SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c3l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		3 / 3 THR A 211
THR A 213
PRO A 210
 None
 0.86A 1a7yA-1c3lA:
undetectable		 1a7yA-1c3lA:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		3 / 3 THR A 213
PRO A 210
THR A 211
 None
 0.85A 1i3wE-1c3lA:
undetectable		 1i3wE-1c3lA:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		3 / 3 THR A 211
THR A 213
PRO A 210
 None
 0.85A 1i3wE-1c3lA:
undetectable		 1i3wE-1c3lA:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		3 / 3 THR A 211
THR A 213
PRO A 210
 None
 0.83A 1i3wF-1c3lA:
undetectable		 1i3wF-1c3lA:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		3 / 3 THR A 211
THR A 213
PRO A 210
 None
 0.87A 1i3wH-1c3lA:
undetectable		 1i3wH-1c3lA:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		3 / 3 THR A 213
PRO A 210
THR A 211
 None
 0.83A 1mnvD-1c3lA:
undetectable		 1mnvD-1c3lA:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		3 / 3 THR A 211
THR A 213
PRO A 210
 None
 0.82A 1mnvD-1c3lA:
undetectable		 1mnvD-1c3lA:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		3 / 3 THR A 213
PRO A 210
THR A 211
 None
 0.81A 1ovfB-1c3lA:
undetectable		 1ovfB-1c3lA:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		3 / 3 THR A 211
THR A 213
PRO A 210
 None
 0.83A 1qfiA-1c3lA:
undetectable		 1qfiA-1c3lA:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		4 / 6 VAL A 192
GLU A 195
LEU A 196
PHE A 261
 None
 1.10A 1s8fB-1c3lA:
2.9		 1s8fB-1c3lA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		4 / 6 SER A 191
ILE A 165
ALA A 176
ALA A 223
 None
None
CA  A 284 ( 4.3A)
None
 0.77A 1w0gA-1c3lA:
undetectable		 1w0gA-1c3lA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_B_CLUB809_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		4 / 6 ALA A 129
TYR A 167
MET A 135
TYR A 104
 None
 1.39A 2pncB-1c3lA:
undetectable		 2pncB-1c3lA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_A_DAHA2_1
(RANASMURFIN)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 9 ALA A 151
ALA A 153
SER A 190
SER A 224
ALA A 223
 None
 1.26A 2vh3A-1c3lA:
undetectable		 2vh3A-1c3lA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		4 / 7 TYR A 171
SER A 173
GLN A 137
ILE A 111
 None
 1.08A 2xz5A-1c3lA:
0.0
2xz5B-1c3lA:
0.0		 2xz5A-1c3lA:
22.39
2xz5B-1c3lA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		4 / 8 TYR A 171
SER A 173
GLN A 137
ILE A 111
 None
 1.04A 2xz5B-1c3lA:
0.0
2xz5E-1c3lA:
0.0		 2xz5B-1c3lA:
22.39
2xz5E-1c3lA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 12 ILE A 268
GLY A 264
GLY A 266
ALA A 200
PHE A 261
 None
 1.16A 2yvlB-1c3lA:
2.6		 2yvlB-1c3lA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 12 SER A  98
GLY A  65
THR A  66
LEU A  31
VAL A  30
 None
 1.17A 2zifB-1c3lA:
undetectable		 2zifB-1c3lA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		4 / 7 GLY A 229
ILE A  11
VAL A 270
GLN A  17
 None
 0.87A 3fi0E-1c3lA:
undetectable		 3fi0E-1c3lA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		4 / 8 GLY A 229
ILE A  11
VAL A 270
GLN A  17
 None
 0.77A 3fi0G-1c3lA:
undetectable		 3fi0G-1c3lA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		4 / 8 GLY A 229
ILE A  11
VAL A 270
GLN A  17
 None
 0.81A 3fi0I-1c3lA:
undetectable		 3fi0I-1c3lA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 9 GLY A 229
VAL A  72
ILE A  11
VAL A 270
GLN A  17
 None
 1.15A 3fi0O-1c3lA:
undetectable		 3fi0O-1c3lA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 9 GLY A 229
VAL A  72
ILE A  11
VAL A 270
GLN A  17
 None
 1.18A 3fi0R-1c3lA:
undetectable		 3fi0R-1c3lA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 12 ALA A  73
GLY A  83
LEU A  42
SER A  87
GLY A  23
 None
 1.08A 3g2oB-1c3lA:
2.4		 3g2oB-1c3lA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 12 GLY A  70
GLY A  83
ILE A  35
ASP A  41
LEU A  42
 None
None
None
CA  A 282 (-2.2A)
None
 1.04A 3ihtA-1c3lA:
2.7		 3ihtA-1c3lA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 10 LEU A 267
ILE A  11
PRO A   9
SER A 182
GLY A   7
 None
 1.41A 3ijxB-1c3lA:
0.0
3ijxD-1c3lA:
0.3		 3ijxB-1c3lA:
22.53
3ijxD-1c3lA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 XE  A 281 ( 3.9A)
None
None
None
None
 1.04A 3ln1A-1c3lA:
undetectable		 3ln1A-1c3lA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 XE  A 281 ( 3.9A)
None
None
None
None
 1.03A 3ln1B-1c3lA:
undetectable		 3ln1B-1c3lA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 XE  A 281 ( 3.9A)
None
None
None
None
 1.04A 3ln1C-1c3lA:
undetectable		 3ln1C-1c3lA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 XE  A 281 ( 3.9A)
None
None
None
None
 1.03A 3ln1D-1c3lA:
undetectable		 3ln1D-1c3lA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 10 ALA A 176
LEU A 250
ALA A 231
VAL A  84
THR A  71
 CA  A 284 ( 4.3A)
None
None
None
None
 1.20A 3r9cA-1c3lA:
undetectable		 3r9cA-1c3lA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 12 GLY A   7
GLY A  83
ALA A 230
ALA A 232
SER A 236
 None
 1.09A 3sudA-1c3lA:
undetectable		 3sudA-1c3lA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_1
(HIV-1 PROTEASE)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		4 / 7 LEU A  90
ALA A  85
VAL A  26
ILE A 268
 None
 0.97A 4eyrA-1c3lA:
0.0		 4eyrA-1c3lA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 12 ALA A 176
ASN A 163
ALA A 194
GLY A 193
LEU A 196
 CA  A 284 ( 4.3A)
None
None
None
None
 0.91A 4oaeA-1c3lA:
undetectable		 4oaeA-1c3lA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 12 GLY A 229
ALA A 228
VAL A 150
LEU A 250
ILE A  11
 None
 1.23A 4pd9A-1c3lA:
0.0		 4pd9A-1c3lA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 12 THR A  59
GLN A  36
GLY A  61
THR A 211
SER A  99
 None
 1.35A 5hfjC-1c3lA:
undetectable		 5hfjC-1c3lA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 XE  A 281 ( 3.9A)
None
None
None
None
 1.01A 5kirA-1c3lA:
undetectable		 5kirA-1c3lA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 12 ALA A 152
VAL A  68
GLY A  70
ALA A  69
LEU A  90
 XE  A 281 ( 3.9A)
None
None
None
None
 1.04A 5kirB-1c3lA:
0.0		 5kirB-1c3lA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 8 VAL A 246
ILE A 234
ALA A 230
VAL A 150
VAL A 148
 None
 1.16A 5l94A-1c3lA:
0.0		 5l94A-1c3lA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 8 VAL A 246
ILE A 234
ALA A 232
VAL A 150
VAL A 148
 None
 1.25A 5l94A-1c3lA:
0.0		 5l94A-1c3lA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0I_A_TRPA402_0
(TRYPTOPHAN--TRNA
LIGASE)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 9 GLY A 229
VAL A  72
ILE A  11
VAL A 270
GLN A  17
 None
 1.20A 5v0iA-1c3lA:
undetectable		 5v0iA-1c3lA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0I_B_TRPB402_0
(TRYPTOPHAN--TRNA
LIGASE)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 9 GLY A 229
VAL A  72
ILE A  11
VAL A 270
GLN A  17
 None
 1.22A 5v0iB-1c3lA:
undetectable		 5v0iB-1c3lA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		3 / 3 GLY A 166
VAL A 139
MET A 135
 None
 0.58A 5ycpA-1c3lA:
0.0		 5ycpA-1c3lA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		5 / 11 GLY A 229
ALA A 230
ALA A  85
PRO A  86
VAL A  28
 None
 1.12A 5yk2A-1c3lA:
0.0		 5yk2A-1c3lA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		4 / 5 ALA A 134
SER A 132
GLY A 131
TYR A 171
 None
 1.16A 5yodB-1c3lA:
0.0		 5yodB-1c3lA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		4 / 5 ALA A 134
SER A 132
GLY A 131
TYR A 171
 None
 1.19A 5yodD-1c3lA:
undetectable		 5yodD-1c3lA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		4 / 8 ILE A 107
PRO A 168
ALA A 114
THR A 115
 None
 0.90A 6cduD-1c3lA:
0.0
6cduE-1c3lA:
0.0		 6cduD-1c3lA:
25.21
6cduE-1c3lA:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		4 / 4 HIS A 238
VAL A 246
LEU A 241
ALA A 274
 None
 1.26A 6d8pB-1c3lA:
3.0		 6d8pB-1c3lA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 1c3l SUBTILISIN-CARLSBERG
(Bacillus
licheniformis) 		4 / 5 GLN A   2
THR A   3
HIS A  67
GLY A  83
 CA  A 282 (-3.3A)
None
None
None
 1.19A 6gbnC-1c3lA:
2.9		 6gbnC-1c3lA:
22.59