SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c0w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HK3_A_T44A3002_1 (SERUM ALBUMIN)	1c0w	DIPHTHERIA TOXIN REPRESSOR (Corynebacterium diphtheriae)	4 / 8	GLN A 173 ASN A 169 ARG A 13 TYR A 16	CO A 601 (-2.6A) None CO A 701 ( 4.9A) None	1.10A	1hk3A-1c0wA: 0.4	1hk3A-1c0wA: 16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IJD_B_C2FB314_1 (UNCHARACTERIZED PROTEIN)	1c0w	DIPHTHERIA TOXIN REPRESSOR (Corynebacterium diphtheriae)	3 / 3	THR A 180 LYS A 2 GLU A 175	None	1.02A	3ijdB-1c0wA: undetectable	3ijdB-1c0wA: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JW1_B_CELB602_2 (PROSTAGLANDIN G/H SYNTHASE 2)	1c0w	DIPHTHERIA TOXIN REPRESSOR (Corynebacterium diphtheriae)	4 / 6	VAL A 56 SER A 61 ARG A 29 ILE A 15	None	1.00A	5jw1B-1c0wA: 0.0	5jw1B-1c0wA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZW2_A_ACTA511_0 (L-PROLYL-[PEPTIDYL-C ARRIER PROTEIN] DEHYDROGENASE)	1c0w	DIPHTHERIA TOXIN REPRESSOR (Corynebacterium diphtheriae)	3 / 3	ARG A 80 ILE A 132 SER A 126	None	0.76A	5zw2A-1c0wA: 0.0	5zw2A-1c0wA: 19.49

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HK3_A_T44A3002_1","SERUM ALBUMIN","1c0w","DIPHTHERIA TOXIN REPRESSOR","Corynebacterium diphtheriae",4,"GLN A 173;ASN A 169;ARG A  13;TYR A  16"," CO A 601 (-2.6A);None; CO A 701 ( 4.9A);None","1.10A","1hk3A-1c0wA:0.4","1hk3A-1c0wA:16.98"],["3IJD_B_C2FB314_1","UNCHARACTERIZED PROTEIN","1c0w","DIPHTHERIA TOXIN REPRESSOR","Corynebacterium diphtheriae",3,"THR A 180;LYS A   2;GLU A 175","None","1.02A","3ijdB-1c0wA:undetectable","3ijdB-1c0wA:21.32"],["5JW1_B_CELB602_2","PROSTAGLANDIN G\/H SYNTHASE 2","1c0w","DIPHTHERIA TOXIN REPRESSOR","Corynebacterium diphtheriae",4,"VAL A  56;SER A  61;ARG A  29;ILE A  15","None","1.00A","5jw1B-1c0wA:0.0","5jw1B-1c0wA:18.75"],["5ZW2_A_ACTA511_0","L-PROLYL-[PEPTIDYL-CARRIER PROTEIN] DEHYDROGENASE","1c0w","DIPHTHERIA TOXIN REPRESSOR","Corynebacterium diphtheriae",3,"ARG A  80;ILE A 132;SER A 126","None","0.76A","5zw2A-1c0wA:0.0","5zw2A-1c0wA:19.49"]]