SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c12'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 1c12 PROTEIN (ANTIBODY
FRAGMENT FAB)
(Mus
musculus) 		5 / 12 ARG B 366
SER B 362
LEU B 380
LEU B 318
ASP B 386
 None
 1.40A 1e7wA-1c12B:
undetectable		 1e7wA-1c12B:
23.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1c12 PROTEIN (ANTIBODY
FRAGMENT FAB)
(Mus
musculus) 		4 / 8 ALA B  33
ASN B  35
TRP B  47
TYR B  50
 None
 0.46A 1rukH-1c12B:
22.9
1rukL-1c12B:
15.1		 1rukH-1c12B:
81.45
1rukL-1c12B:
26.89