SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1byw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 1byw PROTEIN (HUMAN ERG
POTASSIUM CHANNEL)
(Homo
sapiens) 		4 / 7 ILE A  82
PHE A 129
PHE A  48
PHE A  68
 None
 1.20A 1e71M-1bywA:
undetectable		 1e71M-1bywA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 1byw PROTEIN (HUMAN ERG
POTASSIUM CHANNEL)
(Homo
sapiens) 		4 / 7 ILE A  96
PHE A 129
PHE A  48
PHE A  68
 None
 1.01A 1e71M-1bywA:
undetectable		 1e71M-1bywA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 1byw PROTEIN (HUMAN ERG
POTASSIUM CHANNEL)
(Homo
sapiens) 		4 / 7 ILE A  82
PHE A 129
PHE A  48
PHE A  68
 None
 1.18A 1e72M-1bywA:
undetectable		 1e72M-1bywA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 1byw PROTEIN (HUMAN ERG
POTASSIUM CHANNEL)
(Homo
sapiens) 		4 / 7 ILE A  96
PHE A 129
PHE A  48
PHE A  68
 None
 1.01A 1e72M-1bywA:
undetectable		 1e72M-1bywA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P9G_A_ACTA42_0
(EAFP 2)		 1byw PROTEIN (HUMAN ERG
POTASSIUM CHANNEL)
(Homo
sapiens) 		3 / 3 CYH A  44
ARG A  56
CYH A  49
 None
 1.45A 1p9gA-1bywA:
0.0		 1p9gA-1bywA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1byw PROTEIN (HUMAN ERG
POTASSIUM CHANNEL)
(Homo
sapiens) 		3 / 3 ASN A  45
ILE A  42
MET A 124
 None
 0.75A 2h42C-1bywA:
undetectable		 2h42C-1bywA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 1byw PROTEIN (HUMAN ERG
POTASSIUM CHANNEL)
(Homo
sapiens) 		3 / 3 PHE A  48
CYH A  52
PHE A 106
 None
 1.07A 3cr5X-1bywA:
undetectable		 3cr5X-1bywA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 1byw PROTEIN (HUMAN ERG
POTASSIUM CHANNEL)
(Homo
sapiens) 		5 / 9 LEU A  69
ILE A  82
LEU A  86
ILE A  96
PHE A 125
 None
 0.63A 4kukA-1bywA:
17.6		 4kukA-1bywA:
29.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1byw PROTEIN (HUMAN ERG
POTASSIUM CHANNEL)
(Homo
sapiens) 		3 / 3 PHE A 129
ILE A  30
ASP A  46
 None
 0.75A 5cswA-1bywA:
0.0		 5cswA-1bywA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 1byw PROTEIN (HUMAN ERG
POTASSIUM CHANNEL)
(Homo
sapiens) 		5 / 12 THR A  74
ILE A  96
ALA A  32
ARG A  62
LEU A  86
 None
 1.18A 6ie8A-1bywA:
undetectable		 6ie8A-1bywA:
21.13