA:
2.1		 1nbhA-1byrA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1byr PROTEIN
(ENDONUCLEASE)
(Salmonella
enterica) 		3 / 3 ARG A 152
ASP A  55
ASN A 102
 None
 0.92A 1nbhD-1byrA:
2.2		 1nbhD-1byrA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 1byr PROTEIN
(ENDONUCLEASE)
(Salmonella
enterica) 		3 / 3 ALA A  34
VAL A  59
TRP A 141
 None
 0.99A 2izqA-1byrA:
undetectable
2izqB-1byrA:
undetectable		 2izqA-1byrA:
7.75
2izqB-1byrA:
7.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 1byr PROTEIN
(ENDONUCLEASE)
(Salmonella
enterica) 		3 / 3 HIS A 140
ILE A  99
LEU A 133
 None
 0.53A 2kceA-1byrA:
0.0		 2kceA-1byrA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_A_ACTA511_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1byr PROTEIN
(ENDONUCLEASE)
(Salmonella
enterica) 		4 / 4 ASN A  89
PHE A  90
SER A  88
GLN A  93
 None
 1.23A 3v5vA-1byrA:
0.0		 3v5vA-1byrA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1byr PROTEIN
(ENDONUCLEASE)
(Salmonella
enterica) 		4 / 8 PHE A 110
VAL A  19
ILE A  23
GLU A 122
 None
 0.97A 4a97D-1byrA:
undetectable		 4a97D-1byrA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1byr PROTEIN
(ENDONUCLEASE)
(Salmonella
enterica) 		4 / 7 PHE A 110
VAL A  19
ILE A  23
GLU A 122
 None
 1.08A 4a97H-1byrA:
0.0		 4a97H-1byrA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 1byr PROTEIN
(ENDONUCLEASE)
(Salmonella
enterica) 		4 / 6 PHE A 110
ALA A 116
ALA A  39
PRO A  40
 None
 1.13A 4dtzB-1byrA:
0.0		 4dtzB-1byrA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1byr PROTEIN
(ENDONUCLEASE)
(Salmonella
enterica) 		3 / 3 SER A  21
ALA A  22
THR A 104
 None
 0.72A 5n0xB-1byrA:
undetectable		 5n0xB-1byrA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 1byr PROTEIN
(ENDONUCLEASE)
(Salmonella
enterica) 		3 / 3 VAL A 125
LYS A  96
MET A  33
 None
 0.90A 5nknA-1byrA:
0.0		 5nknA-1byrA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1byr PROTEIN
(ENDONUCLEASE)
(Salmonella
enterica) 		5 / 8 ILE A  77
LEU A  46
ILE A  58
ILE A  60
ASN A  65
 None
 1.27A 5numA-1byrA:
0.0		 5numA-1byrA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1byr PROTEIN
(ENDONUCLEASE)
(Salmonella
enterica) 		6 / 9 ALA A  39
ILE A  77
LEU A  46
ILE A  58
ILE A  60
ASN A  65
 None
 1.37A 5nunA-1byrA:
0.0		 5nunA-1byrA:
22.06