SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c1k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 1c1k BPT4 GENE 59
HELICASE ASSEMBLY
PROTEIN
(Escherichia
virus
T4) 		5 / 12 LEU A  71
TRP A  41
MET A   6
LEU A 106
VAL A  36
 None
 1.30A 2w8yA-1c1kA:
undetectable		 2w8yA-1c1kA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_A_AC2A301_1
(DEOXYCYTIDINE KINASE)		 1c1k BPT4 GENE 59
HELICASE ASSEMBLY
PROTEIN
(Escherichia
virus
T4) 		5 / 9 ILE A  74
ARG A  53
ASP A  55
PHE A  58
LEU A  96
 None
 1.10A 3mjrA-1c1kA:
undetectable		 3mjrA-1c1kA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1c1k BPT4 GENE 59
HELICASE ASSEMBLY
PROTEIN
(Escherichia
virus
T4) 		4 / 5 TYR A  13
LEU A  71
GLU A  70
TYR A  66
 None
 1.37A 4olaA-1c1kA:
undetectable		 4olaA-1c1kA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 1c1k BPT4 GENE 59
HELICASE ASSEMBLY
PROTEIN
(Escherichia
virus
T4) 		4 / 8 ALA A  72
GLY A  10
LEU A  68
LEU A  22
 None
 0.80A 4po0A-1c1kA:
0.3		 4po0A-1c1kA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 1c1k BPT4 GENE 59
HELICASE ASSEMBLY
PROTEIN
(Escherichia
virus
T4) 		5 / 11 LEU A 151
PHE A 113
LEU A 168
ASP A 116
PHE A 167
 None
 1.31A 4wnuC-1c1kA:
0.0		 4wnuC-1c1kA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1c1k BPT4 GENE 59
HELICASE ASSEMBLY
PROTEIN
(Escherichia
virus
T4) 		4 / 6 TYR A  13
LEU A  71
GLU A  70
TYR A  66
 None
 1.31A 4z4cA-1c1kA:
undetectable		 4z4cA-1c1kA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1c1k BPT4 GENE 59
HELICASE ASSEMBLY
PROTEIN
(Escherichia
virus
T4) 		4 / 5 TYR A  13
LEU A  71
GLU A  70
TYR A  66
 None
 1.31A 4z4dA-1c1kA:
undetectable		 4z4dA-1c1kA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1c1k BPT4 GENE 59
HELICASE ASSEMBLY
PROTEIN
(Escherichia
virus
T4) 		4 / 5 TYR A  13
LEU A  71
GLU A  70
TYR A  66
 None
 1.36A 4z4hA-1c1kA:
undetectable		 4z4hA-1c1kA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1c1k BPT4 GENE 59
HELICASE ASSEMBLY
PROTEIN
(Escherichia
virus
T4) 		4 / 5 TYR A  13
LEU A  71
GLU A  70
TYR A  66
 None
 1.39A 5js1A-1c1kA:
undetectable		 5js1A-1c1kA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 1c1k BPT4 GENE 59
HELICASE ASSEMBLY
PROTEIN
(Escherichia
virus
T4) 		5 / 10 ILE A  90
LEU A  71
ASP A  55
PHE A  58
GLU A  64
 None
 1.24A 5tixB-1c1kA:
undetectable		 5tixB-1c1kA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 1c1k BPT4 GENE 59
HELICASE ASSEMBLY
PROTEIN
(Escherichia
virus
T4) 		5 / 10 ILE A  90
VAL A  19
ASP A  55
PHE A  58
GLU A  64
 None
 1.45A 5tixB-1c1kA:
undetectable		 5tixB-1c1kA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 1c1k BPT4 GENE 59
HELICASE ASSEMBLY
PROTEIN
(Escherichia
virus
T4) 		4 / 7 LEU A  24
ILE A  90
TYR A  50
PHE A  59
 None
 0.96A 5zsfA-1c1kA:
undetectable
5zsfB-1c1kA:
undetectable		 5zsfA-1c1kA:
13.62
5zsfB-1c1kA:
13.62