SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c2o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 9 TRP A  86
GLY A 120
TRP A 439
HIS A 447
GLY A 448
 None
 0.94A 1acjA-1c2oA:
58.9		 1acjA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 9 TRP A  86
GLY A 121
GLU A 202
TYR A 341
TRP A 439
HIS A 447
GLY A 448
 None
 0.49A 1acjA-1c2oA:
58.9		 1acjA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ACL_A_DMEA999_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		9 / 10 TYR A  72
TRP A  86
TYR A 124
GLU A 202
SER A 203
TRP A 286
TYR A 341
HIS A 447
GLY A 448
 None
 0.61A 1aclA-1c2oA:
58.9		 1aclA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 8 GLY A 121
GLU A 202
SER A 203
PHE A 295
HIS A 447
 None
 1.21A 1ax9A-1c2oA:
59.7		 1ax9A-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 8 GLY A 122
TYR A 124
SER A 203
PHE A 338
HIS A 447
 None
 1.34A 1ax9A-1c2oA:
59.7		 1ax9A-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 TRP A  86
GLY A 120
GLU A 202
HIS A 447
 None
 0.93A 1ax9A-1c2oA:
59.7		 1ax9A-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 8 TRP A  86
GLY A 121
TYR A 124
GLU A 202
SER A 203
PHE A 338
HIS A 447
 None
 0.68A 1ax9A-1c2oA:
59.7		 1ax9A-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		11 / 12 ASP A  74
TRP A  86
GLY A 120
GLY A 121
GLY A 122
TYR A 124
SER A 203
TRP A 236
PHE A 297
PHE A 338
HIS A 447
 None
 0.45A 1dx6A-1c2oA:
59.7		 1dx6A-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 12 GLY A 120
GLY A 121
GLY A 122
SER A 203
PHE A 297
PHE A 295
HIS A 447
 None
 1.16A 1dx6A-1c2oA:
59.7		 1dx6A-1c2oA:
58.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		3 / 3 GLU A 469
TYR A 465
PHE A 453
 None
 0.86A 1eqbB-1c2oA:
undetectable		 1eqbB-1c2oA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		3 / 3 GLU A 469
TYR A 465
PHE A 453
 None
 0.87A 1eqbA-1c2oA:
undetectable		 1eqbA-1c2oA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		3 / 3 GLU A 469
TYR A 465
PHE A 453
 None
 0.87A 1eqbD-1c2oA:
undetectable		 1eqbD-1c2oA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		3 / 3 GLU A 469
TYR A 465
PHE A 453
 None
 0.88A 1eqbC-1c2oA:
undetectable		 1eqbC-1c2oA:
22.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EVE_A_E20A2001_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 10 GLY A 121
GLU A 202
TRP A 286
LEU A 289
PHE A 295
HIS A 447
 None
 1.21A 1eveA-1c2oA:
59.4		 1eveA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EVE_A_E20A2001_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 10 GLY A 122
TYR A 124
PHE A 338
TYR A 341
HIS A 447
 None
 1.28A 1eveA-1c2oA:
59.4		 1eveA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EVE_A_E20A2001_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		9 / 10 TRP A  86
GLY A 121
TYR A 124
GLU A 202
TRP A 286
LEU A 289
PHE A 338
TYR A 341
HIS A 447
 None
 0.56A 1eveA-1c2oA:
59.4		 1eveA-1c2oA:
58.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 11 PHE A 200
ALA A 225
VAL A 411
LEU A 414
ALA A 415
ALA A 419
 None
 1.14A 1jinA-1c2oA:
0.0		 1jinA-1c2oA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 12 GLY A 201
ALA A 225
SER A 208
HIS A 212
LEU A 214
 None
 1.23A 1kiaD-1c2oA:
1.8		 1kiaD-1c2oA:
18.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		10 / 12 TYR A  72
ASP A  74
GLY A 122
TYR A 124
GLU A 202
SER A 203
TRP A 286
TYR A 337
TYR A 341
HIS A 447
 None
 0.94A 1maaA-1c2oA:
66.8		 1maaA-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		12 / 12 TYR A  72
ASP A  74
TRP A  86
GLY A 121
TYR A 124
GLU A 202
SER A 203
TRP A 286
PHE A 297
TYR A 337
TYR A 341
HIS A 447
 None
 0.13A 1maaA-1c2oA:
66.8		 1maaA-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 6 TRP A  86
TYR A 124
GLU A 202
ILE A 294
TYR A 341
 None
 0.32A 1maaB-1c2oA:
64.4
1maaD-1c2oA:
66.6		 1maaB-1c2oA:
99.81
1maaD-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 12 GLY A 121
TYR A 124
TYR A 133
SER A 203
TRP A 286
PHE A 295
HIS A 447
 None
 1.18A 1maaC-1c2oA:
64.0		 1maaC-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		9 / 12 TYR A  72
GLY A 122
TYR A 124
SER A 203
TRP A 286
TYR A 337
PHE A 338
TYR A 341
HIS A 447
 None
 1.09A 1maaC-1c2oA:
64.0		 1maaC-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		12 / 12 TYR A  72
TRP A  86
GLY A 121
TYR A 124
TYR A 133
SER A 203
TRP A 286
PHE A 297
TYR A 337
PHE A 338
TYR A 341
HIS A 447
 None
 0.36A 1maaC-1c2oA:
64.0		 1maaC-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 8 GLY A 122
TYR A 124
GLU A 202
SER A 203
TRP A 286
TYR A 341
HIS A 447
 None
 1.09A 1maaD-1c2oA:
66.6		 1maaD-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 TRP A  86
GLY A 120
SER A 203
HIS A 447
 None
 1.04A 1maaD-1c2oA:
66.6		 1maaD-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		8 / 8 TRP A  86
GLY A 121
TYR A 124
GLU A 202
SER A 203
TRP A 286
TYR A 341
HIS A 447
 None
 0.12A 1maaD-1c2oA:
66.6		 1maaD-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 12 LEU A 308
GLY A 210
LEU A 227
ILE A 316
LEU A 315
 None
 0.91A 1mx1D-1c2oA:
45.9		 1mx1D-1c2oA:
36.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		8 / 12 ASP A  74
GLY A 121
TYR A 124
GLU A 202
SER A 203
PHE A 295
PHE A 338
HIS A 447
 None
 1.05A 1qtiA-1c2oA:
59.7		 1qtiA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		12 / 12 ASP A  74
TRP A  86
GLY A 120
GLY A 121
GLY A 122
TYR A 124
GLU A 202
SER A 203
PHE A 295
PHE A 297
PHE A 338
HIS A 447
 None
 0.46A 1qtiA-1c2oA:
59.7		 1qtiA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		9 / 12 GLY A 120
GLY A 121
GLY A 122
TYR A 124
GLU A 202
SER A 203
PHE A 338
PHE A 297
HIS A 447
 None
 0.98A 1qtiA-1c2oA:
59.7		 1qtiA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 12 GLY A 205
GLU A 202
SER A 203
PHE A 295
PHE A 297
HIS A 447
 None
 1.38A 1qtiA-1c2oA:
59.7		 1qtiA-1c2oA:
58.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 6 TYR A 426
ASP A 488
ASN A 490
GLU A 450
 None
 1.13A 1rjdA-1c2oA:
undetectable		 1rjdA-1c2oA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 6 TYR A 426
ASP A 488
ASN A 490
GLU A 450
 None
 1.10A 1rjdB-1c2oA:
undetectable		 1rjdB-1c2oA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 6 TYR A 426
ASP A 488
ASN A 490
GLU A 450
 None
 1.11A 1rjdC-1c2oA:
undetectable		 1rjdC-1c2oA:
19.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1U65_A_CP0A1000_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		8 / 11 TYR A  72
TRP A  86
TYR A 124
GLU A 202
TRP A 286
LEU A 289
TYR A 341
HIS A 447
 None
 0.63A 1u65A-1c2oA:
59.4		 1u65A-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		11 / 12 ASP A  74
TRP A  86
GLY A 120
GLY A 121
GLY A 122
TYR A 124
SER A 203
PHE A 295
PHE A 297
PHE A 338
HIS A 447
 None
 0.45A 1w6rA-1c2oA:
59.5		 1w6rA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 12 GLY A 120
GLY A 121
GLY A 122
SER A 203
PHE A 297
PHE A 295
HIS A 447
 None
 1.19A 1w6rA-1c2oA:
59.5		 1w6rA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 12 GLY A 120
GLY A 121
GLY A 122
TYR A 124
SER A 203
PHE A 338
HIS A 447
 None
 0.94A 1w6rA-1c2oA:
59.5		 1w6rA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		10 / 11 ASP A  74
TRP A  86
GLY A 121
GLY A 122
TYR A 124
GLU A 202
SER A 203
PHE A 297
PHE A 338
HIS A 447
 None
 0.50A 1w76A-1c2oA:
58.6		 1w76A-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 11 GLY A 121
GLY A 122
GLU A 202
SER A 203
PHE A 297
PHE A 295
HIS A 447
 None
 1.13A 1w76A-1c2oA:
58.6		 1w76A-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 10 ASP A  74
GLY A 122
TYR A 124
SER A 203
PHE A 338
HIS A 447
 None
 1.29A 1w76B-1c2oA:
58.4		 1w76B-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		10 / 10 ASP A  74
TRP A  86
GLY A 120
GLY A 121
TYR A 124
GLU A 202
SER A 203
PHE A 297
PHE A 338
HIS A 447
 None
 0.49A 1w76B-1c2oA:
58.4		 1w76B-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 10 GLY A 120
GLY A 121
GLU A 202
SER A 203
PHE A 297
PHE A 295
HIS A 447
 None
 1.19A 1w76B-1c2oA:
58.4		 1w76B-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 12 ALA A 237
PHE A 307
GLY A 210
SER A 203
LEU A 227
 None
 0.99A 1ya4A-1c2oA:
45.9		 1ya4A-1c2oA:
36.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 4 GLY A 444
SER A 336
VAL A 331
LEU A 437
 None
 1.11A 1yajB-1c2oA:
45.3		 1yajB-1c2oA:
36.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 8 GLY A 120
GLY A 121
GLY A 122
SER A 203
ALA A 204
HIS A 447
 None
 0.38A 1yajC-1c2oA:
45.5		 1yajC-1c2oA:
36.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 8 GLY A 120
GLY A 121
SER A 203
ALA A 204
HIS A 447
 None
 1.03A 1yajC-1c2oA:
45.5		 1yajC-1c2oA:
36.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 8 GLY A 121
GLY A 122
SER A 203
ALA A 204
HIS A 447
 None
 0.74A 1yajC-1c2oA:
45.5		 1yajC-1c2oA:
36.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 0.97A 1zzrA-1c2oA:
0.0
1zzrB-1c2oA:
0.0		 1zzrA-1c2oA:
22.01
1zzrB-1c2oA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 0.99A 1zzrA-1c2oA:
0.0
1zzrB-1c2oA:
0.0		 1zzrA-1c2oA:
22.01
1zzrB-1c2oA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 0.99A 1zzuA-1c2oA:
0.0
1zzuB-1c2oA:
0.0		 1zzuA-1c2oA:
22.01
1zzuB-1c2oA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 0.96A 1zzuA-1c2oA:
0.0
1zzuB-1c2oA:
0.0		 1zzuA-1c2oA:
22.01
1zzuB-1c2oA:
22.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 9 GLY A 120
SER A 203
ALA A 204
TRP A 236
PHE A 295
HIS A 447
 None
 1.23A 2aceA-1c2oA:
59.8		 2aceA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 9 GLY A 121
GLY A 122
SER A 203
ALA A 204
PHE A 338
HIS A 447
 None
 1.03A 2aceA-1c2oA:
59.8		 2aceA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		8 / 9 GLY A 121
GLY A 122
SER A 203
ALA A 204
TRP A 236
PHE A 295
PHE A 297
HIS A 447
 None
 0.43A 2aceA-1c2oA:
59.8		 2aceA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 7 GLY A 121
GLU A 202
SER A 203
PHE A 295
HIS A 447
 None
 1.18A 2ackA-1c2oA:
60.0		 2ackA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 7 GLY A 122
TYR A 124
SER A 203
PHE A 338
HIS A 447
 None
 1.32A 2ackA-1c2oA:
60.0		 2ackA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 GLY A 230
GLU A 202
PHE A 295
HIS A 447
 None
 1.05A 2ackA-1c2oA:
60.0		 2ackA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 7 TRP A  86
GLY A 120
GLU A 202
SER A 203
HIS A 447
 None
 1.34A 2ackA-1c2oA:
60.0		 2ackA-1c2oA:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 7 TRP A  86
GLY A 121
TYR A 124
GLU A 202
SER A 203
PHE A 338
HIS A 447
 None
 0.66A 2ackA-1c2oA:
60.0		 2ackA-1c2oA:
58.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_B_GBNB914_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 10 GLU A 202
GLY A 230
THR A 231
ALA A 207
ALA A 206
 None
 1.18A 2ej3B-1c2oA:
undetectable		 2ej3B-1c2oA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 8 GLU A 202
GLY A 230
THR A 231
ALA A 207
ALA A 206
 None
 1.17A 2ej3C-1c2oA:
0.4		 2ej3C-1c2oA:
20.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		8 / 8 TYR A  72
ASP A  74
TRP A  86
TYR A 124
TRP A 286
TYR A 337
TYR A 341
HIS A 447
 None
 0.41A 2ha2A-1c2oA:
63.7		 2ha2A-1c2oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		8 / 8 TYR A  72
ASP A  74
TRP A  86
TYR A 124
TRP A 286
TYR A 337
TYR A 341
HIS A 447
 None
 0.41A 2ha2B-1c2oA:
64.2		 2ha2B-1c2oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACHA545_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 4 TYR A  72
TYR A 124
TRP A 286
TYR A 341
 None
 0.18A 2ha4A-1c2oA:
63.2		 2ha4A-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		8 / 8 TRP A  86
TYR A 124
TYR A 133
GLU A 202
TYR A 337
PHE A 338
HIS A 447
GLY A 448
 None
 0.25A 2ha4A-1c2oA:
63.2		 2ha4A-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 8 TYR A 133
GLU A 202
PHE A 295
HIS A 447
GLY A 448
 None
 0.97A 2ha4A-1c2oA:
63.2		 2ha4A-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 8 GLY A 120
ALA A 204
TRP A 236
PHE A 295
HIS A 447
 None
 1.13A 2ha4A-1c2oA:
63.2		 2ha4A-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 8 GLY A 121
ALA A 204
TRP A 236
PHE A 295
PHE A 297
 None
 1.41A 2ha4A-1c2oA:
63.2		 2ha4A-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 8 GLY A 121
GLY A 122
ALA A 204
TRP A 236
PHE A 295
PHE A 297
HIS A 447
 None
 0.24A 2ha4A-1c2oA:
63.2		 2ha4A-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_B_ACHB602_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 4 TYR A  72
TYR A 124
TRP A 286
TYR A 341
 None
 0.17A 2ha4B-1c2oA:
63.5		 2ha4B-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 7 TRP A  86
TYR A 124
TYR A 133
GLU A 202
TYR A 337
HIS A 447
GLY A 448
 None
 0.23A 2ha4B-1c2oA:
63.5		 2ha4B-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 7 GLY A 121
GLY A 122
ALA A 204
TRP A 236
PHE A 297
HIS A 447
 None
 0.26A 2ha4B-1c2oA:
63.5		 2ha4B-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA6_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		8 / 9 TYR A  72
ASP A  74
TRP A  86
TYR A 124
GLU A 202
TRP A 286
TYR A 337
TYR A 341
 None
 0.40A 2ha6A-1c2oA:
63.9		 2ha6A-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA6_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 9 TYR A  72
ASP A  74
TYR A 124
ALA A 204
TRP A 286
TYR A 341
 None
 1.12A 2ha6A-1c2oA:
63.9		 2ha6A-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		10 / 10 GLU A  81
GLU A  84
MET A  85
ASN A  87
ASP A 131
THR A 436
GLU A 452
LEU A 457
LEU A 463
TYR A 465
 None
 0.49A 2ha6A-1c2oA:
63.9		 2ha6A-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 10 GLU A  81
GLU A  84
MET A  85
ASN A  87
LEU A 463
TYR A 465
 None
 1.45A 2ha6A-1c2oA:
63.9		 2ha6A-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA6_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		9 / 9 TYR A  72
TRP A  86
TYR A 124
TRP A 286
TYR A 337
PHE A 338
TYR A 341
HIS A 447
GLY A 448
 None
 0.40A 2ha6B-1c2oA:
64.3		 2ha6B-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA6_B_SCKB952_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		10 / 10 GLU A  81
GLU A  84
MET A  85
ASN A  87
ASP A 131
THR A 436
GLU A 452
LEU A 457
LEU A 463
TYR A 465
 None
 0.46A 2ha6B-1c2oA:
64.3		 2ha6B-1c2oA:
99.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA6_B_SCKB952_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 10 GLU A  81
GLU A  84
MET A  85
ASN A  87
LEU A 463
TYR A 465
 None
 1.43A 2ha6B-1c2oA:
64.3		 2ha6B-1c2oA:
99.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		3 / 3 ARG A 247
GLN A 291
PRO A 290
 None
 0.86A 2qhfA-1c2oA:
0.0		 2qhfA-1c2oA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 THR A 103
PRO A 104
SER A  30
PRO A 108
 None
 1.07A 2v2gA-1c2oA:
undetectable
2v2gB-1c2oA:
undetectable		 2v2gA-1c2oA:
17.81
2v2gB-1c2oA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 THR A 103
PRO A 104
SER A  30
PRO A 108
 None
 1.07A 2v2gC-1c2oA:
undetectable
2v2gD-1c2oA:
undetectable		 2v2gC-1c2oA:
17.81
2v2gD-1c2oA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 THR A 103
PRO A 104
SER A  30
PRO A 108
 None
 1.08A 2v41E-1c2oA:
undetectable
2v41F-1c2oA:
undetectable		 2v41E-1c2oA:
17.81
2v41F-1c2oA:
17.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XUD_A_DMEA1544_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 6 TYR A  72
TRP A  86
TYR A 124
TRP A 286
TYR A 341
HIS A 447
 None
 0.33A 2xudA-1c2oA:
63.6		 2xudA-1c2oA:
99.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 6 TRP A 182
GLU A 185
ALA A 189
ALA A 188
 None
 1.17A 2zgwB-1c2oA:
0.0		 2zgwB-1c2oA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 1.01A 3dqrA-1c2oA:
0.0
3dqrB-1c2oA:
0.0		 3dqrA-1c2oA:
20.04
3dqrB-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 0.98A 3dqrA-1c2oA:
0.0
3dqrB-1c2oA:
0.0		 3dqrA-1c2oA:
20.04
3dqrB-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 0.97A 3jx2A-1c2oA:
0.0
3jx2B-1c2oA:
0.0		 3jx2A-1c2oA:
20.04
3jx2B-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 0.99A 3jx2A-1c2oA:
0.0
3jx2B-1c2oA:
0.0		 3jx2A-1c2oA:
20.04
3jx2B-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 0.98A 3jx3A-1c2oA:
0.0
3jx3B-1c2oA:
0.0		 3jx3A-1c2oA:
20.04
3jx3B-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 0.97A 3jx3A-1c2oA:
0.0
3jx3B-1c2oA:
0.0		 3jx3A-1c2oA:
20.04
3jx3B-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 6 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 1.05A 3jx4A-1c2oA:
0.0
3jx4B-1c2oA:
0.0		 3jx4A-1c2oA:
20.04
3jx4B-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 1.01A 3jx4A-1c2oA:
0.0
3jx4B-1c2oA:
0.0		 3jx4A-1c2oA:
20.04
3jx4B-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 1.01A 3jx5A-1c2oA:
0.0
3jx5B-1c2oA:
0.0		 3jx5A-1c2oA:
20.04
3jx5B-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 1.03A 3jx5A-1c2oA:
0.0
3jx5B-1c2oA:
0.0		 3jx5A-1c2oA:
20.04
3jx5B-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 1.03A 3jx6A-1c2oA:
0.0
3jx6B-1c2oA:
0.0		 3jx6A-1c2oA:
20.21
3jx6B-1c2oA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 0.98A 3jx6A-1c2oA:
0.0
3jx6B-1c2oA:
0.0		 3jx6A-1c2oA:
20.21
3jx6B-1c2oA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 10 VAL A 328
VAL A 326
LEU A 324
TYR A 503
GLY A 210
 None
 1.22A 3ls4H-1c2oA:
0.0		 3ls4H-1c2oA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 1.01A 3nljA-1c2oA:
0.0
3nljB-1c2oA:
0.0		 3nljA-1c2oA:
20.21
3nljB-1c2oA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 0.98A 3nljA-1c2oA:
0.0
3nljB-1c2oA:
0.0		 3nljA-1c2oA:
20.21
3nljB-1c2oA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 0.99A 3nlpA-1c2oA:
0.0
3nlpB-1c2oA:
0.1		 3nlpA-1c2oA:
20.04
3nlpB-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 0.98A 3nlpA-1c2oA:
0.0
3nlpB-1c2oA:
0.1		 3nlpA-1c2oA:
20.04
3nlpB-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 0.97A 3nlqA-1c2oA:
undetectable
3nlqB-1c2oA:
0.0		 3nlqA-1c2oA:
20.04
3nlqB-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 1.02A 3nlqA-1c2oA:
0.0
3nlqB-1c2oA:
0.0		 3nlqA-1c2oA:
20.04
3nlqB-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 0.99A 3nlrA-1c2oA:
0.0
3nlrB-1c2oA:
0.0		 3nlrA-1c2oA:
20.04
3nlrB-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 0.99A 3nlrA-1c2oA:
0.0
3nlrB-1c2oA:
0.0		 3nlrA-1c2oA:
20.04
3nlrB-1c2oA:
20.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 7 GLY A 121
GLY A 122
SER A 203
TRP A 236
HIS A 447
 None
 0.36A 3o9mA-1c2oA:
57.0		 3o9mA-1c2oA:
52.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 6 GLY A 121
GLY A 122
SER A 203
TRP A 236
HIS A 447
 None
 0.39A 3o9mB-1c2oA:
57.0		 3o9mB-1c2oA:
52.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 12 GLY A  34
VAL A  10
GLY A  19
ILE A  20
THR A 103
 None
 0.96A 3s56A-1c2oA:
undetectable		 3s56A-1c2oA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		3 / 3 SER A 512
PHE A 430
LYS A 332
 None
 1.00A 3u88A-1c2oA:
0.0		 3u88A-1c2oA:
23.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BDS_A_THAA701_1
(CHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 9 TRP A  86
GLU A 202
SER A 203
TYR A 341
TRP A 439
HIS A 447
GLY A 448
 None
 0.41A 4bdsA-1c2oA:
56.3		 4bdsA-1c2oA:
51.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 9 TRP A 182
GLY A 191
THR A 103
VAL A 147
VAL A 101
 None
 1.34A 4c9kB-1c2oA:
0.0		 4c9kB-1c2oA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 0.96A 4cx3A-1c2oA:
0.0
4cx3B-1c2oA:
0.0		 4cx3A-1c2oA:
20.04
4cx3B-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 0.97A 4cx3A-1c2oA:
0.0
4cx3B-1c2oA:
0.0		 4cx3A-1c2oA:
20.04
4cx3B-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 0.96A 4cx4A-1c2oA:
0.0
4cx4B-1c2oA:
0.0		 4cx4A-1c2oA:
20.04
4cx4B-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 0.96A 4cx4A-1c2oA:
0.0
4cx4B-1c2oA:
0.0		 4cx4A-1c2oA:
20.04
4cx4B-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_D_FOLD703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 10 ALA A 237
SER A 215
PHE A 222
ARG A 177
THR A 238
 None
 1.48A 4eilD-1c2oA:
undetectable		 4eilD-1c2oA:
22.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 12 GLY A 121
TYR A 124
SER A 125
SER A 203
PHE A 295
HIS A 447
 None
 1.44A 4ey6A-1c2oA:
63.0		 4ey6A-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		12 / 12 TRP A  86
GLY A 120
GLY A 121
GLY A 122
TYR A 124
SER A 125
SER A 203
PHE A 295
PHE A 297
TYR A 337
PHE A 338
HIS A 447
 None
 0.39A 4ey6A-1c2oA:
63.0		 4ey6A-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 12 TRP A  86
GLY A 121
SER A 203
PHE A 295
PHE A 338
HIS A 447
 None
 1.06A 4ey6A-1c2oA:
63.0		 4ey6A-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 12 GLY A 121
TYR A 124
GLU A 202
SER A 203
PHE A 295
HIS A 447
 None
 1.33A 4ey6B-1c2oA:
63.0		 4ey6B-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 12 GLY A 122
TYR A 124
GLU A 202
SER A 203
PHE A 338
HIS A 447
 None
 1.45A 4ey6B-1c2oA:
63.0		 4ey6B-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 12 GLY A 205
GLU A 202
SER A 203
PHE A 295
PHE A 297
HIS A 447
 None
 1.29A 4ey6B-1c2oA:
63.0		 4ey6B-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		12 / 12 TRP A  86
GLY A 120
GLY A 121
GLY A 122
TYR A 124
GLU A 202
SER A 203
PHE A 295
PHE A 297
TYR A 337
PHE A 338
HIS A 447
 None
 0.40A 4ey6B-1c2oA:
63.0		 4ey6B-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 12 TRP A  86
GLY A 120
PHE A 295
TYR A 337
PHE A 338
HIS A 447
 None
 1.03A 4ey6B-1c2oA:
63.0		 4ey6B-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 11 TRP A  86
GLY A 120
SER A 203
TYR A 337
HIS A 447
GLY A 448
 None
 1.26A 4ey7A-1c2oA:
62.8		 4ey7A-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 11 TYR A  72
GLY A 122
SER A 203
TRP A 286
TYR A 337
TYR A 341
HIS A 447
 None
 1.23A 4ey7A-1c2oA:
62.8		 4ey7A-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 11 TYR A  72
GLY A 122
TYR A 124
SER A 203
TRP A 286
TYR A 341
HIS A 447
 None
 1.19A 4ey7A-1c2oA:
62.8		 4ey7A-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		10 / 11 TYR A  72
TRP A  86
GLY A 121
GLU A 202
SER A 203
TRP A 286
TYR A 337
TYR A 341
HIS A 447
GLY A 448
 None
 0.74A 4ey7A-1c2oA:
62.8		 4ey7A-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		10 / 11 TYR A  72
TRP A  86
GLY A 121
TYR A 124
GLU A 202
SER A 203
TRP A 286
TYR A 341
HIS A 447
GLY A 448
 None
 0.57A 4ey7A-1c2oA:
62.8		 4ey7A-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 11 TRP A  86
GLY A 120
SER A 203
TYR A 337
HIS A 447
GLY A 448
 None
 1.28A 4ey7B-1c2oA:
62.8		 4ey7B-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 11 TYR A  72
GLY A 122
SER A 203
TRP A 286
TYR A 337
TYR A 341
HIS A 447
 None
 1.26A 4ey7B-1c2oA:
62.8		 4ey7B-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 11 TYR A  72
GLY A 122
TYR A 124
SER A 203
TRP A 286
TYR A 341
HIS A 447
 None
 1.22A 4ey7B-1c2oA:
62.8		 4ey7B-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		10 / 11 TYR A  72
TRP A  86
GLY A 121
GLU A 202
SER A 203
TRP A 286
TYR A 337
TYR A 341
HIS A 447
GLY A 448
 None
 0.77A 4ey7B-1c2oA:
62.8		 4ey7B-1c2oA:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		10 / 11 TYR A  72
TRP A  86
GLY A 121
TYR A 124
GLU A 202
SER A 203
TRP A 286
TYR A 341
HIS A 447
GLY A 448
 None
 0.59A 4ey7B-1c2oA:
62.8		 4ey7B-1c2oA:
88.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 5 HIS A 447
TYR A 124
GLY A 121
SER A 203
 None
 1.29A 4fu8A-1c2oA:
undetectable		 4fu8A-1c2oA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 5 HIS A 447
TYR A 124
GLY A 122
SER A 203
 None
 1.28A 4fu8A-1c2oA:
undetectable		 4fu8A-1c2oA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 6 ASN A 514
GLU A 519
TYR A 428
GLU A 431
 None
 1.03A 4mi4A-1c2oA:
1.7		 4mi4A-1c2oA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 ASN A 514
GLU A 519
TYR A 428
GLU A 431
 None
 1.05A 4mi4B-1c2oA:
0.0
4mi4C-1c2oA:
1.5		 4mi4B-1c2oA:
13.75
4mi4C-1c2oA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 ASN A 514
GLU A 519
TYR A 428
GLU A 431
 None
 1.02A 4mi4A-1c2oA:
1.7
4mi4C-1c2oA:
1.0		 4mi4A-1c2oA:
13.75
4mi4C-1c2oA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 TYR A 465
GLU A 452
TYR A 449
GLU A  81
 None
 1.17A 4mi4A-1c2oA:
1.7
4mi4C-1c2oA:
1.0		 4mi4A-1c2oA:
13.75
4mi4C-1c2oA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 ASN A 514
GLU A 519
TYR A 428
GLU A 431
 None
 1.03A 4mj8A-1c2oA:
0.0
4mj8C-1c2oA:
1.4		 4mj8A-1c2oA:
13.79
4mj8C-1c2oA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 ASN A 514
GLU A 519
TYR A 428
GLU A 431
 None
 1.03A 4mj8B-1c2oA:
1.6
4mj8C-1c2oA:
1.4		 4mj8B-1c2oA:
13.79
4mj8C-1c2oA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 ASN A 514
GLU A 519
TYR A 428
GLU A 431
 None
 1.16A 4mj8C-1c2oA:
1.4		 4mj8C-1c2oA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 12 ALA A 427
GLN A 413
ALA A 420
ILE A 316
ASN A 233
 None
 1.19A 4r3aA-1c2oA:
undetectable		 4r3aA-1c2oA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 HIS A 393
ASP A 396
SER A 399
ARG A 395
 None
 1.07A 4uhxA-1c2oA:
0.0		 4uhxA-1c2oA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 HIS A 393
ASP A 396
SER A 399
ARG A 395
 None
 1.07A 4uhxA-1c2oA:
0.0		 4uhxA-1c2oA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 11 ASN A 170
SER A 208
GLY A 210
PHE A 307
THR A 238
 None
 1.21A 4xt7A-1c2oA:
0.7		 4xt7A-1c2oA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 6 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 0.99A 5addA-1c2oA:
0.0
5addB-1c2oA:
0.0		 5addA-1c2oA:
20.04
5addB-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 0.99A 5addA-1c2oA:
0.0
5addB-1c2oA:
0.0		 5addA-1c2oA:
20.04
5addB-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 6 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 1.06A 5adeA-1c2oA:
0.0
5adeB-1c2oA:
0.0		 5adeA-1c2oA:
20.04
5adeB-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 1.09A 5adeA-1c2oA:
0.0
5adeB-1c2oA:
0.0		 5adeA-1c2oA:
20.04
5adeB-1c2oA:
20.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E2I_A_DMEA605_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 6 TYR A  72
ASP A  74
TYR A 124
TRP A 286
TYR A 341
 None
 0.54A 5e2iA-1c2oA:
59.3		 5e2iA-1c2oA:
58.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E4J_A_DMEA608_1
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		8 / 9 TYR A  72
TRP A  86
TYR A 124
GLU A 202
TRP A 286
TYR A 341
HIS A 447
GLY A 448
 None
 0.56A 5e4jA-1c2oA:
59.1		 5e4jA-1c2oA:
58.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 VAL A 326
ARG A 219
VAL A 209
PHE A 222
 None
 1.01A 5g0pA-1c2oA:
0.0
5g0pB-1c2oA:
0.0		 5g0pA-1c2oA:
20.04
5g0pB-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 PHE A 222
VAL A 326
ARG A 219
VAL A 209
 None
 1.02A 5g0pA-1c2oA:
0.0
5g0pB-1c2oA:
0.0		 5g0pA-1c2oA:
20.04
5g0pB-1c2oA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 12 PRO A 489
VAL A 326
ALA A 412
ALA A 415
LEU A 524
GLY A 523
 None
 1.48A 5igtA-1c2oA:
0.0		 5igtA-1c2oA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 10 LEU A 308
PRO A 232
ALA A 207
PHE A 123
VAL A 300
 None
 1.34A 5m0oA-1c2oA:
undetectable		 5m0oA-1c2oA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 10 GLY A 191
LEU A 115
VAL A 147
LEU A 146
THR A 103
 None
 1.04A 5o96G-1c2oA:
undetectable
5o96H-1c2oA:
undetectable		 5o96G-1c2oA:
19.26
5o96H-1c2oA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 10 GLY A 192
LEU A 138
VAL A 147
LEU A 146
THR A 103
ALA A 139
 None
 1.34A 5o96G-1c2oA:
undetectable
5o96H-1c2oA:
undetectable		 5o96G-1c2oA:
19.26
5o96H-1c2oA:
19.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 7 ASP A  74
THR A  75
LEU A  76
THR A  83
TYR A 337
 None
 1.13A 5ov9A-1c2oA:
63.5		 5ov9A-1c2oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 7 TYR A  72
ASP A  74
THR A  75
LEU A  76
THR A  83
 None
 0.90A 5ov9A-1c2oA:
63.5		 5ov9A-1c2oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 7 TYR A  72
ASP A  74
THR A  83
VAL A 340
TYR A 341
 None
 0.83A 5ov9A-1c2oA:
63.5		 5ov9A-1c2oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OV9_A_CVIA609_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 6 TYR A  72
TYR A 124
ASP A 283
TRP A 286
HIS A 287
TYR A 341
 None
 0.53A 5ov9A-1c2oA:
63.5		 5ov9A-1c2oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OV9_B_CVIB602_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 ASP A  74
THR A  75
LEU A  76
TYR A  77
 None
 0.70A 5ov9B-1c2oA:
64.0		 5ov9B-1c2oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OV9_B_CVIB602_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 ASP A  74
THR A  75
LEU A  76
TYR A 337
 None
 0.98A 5ov9B-1c2oA:
64.0		 5ov9B-1c2oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OV9_B_CVIB602_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 ASP A  74
THR A  75
TYR A  77
THR A  83
 None
 0.46A 5ov9B-1c2oA:
64.0		 5ov9B-1c2oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OV9_B_CVIB602_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 TYR A  72
ASP A  74
THR A  75
LEU A  76
 None
 0.60A 5ov9B-1c2oA:
64.0		 5ov9B-1c2oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		7 / 7 TYR A  72
TYR A 124
GLN A 279
ASP A 283
TRP A 286
HIS A 287
TYR A 341
 None
 0.54A 5ov9B-1c2oA:
64.0		 5ov9B-1c2oA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		3 / 3 VAL A 511
VAL A 520
GLN A 499
 None
 0.71A 5qguA-1c2oA:
0.0		 5qguA-1c2oA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		3 / 3 VAL A 511
VAL A 520
GLN A 499
 None
 0.70A 5qh9A-1c2oA:
0.0		 5qh9A-1c2oA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		3 / 3 VAL A 511
VAL A 520
GLN A 499
 None
 0.65A 5qhaA-1c2oA:
0.0		 5qhaA-1c2oA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		3 / 3 VAL A 511
VAL A 520
GLN A 499
 None
 0.72A 5qhfA-1c2oA:
0.0		 5qhfA-1c2oA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 6 ASN A 170
PRO A  49
VAL A 171
ASP A 304
 None
 1.14A 5umd2-1c2oA:
0.0
5umdF-1c2oA:
undetectable		 5umd2-1c2oA:
10.75
5umdF-1c2oA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 ALA A 237
VAL A 300
SER A 298
GLY A 122
 None
 0.92A 5v0vA-1c2oA:
2.2		 5v0vA-1c2oA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 ASP A 134
TYR A 133
HIS A 432
LEU A 146
 None
 1.11A 5x1bA-1c2oA:
0.2
5x1bC-1c2oA:
0.2
5x1bP-1c2oA:
0.1		 5x1bA-1c2oA:
23.41
5x1bC-1c2oA:
17.50
5x1bP-1c2oA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		3 / 3 GLU A 450
TRP A 117
HIS A 447
 None
 0.93A 5xipA-1c2oA:
0.0		 5xipA-1c2oA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_G_6ELG501_0
(PROTEIN CEREBLON)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 HIS A 393
PHE A 346
HIS A 381
THR A 528
 None
 1.24A 5yj1G-1c2oA:
0.0
5yj1Y-1c2oA:
undetectable		 5yj1G-1c2oA:
11.09
5yj1Y-1c2oA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		3 / 3 GLU A 519
LEU A 518
ARG A 475
 None
 0.74A 6d8fA-1c2oA:
2.0		 6d8fA-1c2oA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EP4_A_DMEA601_1
(CHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		5 / 5 TRP A  86
TYR A 133
GLU A 202
TYR A 341
HIS A 447
 None
 0.34A 6ep4A-1c2oA:
57.5		 6ep4A-1c2oA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 GLY A 121
SER A 203
PHE A 338
TYR A 341
 None
 1.02A 6eqpA-1c2oA:
56.6		 6eqpA-1c2oA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		6 / 8 TRP A  86
GLY A 122
SER A 203
TRP A 236
PHE A 338
TYR A 341
 None
 0.43A 6eqpA-1c2oA:
56.6		 6eqpA-1c2oA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		3 / 3 LEU A 199
GLY A 201
PHE A 123
 None
 0.66A 6exiC-1c2oA:
3.4		 6exiC-1c2oA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 8 LEU A 146
ASP A 134
TYR A 133
HIS A 432
 None
 1.17A 6nknC-1c2oA:
0.1
6nknN-1c2oA:
0.0
6nknP-1c2oA:
0.0		 6nknC-1c2oA:
17.50
6nknN-1c2oA:
23.41
6nknP-1c2oA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1c2o ACETYLCHOLINESTERASE
(Electrophorus
electricus) 		4 / 7 ASP A 134
TYR A 133
HIS A 432
LEU A 146
 None
 1.19A 6nmfA-1c2oA:
undetectable
6nmfC-1c2oA:
0.0
6nmfP-1c2oA:
0.1		 6nmfA-1c2oA:
23.41
6nmfC-1c2oA:
17.50
6nmfP-1c2oA:
17.50