SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c3n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 1c3n AGGLUTININ
(Helianthus
tuberosus) 		5 / 12 PHE A 130
ILE A  44
PHE A  46
GLY A  84
LEU A 120
 None
 1.25A 2lbdA-1c3nA:
undetectable		 2lbdA-1c3nA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 1c3n AGGLUTININ
(Helianthus
tuberosus) 		3 / 3 ASP A  66
THR A  99
GLU A  69
 None
 0.72A 2zifB-1c3nA:
undetectable		 2zifB-1c3nA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1c3n AGGLUTININ
(Helianthus
tuberosus) 		5 / 11 ILE A  30
ALA A  81
ILE A  82
ILE A  35
PHE A 130
 None
 1.14A 3b2rB-1c3nA:
undetectable		 3b2rB-1c3nA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 1c3n AGGLUTININ
(Helianthus
tuberosus) 		4 / 8 ILE A 141
ILE A  33
SER A 119
THR A 102
 None
 0.81A 3ua5A-1c3nA:
0.0		 3ua5A-1c3nA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 1c3n AGGLUTININ
(Helianthus
tuberosus) 		5 / 12 PRO A 109
GLY A  84
ILE A  41
PHE A 130
PHE A 110
 None
 1.03A 5fa8A-1c3nA:
undetectable		 5fa8A-1c3nA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1c3n AGGLUTININ
(Helianthus
tuberosus) 		5 / 12 ILE A  71
GLY A 108
ALA A  68
ILE A 141
PHE A 130
 None
 1.13A 5ih0A-1c3nA:
undetectable		 5ih0A-1c3nA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1c3n AGGLUTININ
(Helianthus
tuberosus) 		5 / 12 ILE A  82
LEU A  98
SER A  58
GLY A 129
GLY A 143
 None
 1.00A 5l6eA-1c3nA:
undetectable		 5l6eA-1c3nA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1c3n AGGLUTININ
(Helianthus
tuberosus) 		5 / 12 ILE A 141
GLY A 142
VAL A 144
VAL A 145
ILE A  35
 None
 1.05A 5n4iA-1c3nA:
undetectable		 5n4iA-1c3nA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1c3n AGGLUTININ
(Helianthus
tuberosus) 		5 / 10 ILE A 141
GLY A 142
GLY A  11
SER A 116
VAL A  95
 None
 1.08A 5twjB-1c3nA:
undetectable		 5twjB-1c3nA:
21.55