SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c3x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 7 GLY A 118
ALA A  25
THR A 125
THR A  82
None
0.71A 1c9sT-1c3xA:
undetectable
1c9sU-1c3xA:
undetectable
1c9sT-1c3xA:
14.98
1c9sU-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 GLY A 118
ALA A  25
THR A 125
THR A  82
None
0.69A 1c9sU-1c3xA:
undetectable
1c9sV-1c3xA:
undetectable
1c9sU-1c3xA:
14.98
1c9sV-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 7 SER A  84
THR A  33
VAL A  35
ALA A  26
None
1.05A 1fo4B-1c3xA:
undetectable
1fo4B-1c3xA:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 7 GLY A 118
ALA A  25
THR A 125
THR A  82
None
0.69A 1gtfL-1c3xA:
undetectable
1gtfM-1c3xA:
undetectable
1gtfL-1c3xA:
14.98
1gtfM-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 GLY A 118
ALA A  25
THR A 125
THR A  82
None
0.69A 1gtfN-1c3xA:
undetectable
1gtfO-1c3xA:
undetectable
1gtfN-1c3xA:
14.98
1gtfO-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 7 GLY A 118
ALA A  25
THR A 125
THR A  82
None
0.72A 1gtnA-1c3xA:
undetectable
1gtnK-1c3xA:
undetectable
1gtnA-1c3xA:
14.98
1gtnK-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 THR A  82
GLY A 118
ALA A  25
THR A 125
None
0.72A 1gtnA-1c3xA:
0.0
1gtnB-1c3xA:
undetectable
1gtnA-1c3xA:
14.98
1gtnB-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 GLY A 118
ALA A  25
THR A 125
THR A  82
None
0.71A 1gtnP-1c3xA:
undetectable
1gtnQ-1c3xA:
undetectable
1gtnP-1c3xA:
14.98
1gtnQ-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
3 / 3 THR A 189
LEU A 190
LEU A 151
None
0.66A 1mz9C-1c3xA:
undetectable
1mz9C-1c3xA:
11.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
6 / 10 GLY A 137
GLU A 204
VAL A 220
GLY A 221
MET A 222
THR A 245
8IG  A 306 (-3.3A)
8IG  A 306 (-2.8A)
8IG  A 306 (-4.6A)
8IG  A 306 (-3.4A)
8IG  A 306 (-4.0A)
8IG  A 306 (-3.0A)
0.61A 1pwyE-1c3xA:
30.6
1pwyE-1c3xA:
35.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 GLY A 118
ALA A  25
THR A 125
THR A  82
None
0.74A 1utdB-1c3xA:
undetectable
1utdC-1c3xA:
undetectable
1utdB-1c3xA:
14.98
1utdC-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 GLY A 118
ALA A  25
THR A 125
THR A  82
None
0.71A 1utdF-1c3xA:
0.0
1utdG-1c3xA:
undetectable
1utdF-1c3xA:
14.98
1utdG-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 GLY A 118
ALA A  25
THR A 125
THR A  82
None
0.71A 1utdI-1c3xA:
undetectable
1utdJ-1c3xA:
undetectable
1utdI-1c3xA:
14.98
1utdJ-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 GLY A 118
ALA A  25
THR A 125
THR A  82
None
0.72A 1utdJ-1c3xA:
undetectable
1utdK-1c3xA:
0.0
1utdJ-1c3xA:
14.98
1utdK-1c3xA:
14.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
6 / 10 GLY A 137
GLU A 204
VAL A 220
GLY A 221
MET A 222
THR A 245
8IG  A 306 (-3.3A)
8IG  A 306 (-2.8A)
8IG  A 306 (-4.6A)
8IG  A 306 (-3.4A)
8IG  A 306 (-4.0A)
8IG  A 306 (-3.0A)
0.49A 1v3qE-1c3xA:
30.5
1v3qE-1c3xA:
35.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
5 / 10 LEU A 247
ALA A 249
ILE A 251
VAL A 220
ALA A 196
None
None
None
8IG  A 306 (-4.6A)
None
1.18A 1xp0A-1c3xA:
undetectable
1xp0A-1c3xA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 7 ARG A 232
GLU A 227
ALA A 123
ALA A 122
None
1.02A 2ejfA-1c3xA:
undetectable
2ejfA-1c3xA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
5 / 9 ALA A  97
VAL A  99
VAL A  87
GLY A  56
ALA A 280
None
0.97A 2z0yB-1c3xA:
undetectable
2z0yB-1c3xA:
26.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
5 / 6 GLY A 137
TYR A 203
GLU A 204
GLY A 221
MET A 222
8IG  A 306 (-3.3A)
8IG  A 306 (-4.4A)
8IG  A 306 (-2.8A)
8IG  A 306 (-3.4A)
8IG  A 306 (-4.0A)
0.46A 3e9rA-1c3xA:
30.5
3e9rA-1c3xA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 6 GLY A 221
TYR A 203
GLU A 204
GLY A 200
8IG  A 306 (-3.4A)
8IG  A 306 (-4.4A)
8IG  A 306 (-2.8A)
None
1.07A 3e9rA-1c3xA:
30.5
3e9rA-1c3xA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
5 / 6 GLY A 137
TYR A 203
GLU A 204
GLY A 221
MET A 222
8IG  A 306 (-3.3A)
8IG  A 306 (-4.4A)
8IG  A 306 (-2.8A)
8IG  A 306 (-3.4A)
8IG  A 306 (-4.0A)
0.48A 3e9rC-1c3xA:
30.6
3e9rC-1c3xA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 6 GLY A 221
TYR A 203
GLU A 204
GLY A 200
8IG  A 306 (-3.4A)
8IG  A 306 (-4.4A)
8IG  A 306 (-2.8A)
None
1.08A 3e9rC-1c3xA:
30.6
3e9rC-1c3xA:
33.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 GLY A 216
ALA A 217
ASP A 218
THR A 225
None
0.64A 3el0A-1c3xA:
undetectable
3el0A-1c3xA:
17.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
8 / 12 SER A  46
TYR A 107
GLY A 137
TYR A 203
GLU A 204
VAL A 220
GLY A 221
MET A 222
PO4  A 303 (-3.9A)
None
8IG  A 306 (-3.3A)
8IG  A 306 (-4.4A)
8IG  A 306 (-2.8A)
8IG  A 306 (-4.6A)
8IG  A 306 (-3.4A)
8IG  A 306 (-4.0A)
0.71A 3f8wA-1c3xA:
30.8
3f8wA-1c3xA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
9 / 12 SER A  46
HIS A 105
TYR A 107
GLY A 137
TYR A 203
GLU A 204
VAL A 220
GLY A 221
MET A 222
PO4  A 303 (-3.9A)
PO4  A 303 (-4.2A)
None
8IG  A 306 (-3.3A)
8IG  A 306 (-4.4A)
8IG  A 306 (-2.8A)
8IG  A 306 (-4.6A)
8IG  A 306 (-3.4A)
8IG  A 306 (-4.0A)
0.71A 3f8wB-1c3xA:
30.7
3f8wB-1c3xA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
5 / 12 HIS A 154
TYR A 175
ALA A 230
GLY A 235
VAL A 119
None
1.20A 3f8wC-1c3xA:
30.9
3f8wC-1c3xA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
9 / 12 SER A  46
HIS A 105
TYR A 107
GLY A 137
TYR A 203
GLU A 204
VAL A 220
GLY A 221
MET A 222
PO4  A 303 (-3.9A)
PO4  A 303 (-4.2A)
None
8IG  A 306 (-3.3A)
8IG  A 306 (-4.4A)
8IG  A 306 (-2.8A)
8IG  A 306 (-4.6A)
8IG  A 306 (-3.4A)
8IG  A 306 (-4.0A)
0.70A 3f8wC-1c3xA:
30.9
3f8wC-1c3xA:
33.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
5 / 12 LEU A 275
ALA A 277
GLY A 269
ILE A 279
ARG A  83
None
1.29A 3gyqA-1c3xA:
undetectable
3gyqB-1c3xA:
undetectable
3gyqA-1c3xA:
24.37
3gyqB-1c3xA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
5 / 10 ILE A 131
ALA A  97
LEU A 276
LEU A  55
VAL A  87
None
1.16A 3o02A-1c3xA:
undetectable
3o02B-1c3xA:
0.0
3o02A-1c3xA:
22.67
3o02B-1c3xA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
5 / 9 ILE A  67
GLY A  69
PHE A  70
THR A 121
GLY A 118
None
1.26A 4acaB-1c3xA:
3.9
4acaC-1c3xA:
3.0
4acaB-1c3xA:
19.29
4acaC-1c3xA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 THR A 121
LEU A 100
GLY A 101
THR A  64
None
0.80A 4c9nA-1c3xA:
undetectable
4c9nA-1c3xA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 7 LEU A  98
THR A  82
ILE A  67
GLY A 118
None
0.86A 4eqlA-1c3xA:
undetectable
4eqlA-1c3xA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 7 LEU A  98
THR A  82
ILE A  67
GLY A 118
None
0.91A 4eqlB-1c3xA:
undetectable
4eqlB-1c3xA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
5 / 12 PHE A  70
LEU A 100
ALA A  97
ALA A 122
THR A 125
None
1.26A 4fiaA-1c3xA:
0.0
4fiaA-1c3xA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
5 / 12 PHE A  70
LEU A 100
ALA A  97
ALA A 122
THR A 125
None
1.26A 4fiaA-1c3xA:
0.0
4fiaA-1c3xA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 4 ALA A 122
VAL A  43
GLY A 101
THR A  82
None
1.11A 4ubeA-1c3xA:
2.5
4ubeA-1c3xA:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
5 / 11 LEU A  42
LEU A 275
LEU A 276
ILE A 279
LEU A 190
None
0.94A 4zowA-1c3xA:
0.0
4zowA-1c3xA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 THR A  82
GLY A 118
ALA A  25
THR A 125
None
0.68A 5eevL-1c3xA:
undetectable
5eevV-1c3xA:
undetectable
5eevL-1c3xA:
14.98
5eevV-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 THR A  82
GLY A 118
ALA A  25
THR A 125
None
0.68A 5eewL-1c3xA:
undetectable
5eewV-1c3xA:
undetectable
5eewL-1c3xA:
14.98
5eewV-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 THR A  82
GLY A 118
ALA A  25
THR A 125
None
0.68A 5eezL-1c3xA:
undetectable
5eezV-1c3xA:
undetectable
5eezL-1c3xA:
14.98
5eezV-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 THR A  82
GLY A 118
ALA A  25
THR A 125
None
0.68A 5ef1L-1c3xA:
undetectable
5ef1V-1c3xA:
undetectable
5ef1L-1c3xA:
14.98
5ef1V-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 THR A  82
GLY A 118
ALA A  25
THR A 125
None
0.68A 5ef2L-1c3xA:
undetectable
5ef2V-1c3xA:
undetectable
5ef2L-1c3xA:
14.98
5ef2V-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 THR A  82
GLY A 118
ALA A  25
THR A 125
None
0.68A 5ef3L-1c3xA:
undetectable
5ef3V-1c3xA:
undetectable
5ef3L-1c3xA:
14.98
5ef3V-1c3xA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 7 THR A 133
THR A 224
VAL A 174
TYR A 175
None
1.11A 5ov9A-1c3xA:
undetectable
5ov9A-1c3xA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB602_0
(ACETYLCHOLINESTERASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 THR A 133
LEU A 132
VAL A 174
TYR A 175
None
1.21A 5ov9B-1c3xA:
1.8
5ov9B-1c3xA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB602_0
(ACETYLCHOLINESTERASE)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 THR A 133
THR A 224
VAL A 174
TYR A 175
None
1.11A 5ov9B-1c3xA:
1.8
5ov9B-1c3xA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)
1c3x PENTOSYLTRANSFERASE
(Cellulomonas
sp.)
4 / 8 GLY A 213
LEU A 215
VAL A 194
LEU A 157
None
0.83A 6czmD-1c3xA:
0.0
6czmF-1c3xA:
1.0
6czmD-1c3xA:
21.61
6czmF-1c3xA:
21.61