SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c20'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 1c20 DEAD RINGER PROTEIN
(Drosophila
melanogaster) 		5 / 12 LEU A  59
LEU A  56
LEU A  16
GLN A  15
MET A  49
 None
 1.48A 1sqnA-1c20A:
undetectable		 1sqnA-1c20A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1c20 DEAD RINGER PROTEIN
(Drosophila
melanogaster) 		4 / 6 TYR A  60
GLY A  68
TYR A 102
ASP A  71
 None
 1.28A 2g72A-1c20A:
undetectable		 2g72A-1c20A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 1c20 DEAD RINGER PROTEIN
(Drosophila
melanogaster) 		4 / 7 TYR A 105
LEU A  46
GLN A   9
PHE A   6
 None
 1.16A 3jwqC-1c20A:
undetectable		 3jwqC-1c20A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1c20 DEAD RINGER PROTEIN
(Drosophila
melanogaster) 		4 / 7 LEU A  87
THR A  97
LEU A  98
THR A  92
 None
 0.77A 4z91F-1c20A:
undetectable
4z91G-1c20A:
undetectable
4z91H-1c20A:
undetectable
4z91I-1c20A:
undetectable
4z91J-1c20A:
undetectable		 4z91F-1c20A:
19.46
4z91G-1c20A:
19.46
4z91H-1c20A:
19.46
4z91I-1c20A:
19.46
4z91J-1c20A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1c20 DEAD RINGER PROTEIN
(Drosophila
melanogaster) 		5 / 12 GLY A  68
GLY A  67
GLU A 110
ILE A  64
ILE A  81
 None
 1.23A 4zvmA-1c20A:
undetectable
4zvmB-1c20A:
undetectable		 4zvmA-1c20A:
20.08
4zvmB-1c20A:
20.08