SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c41'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		8 / 12 TRP A  25
GLY A  58
SER A  59
TRP A  60
GLU A  61
LEU A 120
HIS A 127
ILE A 131
 LMZ  A 201 (-3.5A)
LMZ  A 201 (-2.9A)
LMZ  A 201 (-2.5A)
None
LMZ  A 201 (-2.6A)
LMZ  A 201 (-3.8A)
LMZ  A 201 ( 3.8A)
LMZ  A 201 (-4.3A)
 0.62A 1kyvA-1c41A:
26.7
1kyvE-1c41A:
27.6		 1kyvA-1c41A:
47.50
1kyvE-1c41A:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KYV_B_RBFB502_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		7 / 11 TRP A  25
GLY A  58
SER A  59
TRP A  60
GLU A  61
LEU A 120
HIS A 127
 LMZ  A 201 (-3.5A)
LMZ  A 201 (-2.9A)
LMZ  A 201 (-2.5A)
None
LMZ  A 201 (-2.6A)
LMZ  A 201 (-3.8A)
LMZ  A 201 ( 3.8A)
 0.47A 1kyvA-1c41A:
26.7
1kyvB-1c41A:
26.7		 1kyvA-1c41A:
47.50
1kyvB-1c41A:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		8 / 12 TRP A  25
GLY A  58
SER A  59
TRP A  60
GLU A  61
LEU A 120
HIS A 127
ILE A 131
 LMZ  A 201 (-3.5A)
LMZ  A 201 (-2.9A)
LMZ  A 201 (-2.5A)
None
LMZ  A 201 (-2.6A)
LMZ  A 201 (-3.8A)
LMZ  A 201 ( 3.8A)
LMZ  A 201 (-4.3A)
 0.59A 1kyvB-1c41A:
26.7
1kyvC-1c41A:
27.1		 1kyvB-1c41A:
47.50
1kyvC-1c41A:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		8 / 12 TRP A  25
GLY A  58
SER A  59
TRP A  60
GLU A  61
LEU A 120
HIS A 127
ILE A 131
 LMZ  A 201 (-3.5A)
LMZ  A 201 (-2.9A)
LMZ  A 201 (-2.5A)
None
LMZ  A 201 (-2.6A)
LMZ  A 201 (-3.8A)
LMZ  A 201 ( 3.8A)
LMZ  A 201 (-4.3A)
 0.60A 1kyvC-1c41A:
27.1
1kyvD-1c41A:
26.7		 1kyvC-1c41A:
47.50
1kyvD-1c41A:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		8 / 12 TRP A  25
GLY A  58
SER A  59
TRP A  60
GLU A  61
LEU A 120
HIS A 127
ILE A 131
 LMZ  A 201 (-3.5A)
LMZ  A 201 (-2.9A)
LMZ  A 201 (-2.5A)
None
LMZ  A 201 (-2.6A)
LMZ  A 201 (-3.8A)
LMZ  A 201 ( 3.8A)
LMZ  A 201 (-4.3A)
 0.59A 1kyvD-1c41A:
26.7
1kyvE-1c41A:
27.6		 1kyvD-1c41A:
47.50
1kyvE-1c41A:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		6 / 11 GLY A  58
SER A  59
TRP A  60
GLU A  61
LEU A 120
HIS A 127
 LMZ  A 201 (-2.9A)
LMZ  A 201 (-2.5A)
None
LMZ  A 201 (-2.6A)
LMZ  A 201 (-3.8A)
LMZ  A 201 ( 3.8A)
 0.49A 2a58A-1c41A:
26.5
2a58E-1c41A:
26.5		 2a58A-1c41A:
47.00
2a58E-1c41A:
47.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		6 / 12 GLY A  58
SER A  59
TRP A  60
GLU A  61
LEU A 120
HIS A 127
 LMZ  A 201 (-2.9A)
LMZ  A 201 (-2.5A)
None
LMZ  A 201 (-2.6A)
LMZ  A 201 (-3.8A)
LMZ  A 201 ( 3.8A)
 0.48A 2a58A-1c41A:
26.5
2a58B-1c41A:
26.4		 2a58A-1c41A:
47.00
2a58B-1c41A:
47.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		6 / 12 GLY A  58
SER A  59
TRP A  60
GLU A  61
LEU A 120
HIS A 127
 LMZ  A 201 (-2.9A)
LMZ  A 201 (-2.5A)
None
LMZ  A 201 (-2.6A)
LMZ  A 201 (-3.8A)
LMZ  A 201 ( 3.8A)
 0.48A 2a58B-1c41A:
26.4
2a58C-1c41A:
26.5		 2a58B-1c41A:
47.00
2a58C-1c41A:
47.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		6 / 11 GLY A  58
SER A  59
TRP A  60
GLU A  61
LEU A 120
HIS A 127
 LMZ  A 201 (-2.9A)
LMZ  A 201 (-2.5A)
None
LMZ  A 201 (-2.6A)
LMZ  A 201 (-3.8A)
LMZ  A 201 ( 3.8A)
 0.49A 2a58C-1c41A:
26.5
2a58D-1c41A:
26.5		 2a58C-1c41A:
47.00
2a58D-1c41A:
47.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		6 / 12 GLY A  58
SER A  59
TRP A  60
GLU A  61
LEU A 120
HIS A 127
 LMZ  A 201 (-2.9A)
LMZ  A 201 (-2.5A)
None
LMZ  A 201 (-2.6A)
LMZ  A 201 (-3.8A)
LMZ  A 201 ( 3.8A)
 0.49A 2a58D-1c41A:
26.5
2a58E-1c41A:
26.5		 2a58D-1c41A:
47.00
2a58E-1c41A:
47.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		4 / 5 LEU A  33
GLY A  36
ILE A  20
ILE A 117
 None
 0.86A 2q9rA-1c41A:
undetectable		 2q9rA-1c41A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		4 / 6 LEU A 114
ILE A  64
ALA A  72
LEU A  75
 None
 0.88A 3kk6B-1c41A:
undetectable		 3kk6B-1c41A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		5 / 10 GLY A  36
ASP A 179
GLY A 168
VAL A 169
VAL A 119
 None
 1.05A 3oxwA-1c41A:
undetectable		 3oxwA-1c41A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		4 / 8 ALA A 132
VAL A 135
LEU A 139
LEU A 155
 None
 0.70A 3roxA-1c41A:
2.4		 3roxA-1c41A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		4 / 7 GLY A 181
ASP A 179
GLY A 177
HIS A 174
 None
 0.83A 4c5nA-1c41A:
3.7		 4c5nA-1c41A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		4 / 8 GLY A 181
ASP A 179
GLY A 177
HIS A 174
 None
 0.78A 4c5nC-1c41A:
3.7		 4c5nC-1c41A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		3 / 5 GLY A 168
GLY A 172
GLU A 171
 None
 0.49A 4z2eA-1c41A:
0.0
4z2eD-1c41A:
2.1		 4z2eA-1c41A:
18.22
4z2eD-1c41A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		5 / 12 VAL A 119
LEU A 155
ALA A 167
ILE A  51
ILE A 117
 None
 1.17A 5hbsA-1c41A:
undetectable		 5hbsA-1c41A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 1c41 LUMAZINE SYNTHASE
(Magnaporthe
grisea) 		5 / 12 MET A 187
LEU A 114
LEU A 139
MET A 140
LEU A 144
 None
 1.13A 5toaB-1c41A:
undetectable		 5toaB-1c41A:
21.71