SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c4k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 10 ALA A 653
GLY A 714
ARG A 220
GLU A 671
PRO A 622
 None
 1.30A 1cmcA-1c4kA:
undetectable
1cmcB-1c4kA:
undetectable		 1cmcA-1c4kA:
13.79
1cmcB-1c4kA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 1k2rA-1c4kA:
0.0
1k2rB-1c4kA:
0.0		 1k2rA-1c4kA:
19.23
1k2rB-1c4kA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.27A 1k2tA-1c4kA:
0.0
1k2tB-1c4kA:
0.0		 1k2tA-1c4kA:
19.23
1k2tB-1c4kA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.29A 1k2tA-1c4kA:
0.0
1k2tB-1c4kA:
0.0		 1k2tA-1c4kA:
19.23
1k2tB-1c4kA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TYR A 489
ASN A 221
TYR A 297
TYR A 484
 None
 1.31A 1kiaA-1c4kA:
1.5		 1kiaA-1c4kA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TYR A 489
ASN A 221
TYR A 297
TYR A 484
 None
 1.31A 1kiaB-1c4kA:
2.8		 1kiaB-1c4kA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TYR A 489
ASN A 221
TYR A 297
TYR A 484
 None
 1.31A 1kiaC-1c4kA:
2.9		 1kiaC-1c4kA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TYR A 489
ASN A 221
TYR A 297
TYR A 484
 None
 1.31A 1kiaD-1c4kA:
2.8		 1kiaD-1c4kA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		3 / 3 ALA A 299
HIS A 300
VAL A 303
 None
 0.36A 1lqtB-1c4kA:
2.1		 1lqtB-1c4kA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		3 / 3 ALA A 299
HIS A 300
VAL A 303
 None
 0.38A 1lquB-1c4kA:
undetectable		 1lquB-1c4kA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.28A 1lzxA-1c4kA:
0.0
1lzxB-1c4kA:
0.0		 1lzxA-1c4kA:
19.23
1lzxB-1c4kA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.29A 1lzxA-1c4kA:
0.0
1lzxB-1c4kA:
0.0		 1lzxA-1c4kA:
19.23
1lzxB-1c4kA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.28A 1lzzA-1c4kA:
0.0
1lzzB-1c4kA:
0.0		 1lzzA-1c4kA:
19.23
1lzzB-1c4kA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 1m00A-1c4kA:
0.0
1m00B-1c4kA:
0.0		 1m00A-1c4kA:
19.23
1m00B-1c4kA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 1mmvA-1c4kA:
0.0
1mmvB-1c4kA:
0.0		 1mmvA-1c4kA:
19.23
1mmvB-1c4kA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 1mmvA-1c4kA:
0.0
1mmvB-1c4kA:
0.0		 1mmvA-1c4kA:
19.23
1mmvB-1c4kA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.26A 1mmwA-1c4kA:
0.0
1mmwB-1c4kA:
0.0		 1mmwA-1c4kA:
19.23
1mmwB-1c4kA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TYR A 489
ASN A 221
TYR A 297
TYR A 484
 None
 1.30A 1nbhA-1c4kA:
1.4		 1nbhA-1c4kA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TYR A 489
ASN A 221
TYR A 297
TYR A 484
 None
 1.31A 1nbhB-1c4kA:
1.3		 1nbhB-1c4kA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TYR A 489
ASN A 221
TYR A 297
TYR A 484
 None
 1.29A 1nbhC-1c4kA:
0.6		 1nbhC-1c4kA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TYR A 489
ASN A 221
TYR A 297
TYR A 484
 None
 1.30A 1nbhD-1c4kA:
0.6		 1nbhD-1c4kA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 1om4A-1c4kA:
0.0
1om4B-1c4kA:
0.0		 1om4A-1c4kA:
19.07
1om4B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 1om4A-1c4kA:
0.0
1om4B-1c4kA:
0.0		 1om4A-1c4kA:
19.07
1om4B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 1om5A-1c4kA:
0.0
1om5B-1c4kA:
0.0		 1om5A-1c4kA:
19.09
1om5B-1c4kA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 1p6hA-1c4kA:
0.0
1p6hB-1c4kA:
0.0		 1p6hA-1c4kA:
19.09
1p6hB-1c4kA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.35A 1p6iA-1c4kA:
0.0
1p6iB-1c4kA:
0.0		 1p6iA-1c4kA:
19.09
1p6iB-1c4kA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.34A 1p6iA-1c4kA:
0.0
1p6iB-1c4kA:
0.0		 1p6iA-1c4kA:
19.09
1p6iB-1c4kA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.26A 1p6jA-1c4kA:
0.0
1p6jB-1c4kA:
0.0		 1p6jA-1c4kA:
19.09
1p6jB-1c4kA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.29A 1p6jA-1c4kA:
0.0
1p6jB-1c4kA:
0.0		 1p6jA-1c4kA:
19.09
1p6jB-1c4kA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 1p6kA-1c4kA:
0.0
1p6kB-1c4kA:
0.0		 1p6kA-1c4kA:
19.23
1p6kB-1c4kA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 SER A 388
PHE A 392
LEU A 284
VAL A 286
VAL A 210
 None
 1.25A 1q23B-1c4kA:
3.2		 1q23B-1c4kA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 SER A 388
PHE A 392
LEU A 284
VAL A 286
VAL A 210
 None
 1.24A 1q23C-1c4kA:
3.5		 1q23C-1c4kA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 11 SER A 388
PHE A 392
LEU A 284
VAL A 286
VAL A 210
 None
 1.28A 1q23F-1c4kA:
3.6		 1q23F-1c4kA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 11 SER A 388
PHE A 392
LEU A 284
VAL A 286
VAL A 210
 None
 1.18A 1q23I-1c4kA:
3.3		 1q23I-1c4kA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 11 SER A 388
PHE A 392
LEU A 284
VAL A 286
VAL A 210
 None
 1.29A 1q23L-1c4kA:
3.3		 1q23L-1c4kA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 4 VAL A 667
ALA A 677
LEU A 645
PHE A 681
 None
 1.12A 1q97B-1c4kA:
0.0		 1q97B-1c4kA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 1rs6A-1c4kA:
0.0
1rs6B-1c4kA:
0.0		 1rs6A-1c4kA:
19.09
1rs6B-1c4kA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 8 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 1rs6A-1c4kA:
0.0
1rs6B-1c4kA:
0.0		 1rs6A-1c4kA:
19.09
1rs6B-1c4kA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.27A 1rs7A-1c4kA:
0.0
1rs7B-1c4kA:
0.0		 1rs7A-1c4kA:
19.09
1rs7B-1c4kA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 1rs7A-1c4kA:
0.0
1rs7B-1c4kA:
0.0		 1rs7A-1c4kA:
19.09
1rs7B-1c4kA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 8 ALA A 712
ILE A 688
GLY A 687
ILE A 683
PRO A 659
 None
 1.31A 1sguA-1c4kA:
undetectable		 1sguA-1c4kA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		3 / 3 GLN A 699
ILE A 698
TYR A 660
 None
 0.72A 1vifA-1c4kA:
0.0		 1vifA-1c4kA:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 1zzqA-1c4kA:
0.0
1zzqB-1c4kA:
0.0		 1zzqA-1c4kA:
19.34
1zzqB-1c4kA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.33A 2g6hA-1c4kA:
0.0
2g6hB-1c4kA:
0.0		 2g6hA-1c4kA:
19.20
2g6hB-1c4kA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 2g6kA-1c4kA:
0.0
2g6kB-1c4kA:
0.0		 2g6kA-1c4kA:
19.20
2g6kB-1c4kA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 GLY A 485
TYR A 490
ASP A 256
ASP A 260
 None
 0.93A 2g72B-1c4kA:
undetectable		 2g72B-1c4kA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 2hx3A-1c4kA:
0.0
2hx3B-1c4kA:
0.0		 2hx3A-1c4kA:
19.07
2hx3B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.29A 2hx3A-1c4kA:
0.0
2hx3B-1c4kA:
0.0		 2hx3A-1c4kA:
19.07
2hx3B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.28A 2hx4A-1c4kA:
0.0
2hx4B-1c4kA:
0.0		 2hx4A-1c4kA:
19.07
2hx4B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 2hx4A-1c4kA:
0.0
2hx4B-1c4kA:
0.0		 2hx4A-1c4kA:
19.07
2hx4B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		3 / 3 ALA A 318
GLY A 197
SER A 225
 PLP  A 955 (-3.4A)
PLP  A 955 (-3.4A)
PLP  A 955 ( 3.9A)
 0.59A 2ivuA-1c4kA:
0.0		 2ivuA-1c4kA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 LEU A 217
ILE A 254
ILE A 306
ARG A 305
 None
 0.94A 2q8hA-1c4kA:
0.0		 2q8hA-1c4kA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 5 GLY A 307
PRO A 345
ILE A 347
ILE A 337
 None
 0.85A 2q9rA-1c4kA:
0.0		 2q9rA-1c4kA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		3 / 3 PRO A 692
GLU A 584
TYR A 587
 None
 0.79A 2zmbA-1c4kA:
undetectable		 2zmbA-1c4kA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.26A 3b3nA-1c4kA:
0.0
3b3nB-1c4kA:
0.0		 3b3nA-1c4kA:
19.07
3b3nB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 3b3nA-1c4kA:
0.0
3b3nB-1c4kA:
0.0		 3b3nA-1c4kA:
19.07
3b3nB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 3b3oA-1c4kA:
0.0
3b3oB-1c4kA:
0.0		 3b3oA-1c4kA:
19.07
3b3oB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 8 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.28A 3b3pA-1c4kA:
undetectable
3b3pB-1c4kA:
0.0		 3b3pA-1c4kA:
19.07
3b3pB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 8 TYR A 102
GLU A 103
SER A   2
VAL A  36
 None
 1.26A 3b9lA-1c4kA:
0.0		 3b9lA-1c4kA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.25A 3dqrA-1c4kA:
0.0
3dqrB-1c4kA:
0.0		 3dqrA-1c4kA:
19.20
3dqrB-1c4kA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.26A 3dqrA-1c4kA:
0.0
3dqrB-1c4kA:
0.0		 3dqrA-1c4kA:
19.20
3dqrB-1c4kA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 3fc5A-1c4kA:
0.0
3fc5B-1c4kA:
0.0		 3fc5A-1c4kA:
19.07
3fc5B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 3fc5A-1c4kA:
0.0
3fc5B-1c4kA:
0.0		 3fc5A-1c4kA:
19.07
3fc5B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		3 / 3 ILE A 251
PHE A 616
HIS A 223
 None
None
PLP  A 955 (-3.4A)
 0.68A 3h0aA-1c4kA:
0.0		 3h0aA-1c4kA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.26A 3hsnA-1c4kA:
0.0
3hsnB-1c4kA:
0.0		 3hsnA-1c4kA:
19.07
3hsnB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 3hsnA-1c4kA:
0.0
3hsnB-1c4kA:
0.0		 3hsnA-1c4kA:
19.07
3hsnB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 3hsoA-1c4kA:
0.0
3hsoB-1c4kA:
0.0		 3hsoA-1c4kA:
19.07
3hsoB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.25A 3hsoA-1c4kA:
0.0
3hsoB-1c4kA:
0.0		 3hsoA-1c4kA:
19.07
3hsoB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 3hspA-1c4kA:
0.0
3hspB-1c4kA:
0.0		 3hspA-1c4kA:
19.07
3hspB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 4 ASP A 708
GLY A 707
LYS A 709
GLU A 706
 None
 1.48A 3hznD-1c4kA:
0.0		 3hznD-1c4kA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 3jt3A-1c4kA:
0.0
3jt3B-1c4kA:
0.0		 3jt3A-1c4kA:
19.07
3jt3B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 3jt5A-1c4kA:
0.0
3jt5B-1c4kA:
0.0		 3jt5A-1c4kA:
19.07
3jt5B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.33A 3jt5A-1c4kA:
0.0
3jt5B-1c4kA:
0.0		 3jt5A-1c4kA:
19.07
3jt5B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 3jt6A-1c4kA:
0.0
3jt6B-1c4kA:
0.0		 3jt6A-1c4kA:
19.07
3jt6B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 3jt7A-1c4kA:
0.0
3jt7B-1c4kA:
0.0		 3jt7A-1c4kA:
19.07
3jt7B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 3jt7A-1c4kA:
0.0
3jt7B-1c4kA:
0.0		 3jt7A-1c4kA:
19.07
3jt7B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 3jt8A-1c4kA:
0.0
3jt8B-1c4kA:
0.0		 3jt8A-1c4kA:
19.07
3jt8B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.27A 3jt8A-1c4kA:
0.0
3jt8B-1c4kA:
0.0		 3jt8A-1c4kA:
19.07
3jt8B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.27A 3jt9A-1c4kA:
0.0
3jt9B-1c4kA:
0.0		 3jt9A-1c4kA:
19.07
3jt9B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 3jt9A-1c4kA:
0.0
3jt9B-1c4kA:
0.0		 3jt9A-1c4kA:
19.07
3jt9B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 3jtaA-1c4kA:
0.0
3jtaB-1c4kA:
0.0		 3jtaA-1c4kA:
19.07
3jtaB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 3jtaA-1c4kA:
0.0
3jtaB-1c4kA:
0.0		 3jtaA-1c4kA:
19.07
3jtaB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 3jwsA-1c4kA:
0.0
3jwsB-1c4kA:
0.0		 3jwsA-1c4kA:
19.07
3jwsB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 3jwsA-1c4kA:
0.0
3jwsB-1c4kA:
0.0		 3jwsA-1c4kA:
19.07
3jwsB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 3jwtA-1c4kA:
0.0
3jwtB-1c4kA:
0.0		 3jwtA-1c4kA:
19.07
3jwtB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 3jwtA-1c4kA:
0.0
3jwtB-1c4kA:
0.0		 3jwtA-1c4kA:
19.07
3jwtB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 3jwuA-1c4kA:
0.0
3jwuB-1c4kA:
0.0		 3jwuA-1c4kA:
19.07
3jwuB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 3jwuA-1c4kA:
0.0
3jwuB-1c4kA:
0.0		 3jwuA-1c4kA:
19.07
3jwuB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 3jwvA-1c4kA:
0.0
3jwvB-1c4kA:
0.0		 3jwvA-1c4kA:
19.07
3jwvB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 3jx4A-1c4kA:
0.0
3jx4B-1c4kA:
0.0		 3jx4A-1c4kA:
19.20
3jx4B-1c4kA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.24A 3jx6A-1c4kA:
0.0
3jx6B-1c4kA:
0.0		 3jx6A-1c4kA:
19.20
3jx6B-1c4kA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 3n2rA-1c4kA:
0.0
3n2rB-1c4kA:
0.0		 3n2rA-1c4kA:
19.07
3n2rB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 3n2rA-1c4kA:
0.0
3n2rB-1c4kA:
0.0		 3n2rA-1c4kA:
19.07
3n2rB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.27A 3n5vA-1c4kA:
0.0
3n5vB-1c4kA:
0.0		 3n5vA-1c4kA:
19.07
3n5vB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.28A 3n5vA-1c4kA:
0.0
3n5vB-1c4kA:
0.0		 3n5vA-1c4kA:
19.07
3n5vB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 3n5zA-1c4kA:
0.0
3n5zB-1c4kA:
0.0		 3n5zA-1c4kA:
19.07
3n5zB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.26A 3nljA-1c4kA:
0.0
3nljB-1c4kA:
0.0		 3nljA-1c4kA:
19.20
3nljB-1c4kA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.27A 3nljA-1c4kA:
0.0
3nljB-1c4kA:
0.0		 3nljA-1c4kA:
19.20
3nljB-1c4kA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.26A 3nlkA-1c4kA:
0.0
3nlkB-1c4kA:
0.0		 3nlkA-1c4kA:
19.07
3nlkB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 3nlkA-1c4kA:
0.0
3nlkB-1c4kA:
undetectable		 3nlkA-1c4kA:
19.07
3nlkB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 3nlnA-1c4kA:
0.0
3nlnB-1c4kA:
0.0		 3nlnA-1c4kA:
19.07
3nlnB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 3nlnA-1c4kA:
0.0
3nlnB-1c4kA:
0.0		 3nlnA-1c4kA:
19.07
3nlnB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.27A 3nloA-1c4kA:
0.0
3nloB-1c4kA:
0.0		 3nloA-1c4kA:
19.07
3nloB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 3nlvA-1c4kA:
0.0
3nlvB-1c4kA:
0.0		 3nlvA-1c4kA:
19.07
3nlvB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.33A 3nlwA-1c4kA:
0.0
3nlwB-1c4kA:
0.0		 3nlwA-1c4kA:
19.07
3nlwB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 3nlyA-1c4kA:
0.0
3nlyB-1c4kA:
0.0		 3nlyA-1c4kA:
19.07
3nlyB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.28A 3nnyA-1c4kA:
0.0
3nnyB-1c4kA:
0.0		 3nnyA-1c4kA:
19.07
3nnyB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 3nnyA-1c4kA:
0.0
3nnyB-1c4kA:
0.0		 3nnyA-1c4kA:
19.07
3nnyB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 3nnzA-1c4kA:
0.0
3nnzB-1c4kA:
0.0		 3nnzA-1c4kA:
19.07
3nnzB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 5 ASN A 202
ASP A 219
THR A 295
SER A 225
 PLP  A 955 (-4.6A)
None
None
PLP  A 955 ( 3.9A)
 1.01A 3p2kC-1c4kA:
undetectable		 3p2kC-1c4kA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.33A 3pngA-1c4kA:
0.0
3pngB-1c4kA:
0.0		 3pngA-1c4kA:
19.07
3pngB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 8 TYR A 603
LEU A 595
CYH A 596
PHE A 691
 None
 1.28A 3po7A-1c4kA:
0.0		 3po7A-1c4kA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 3q99A-1c4kA:
0.0
3q99B-1c4kA:
undetectable		 3q99A-1c4kA:
19.07
3q99B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.29A 3q99A-1c4kA:
0.0
3q99B-1c4kA:
0.0		 3q99A-1c4kA:
19.07
3q99B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 3q9aA-1c4kA:
0.0
3q9aB-1c4kA:
0.0		 3q9aA-1c4kA:
19.07
3q9aB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.35A 3q9aA-1c4kA:
0.0
3q9aB-1c4kA:
0.0		 3q9aA-1c4kA:
19.07
3q9aB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 8 ALA A 517
VAL A 520
LEU A 524
LEU A 540
 None
 0.56A 3roxA-1c4kA:
3.3		 3roxA-1c4kA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.28A 3rqkA-1c4kA:
0.0
3rqkB-1c4kA:
0.0		 3rqkA-1c4kA:
19.07
3rqkB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.33A 3rqkA-1c4kA:
0.0
3rqkB-1c4kA:
0.0		 3rqkA-1c4kA:
19.07
3rqkB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 3rqlA-1c4kA:
0.0
3rqlB-1c4kA:
0.0		 3rqlA-1c4kA:
19.07
3rqlB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 8 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 3rqlA-1c4kA:
0.0
3rqlB-1c4kA:
undetectable		 3rqlA-1c4kA:
19.07
3rqlB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 3rqnA-1c4kA:
0.0
3rqnB-1c4kA:
0.0		 3rqnA-1c4kA:
19.07
3rqnB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 5 SER A 534
PRO A 516
TYR A 603
VAL A 515
 None
 1.31A 3sufC-1c4kA:
undetectable		 3sufC-1c4kA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.25A 3svpA-1c4kA:
0.0
3svpB-1c4kA:
0.0		 3svpA-1c4kA:
19.07
3svpB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 3svpA-1c4kA:
0.0
3svpB-1c4kA:
0.0		 3svpA-1c4kA:
19.07
3svpB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.25A 3svqA-1c4kA:
0.0
3svqB-1c4kA:
0.0		 3svqA-1c4kA:
19.07
3svqB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.28A 3svqA-1c4kA:
0.0
3svqB-1c4kA:
0.0		 3svqA-1c4kA:
19.07
3svqB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 3tylA-1c4kA:
0.0
3tylB-1c4kA:
0.0		 3tylA-1c4kA:
19.07
3tylB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 3tymA-1c4kA:
0.0
3tymB-1c4kA:
0.0		 3tymA-1c4kA:
19.07
3tymB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 3tymA-1c4kA:
0.0
3tymB-1c4kA:
0.0		 3tymA-1c4kA:
19.07
3tymB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 3tynA-1c4kA:
0.0
3tynB-1c4kA:
0.0		 3tynA-1c4kA:
19.07
3tynB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.29A 3tynA-1c4kA:
0.0
3tynB-1c4kA:
0.0		 3tynA-1c4kA:
19.07
3tynB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 3tyoA-1c4kA:
undetectable
3tyoB-1c4kA:
0.0		 3tyoA-1c4kA:
19.07
3tyoB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 SER A 388
PHE A 392
LEU A 284
VAL A 286
VAL A 210
 None
 1.29A 3u9fB-1c4kA:
3.3
3u9fC-1c4kA:
3.1		 3u9fB-1c4kA:
13.95
3u9fC-1c4kA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 10 SER A 388
PHE A 392
LEU A 284
VAL A 286
VAL A 210
 None
 1.30A 3u9fK-1c4kA:
0.0		 3u9fK-1c4kA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 10 SER A 388
PHE A 392
LEU A 284
VAL A 286
VAL A 210
 None
 1.25A 3u9fR-1c4kA:
3.4		 3u9fR-1c4kA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.19A 3ufoA-1c4kA:
0.0
3ufoB-1c4kA:
0.0		 3ufoA-1c4kA:
19.07
3ufoB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 3ufoA-1c4kA:
0.0
3ufoB-1c4kA:
undetectable		 3ufoA-1c4kA:
19.07
3ufoB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.25A 3ufpA-1c4kA:
0.0
3ufpB-1c4kA:
0.0		 3ufpA-1c4kA:
19.07
3ufpB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.24A 3ufpA-1c4kA:
0.0
3ufpB-1c4kA:
0.0		 3ufpA-1c4kA:
19.07
3ufpB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 3ufqA-1c4kA:
0.0
3ufqB-1c4kA:
0.0		 3ufqA-1c4kA:
19.07
3ufqB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.26A 3ufqA-1c4kA:
0.0
3ufqB-1c4kA:
undetectable		 3ufqA-1c4kA:
19.07
3ufqB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.25A 3ufrA-1c4kA:
0.0
3ufrB-1c4kA:
0.0		 3ufrA-1c4kA:
19.07
3ufrB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.26A 3ufrA-1c4kA:
0.0
3ufrB-1c4kA:
0.0		 3ufrA-1c4kA:
19.07
3ufrB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 3uftA-1c4kA:
0.0
3uftB-1c4kA:
0.0		 3uftA-1c4kA:
19.07
3uftB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.29A 3uftA-1c4kA:
0.0
3uftB-1c4kA:
0.0		 3uftA-1c4kA:
19.07
3uftB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 3ufuA-1c4kA:
0.0
3ufuB-1c4kA:
0.0		 3ufuA-1c4kA:
19.07
3ufuB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 3ufvA-1c4kA:
undetectable
3ufvB-1c4kA:
0.0		 3ufvA-1c4kA:
19.07
3ufvB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 3ufwA-1c4kA:
0.0
3ufwB-1c4kA:
0.0		 3ufwA-1c4kA:
19.07
3ufwB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 3ufwA-1c4kA:
0.0
3ufwB-1c4kA:
0.0		 3ufwA-1c4kA:
19.07
3ufwB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 11 TYR A 603
LEU A 595
CYH A 596
ILE A 579
PHE A 691
 None
 1.48A 4a7aA-1c4kA:
undetectable		 4a7aA-1c4kA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 664
ARG A 245
ILE A 251
GLU A 671
 None
 1.11A 4a97H-1c4kA:
0.0		 4a97H-1c4kA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 8 VAL A 664
ARG A 245
ILE A 251
GLU A 671
 None
 1.08A 4a97I-1c4kA:
undetectable		 4a97I-1c4kA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 HIS A 354
SER A 352
GLU A 314
ASP A 219
 PLP  A 955 (-4.1A)
PLP  A 955 (-2.8A)
None
None
 1.28A 4blvA-1c4kA:
3.8		 4blvA-1c4kA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 4c39A-1c4kA:
0.0
4c39B-1c4kA:
0.0		 4c39A-1c4kA:
19.07
4c39B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 4camA-1c4kA:
0.0
4camB-1c4kA:
0.0		 4camA-1c4kA:
19.07
4camB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 4camA-1c4kA:
0.0
4camB-1c4kA:
0.0		 4camA-1c4kA:
19.07
4camB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 4canA-1c4kA:
0.0
4canB-1c4kA:
0.0		 4canA-1c4kA:
19.07
4canB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 4canA-1c4kA:
0.0
4canB-1c4kA:
0.0		 4canA-1c4kA:
19.07
4canB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.28A 4caoA-1c4kA:
0.0
4caoB-1c4kA:
0.0		 4caoA-1c4kA:
19.07
4caoB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.25A 4caoA-1c4kA:
0.0
4caoB-1c4kA:
0.0		 4caoA-1c4kA:
19.07
4caoB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 4capA-1c4kA:
0.0
4capB-1c4kA:
0.0		 4capA-1c4kA:
19.07
4capB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 4caqA-1c4kA:
0.0
4caqB-1c4kA:
0.0		 4caqA-1c4kA:
19.07
4caqB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 4cdtA-1c4kA:
0.0
4cdtB-1c4kA:
0.0		 4cdtA-1c4kA:
19.07
4cdtB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.29A 4cdtA-1c4kA:
0.0
4cdtB-1c4kA:
0.0		 4cdtA-1c4kA:
19.07
4cdtB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 4ctpA-1c4kA:
0.0
4ctpB-1c4kA:
0.0		 4ctpA-1c4kA:
19.07
4ctpB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 4ctrA-1c4kA:
undetectable
4ctrB-1c4kA:
0.0		 4ctrA-1c4kA:
19.07
4ctrB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.26A 4ctrA-1c4kA:
undetectable
4ctrB-1c4kA:
0.0		 4ctrA-1c4kA:
19.07
4ctrB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 4ctuA-1c4kA:
0.0
4ctuB-1c4kA:
0.0		 4ctuA-1c4kA:
19.07
4ctuB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 4ctuA-1c4kA:
0.0
4ctuB-1c4kA:
0.0		 4ctuA-1c4kA:
19.07
4ctuB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 4ctvA-1c4kA:
0.0
4ctvB-1c4kA:
0.0		 4ctvA-1c4kA:
19.07
4ctvB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 4ctwA-1c4kA:
0.0
4ctwB-1c4kA:
0.0		 4ctwA-1c4kA:
19.07
4ctwB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.33A 4ctxA-1c4kA:
0.0
4ctxB-1c4kA:
0.0		 4ctxA-1c4kA:
19.07
4ctxB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 4ctxA-1c4kA:
0.0
4ctxB-1c4kA:
0.0		 4ctxA-1c4kA:
19.07
4ctxB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.33A 4cx5A-1c4kA:
0.0
4cx5B-1c4kA:
0.0		 4cx5A-1c4kA:
19.07
4cx5B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 4d1nA-1c4kA:
0.0
4d1nB-1c4kA:
0.0		 4d1nA-1c4kA:
19.07
4d1nB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 4d1nA-1c4kA:
0.0
4d1nB-1c4kA:
0.0		 4d1nA-1c4kA:
19.07
4d1nB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 4d1nC-1c4kA:
0.0
4d1nD-1c4kA:
0.0		 4d1nC-1c4kA:
19.07
4d1nD-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 4d2yA-1c4kA:
0.0
4d2yB-1c4kA:
0.0		 4d2yA-1c4kA:
19.07
4d2yB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 4d2yA-1c4kA:
0.0
4d2yB-1c4kA:
0.0		 4d2yA-1c4kA:
19.07
4d2yB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 4d2zA-1c4kA:
0.0
4d2zB-1c4kA:
0.0		 4d2zA-1c4kA:
19.07
4d2zB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 4d2zA-1c4kA:
0.0
4d2zB-1c4kA:
0.0		 4d2zA-1c4kA:
19.07
4d2zB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.34A 4d30A-1c4kA:
0.0
4d30B-1c4kA:
0.0		 4d30A-1c4kA:
19.07
4d30B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 4d30A-1c4kA:
undetectable
4d30B-1c4kA:
0.0		 4d30A-1c4kA:
19.07
4d30B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.28A 4d31A-1c4kA:
0.0
4d31B-1c4kA:
0.0		 4d31A-1c4kA:
19.07
4d31B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 4d32A-1c4kA:
undetectable
4d32B-1c4kA:
0.0		 4d32A-1c4kA:
19.07
4d32B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 8 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 4d32A-1c4kA:
0.0
4d32B-1c4kA:
0.0		 4d32A-1c4kA:
19.07
4d32B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 4d3bA-1c4kA:
0.0
4d3bB-1c4kA:
0.0		 4d3bA-1c4kA:
19.07
4d3bB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.33A 4d7oA-1c4kA:
0.0
4d7oB-1c4kA:
0.0		 4d7oA-1c4kA:
19.07
4d7oB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 4d7oA-1c4kA:
0.0
4d7oB-1c4kA:
0.0		 4d7oA-1c4kA:
19.07
4d7oB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 4euxA-1c4kA:
0.0
4euxB-1c4kA:
0.0		 4euxA-1c4kA:
19.07
4euxB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.33A 4euxA-1c4kA:
0.0
4euxB-1c4kA:
0.0		 4euxA-1c4kA:
19.07
4euxB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 4fvwA-1c4kA:
0.0
4fvwB-1c4kA:
0.0		 4fvwA-1c4kA:
19.07
4fvwB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 4fvyA-1c4kA:
0.0
4fvyB-1c4kA:
0.0		 4fvyA-1c4kA:
19.07
4fvyB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 4fw0A-1c4kA:
0.0
4fw0B-1c4kA:
0.0		 4fw0A-1c4kA:
19.07
4fw0B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.33A 4fw0A-1c4kA:
0.0
4fw0B-1c4kA:
0.0		 4fw0A-1c4kA:
19.07
4fw0B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 4gqeA-1c4kA:
0.0
4gqeB-1c4kA:
0.0		 4gqeA-1c4kA:
19.07
4gqeB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 4gqeA-1c4kA:
0.0
4gqeB-1c4kA:
0.0		 4gqeA-1c4kA:
19.07
4gqeB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 4imtA-1c4kA:
0.0
4imtB-1c4kA:
0.0		 4imtA-1c4kA:
19.07
4imtB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.25A 4imwA-1c4kA:
0.0
4imwB-1c4kA:
0.0		 4imwA-1c4kA:
19.07
4imwB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.21A 4imwA-1c4kA:
0.0
4imwB-1c4kA:
0.0		 4imwA-1c4kA:
19.07
4imwB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 4jsgA-1c4kA:
0.0
4jsgB-1c4kA:
0.0		 4jsgA-1c4kA:
19.07
4jsgB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.27A 4jshA-1c4kA:
0.0
4jshB-1c4kA:
0.0		 4jshA-1c4kA:
19.07
4jshB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.28A 4jsiA-1c4kA:
0.0
4jsiB-1c4kA:
0.0		 4jsiA-1c4kA:
19.07
4jsiB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.34A 4jsjA-1c4kA:
0.0
4jsjB-1c4kA:
0.0		 4jsjA-1c4kA:
19.07
4jsjB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 8 ASN A 222
ARG A 220
ASP A 258
LEU A 241
ILE A 306
 None
 1.02A 4k0bA-1c4kA:
0.0		 4k0bA-1c4kA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 5 GLU A 671
ARG A 220
PRO A 622
SER A 674
 None
 1.48A 4k17B-1c4kA:
0.1		 4k17B-1c4kA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 4k5dA-1c4kA:
0.0
4k5dB-1c4kA:
0.0		 4k5dA-1c4kA:
19.07
4k5dB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 4k5eA-1c4kA:
0.0
4k5eB-1c4kA:
0.0		 4k5eA-1c4kA:
19.07
4k5eB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.34A 4k5eA-1c4kA:
0.0
4k5eB-1c4kA:
0.0		 4k5eA-1c4kA:
19.07
4k5eB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 4k5fA-1c4kA:
0.0
4k5fB-1c4kA:
0.0		 4k5fA-1c4kA:
19.07
4k5fB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.28A 4kchA-1c4kA:
0.0
4kchB-1c4kA:
0.0		 4kchA-1c4kA:
19.07
4kchB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.28A 4kchA-1c4kA:
0.0
4kchB-1c4kA:
0.0		 4kchA-1c4kA:
19.07
4kchB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.27A 4kciA-1c4kA:
0.0
4kciB-1c4kA:
0.0		 4kciA-1c4kA:
19.07
4kciB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.28A 4kciA-1c4kA:
0.0
4kciB-1c4kA:
0.0		 4kciA-1c4kA:
19.07
4kciB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 4kcjA-1c4kA:
0.0
4kcjB-1c4kA:
0.0		 4kcjA-1c4kA:
19.07
4kcjB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 4kcjA-1c4kA:
0.0
4kcjB-1c4kA:
0.0		 4kcjA-1c4kA:
19.07
4kcjB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 4kckA-1c4kA:
0.0
4kckB-1c4kA:
0.0		 4kckA-1c4kA:
19.07
4kckB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.23A 4kckA-1c4kA:
0.0
4kckB-1c4kA:
0.0		 4kckA-1c4kA:
19.07
4kckB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.28A 4kclA-1c4kA:
0.0
4kclB-1c4kA:
0.0		 4kclA-1c4kA:
19.07
4kclB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 4kclA-1c4kA:
0.0
4kclB-1c4kA:
0.0		 4kclA-1c4kA:
19.07
4kclB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.28A 4kcmA-1c4kA:
0.0
4kcmB-1c4kA:
0.0		 4kcmA-1c4kA:
19.07
4kcmB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.29A 4kcmA-1c4kA:
0.0
4kcmB-1c4kA:
0.0		 4kcmA-1c4kA:
19.07
4kcmB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 4kcoA-1c4kA:
0.0
4kcoB-1c4kA:
0.0		 4kcoA-1c4kA:
19.07
4kcoB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 4kcoA-1c4kA:
0.0
4kcoB-1c4kA:
0.0		 4kcoA-1c4kA:
19.07
4kcoB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 8 ASN A 222
ARG A 220
ASP A 258
LEU A 241
ILE A 306
 None
 1.10A 4l7iA-1c4kA:
0.0		 4l7iA-1c4kA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 4luxA-1c4kA:
0.0
4luxB-1c4kA:
0.0		 4luxA-1c4kA:
19.07
4luxB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8J_A_ADNA401_1
(RNA 3'-TERMINAL
PHOSPHATE CYCLASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 LEU A 658
GLN A 699
PRO A 661
ASP A 535
HIS A 223
 None
None
None
None
PLP  A 955 (-3.4A)
 1.49A 4o8jA-1c4kA:
0.9		 4o8jA-1c4kA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8J_B_ADNB401_1
(RNA 3'-TERMINAL
PHOSPHATE CYCLASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 LEU A 658
GLN A 699
PRO A 661
ASP A 535
HIS A 223
 None
None
None
None
PLP  A 955 (-3.4A)
 1.47A 4o8jB-1c4kA:
0.3		 4o8jB-1c4kA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 PHE A 111
PRO A 108
ALA A 416
GLY A 417
LEU A 420
 None
 1.13A 4oadA-1c4kA:
undetectable		 4oadA-1c4kA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 PRO A 108
ALA A 409
ALA A 416
GLY A 417
LEU A 420
 None
 1.04A 4oaeA-1c4kA:
undetectable		 4oaeA-1c4kA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 11 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.16A 4qvnH-1c4kA:
undetectable
4qvnI-1c4kA:
undetectable		 4qvnH-1c4kA:
17.71
4qvnI-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 10 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.15A 4qvnV-1c4kA:
0.0
4qvnW-1c4kA:
0.0		 4qvnV-1c4kA:
17.71
4qvnW-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.17A 4qvpH-1c4kA:
undetectable
4qvpI-1c4kA:
undetectable		 4qvpH-1c4kA:
17.71
4qvpI-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.16A 4qvpV-1c4kA:
undetectable
4qvpW-1c4kA:
undetectable		 4qvpV-1c4kA:
17.71
4qvpW-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 11 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.17A 4qvqH-1c4kA:
undetectable
4qvqI-1c4kA:
undetectable		 4qvqH-1c4kA:
17.71
4qvqI-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 11 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.17A 4qvqV-1c4kA:
undetectable
4qvqW-1c4kA:
undetectable		 4qvqV-1c4kA:
17.71
4qvqW-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.17A 4qvyV-1c4kA:
undetectable
4qvyW-1c4kA:
undetectable		 4qvyV-1c4kA:
17.71
4qvyW-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 11 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.17A 4qw0H-1c4kA:
undetectable
4qw0I-1c4kA:
undetectable		 4qw0H-1c4kA:
17.71
4qw0I-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 11 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.16A 4qw0V-1c4kA:
undetectable
4qw0W-1c4kA:
undetectable		 4qw0V-1c4kA:
17.71
4qw0W-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.14A 4qw1H-1c4kA:
undetectable
4qw1I-1c4kA:
undetectable		 4qw1H-1c4kA:
17.71
4qw1I-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.13A 4qw1V-1c4kA:
undetectable
4qw1W-1c4kA:
undetectable		 4qw1V-1c4kA:
17.71
4qw1W-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 11 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.16A 4qwuH-1c4kA:
undetectable
4qwuI-1c4kA:
undetectable		 4qwuH-1c4kA:
17.71
4qwuI-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 11 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.15A 4qwuV-1c4kA:
undetectable
4qwuW-1c4kA:
0.0		 4qwuV-1c4kA:
17.71
4qwuW-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.29A 4uh0A-1c4kA:
0.0
4uh0B-1c4kA:
0.0		 4uh0A-1c4kA:
19.07
4uh0B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.27A 4uh1A-1c4kA:
0.0
4uh1B-1c4kA:
0.0		 4uh1A-1c4kA:
19.07
4uh1B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 4uh1A-1c4kA:
0.0
4uh1B-1c4kA:
0.0		 4uh1A-1c4kA:
19.07
4uh1B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.35A 4uh3A-1c4kA:
0.0
4uh3B-1c4kA:
0.0		 4uh3A-1c4kA:
19.07
4uh3B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 4uh4A-1c4kA:
0.0
4uh4B-1c4kA:
0.0		 4uh4A-1c4kA:
19.07
4uh4B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 4uh5A-1c4kA:
0.0
4uh5B-1c4kA:
0.0		 4uh5A-1c4kA:
19.39
4uh5B-1c4kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 4uh6A-1c4kA:
0.0
4uh6B-1c4kA:
0.0		 4uh6A-1c4kA:
19.39
4uh6B-1c4kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 4upmA-1c4kA:
0.0
4upmB-1c4kA:
0.0		 4upmA-1c4kA:
19.07
4upmB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 4upnA-1c4kA:
0.0
4upnB-1c4kA:
0.0		 4upnA-1c4kA:
19.07
4upnB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.26A 4upnA-1c4kA:
0.0
4upnB-1c4kA:
0.0		 4upnA-1c4kA:
19.07
4upnB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 4upoA-1c4kA:
0.0
4upoB-1c4kA:
0.0		 4upoA-1c4kA:
19.07
4upoB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 4upoA-1c4kA:
0.0
4upoB-1c4kA:
0.0		 4upoA-1c4kA:
19.07
4upoB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 4uppA-1c4kA:
0.0
4uppB-1c4kA:
0.0		 4uppA-1c4kA:
19.07
4uppB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 4uppA-1c4kA:
0.0
4uppB-1c4kA:
0.0		 4uppA-1c4kA:
19.07
4uppB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.35A 4v3uA-1c4kA:
0.0
4v3uB-1c4kA:
0.0		 4v3uA-1c4kA:
19.07
4v3uB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.27A 4v3vA-1c4kA:
0.0
4v3vB-1c4kA:
0.0		 4v3vA-1c4kA:
19.07
4v3vB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.29A 4v3vA-1c4kA:
0.0
4v3vB-1c4kA:
0.0		 4v3vA-1c4kA:
19.07
4v3vB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 4v3wA-1c4kA:
0.0
4v3wB-1c4kA:
0.0		 4v3wA-1c4kA:
19.07
4v3wB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 4v3wA-1c4kA:
undetectable
4v3wB-1c4kA:
0.0		 4v3wA-1c4kA:
19.07
4v3wB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.33A 4v3xA-1c4kA:
0.0
4v3xB-1c4kA:
0.0		 4v3xA-1c4kA:
19.07
4v3xB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 4v3xA-1c4kA:
0.0
4v3xB-1c4kA:
0.0		 4v3xA-1c4kA:
19.07
4v3xB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 8 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.29A 4v3yA-1c4kA:
undetectable
4v3yB-1c4kA:
undetectable		 4v3yA-1c4kA:
19.07
4v3yB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.33A 4v3zA-1c4kA:
0.0
4v3zB-1c4kA:
0.0		 4v3zA-1c4kA:
19.07
4v3zB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.33A 4v3zA-1c4kA:
0.0
4v3zB-1c4kA:
0.0		 4v3zA-1c4kA:
19.07
4v3zB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		3 / 3 SER A 198
GLU A 532
GLU A 547
 PLP  A 955 (-3.9A)
None
None
 0.77A 4ymgB-1c4kA:
undetectable		 4ymgB-1c4kA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.26A 5ad6A-1c4kA:
0.0
5ad6B-1c4kA:
0.0		 5ad6A-1c4kA:
19.07
5ad6B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.28A 5ad6A-1c4kA:
undetectable
5ad6B-1c4kA:
0.0		 5ad6A-1c4kA:
19.07
5ad6B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.28A 5ad7A-1c4kA:
0.0
5ad7B-1c4kA:
0.0		 5ad7A-1c4kA:
19.07
5ad7B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.26A 5ad9A-1c4kA:
undetectable
5ad9B-1c4kA:
0.0		 5ad9A-1c4kA:
19.07
5ad9B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.22A 5ad9A-1c4kA:
0.0
5ad9B-1c4kA:
0.0		 5ad9A-1c4kA:
19.07
5ad9B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.35A 5agkA-1c4kA:
0.0
5agkB-1c4kA:
0.0		 5agkA-1c4kA:
19.07
5agkB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 5aglA-1c4kA:
undetectable
5aglB-1c4kA:
0.0		 5aglA-1c4kA:
19.07
5aglB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 5agmA-1c4kA:
0.0
5agmB-1c4kA:
0.0		 5agmA-1c4kA:
19.07
5agmB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.33A 5agmA-1c4kA:
0.0
5agmB-1c4kA:
0.0		 5agmA-1c4kA:
19.07
5agmB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 5agnA-1c4kA:
0.0
5agnB-1c4kA:
0.0		 5agnA-1c4kA:
19.07
5agnB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.34A 5agpA-1c4kA:
0.0
5agpB-1c4kA:
0.0		 5agpA-1c4kA:
19.07
5agpB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 11 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.09A 5bxnH-1c4kA:
undetectable
5bxnI-1c4kA:
undetectable		 5bxnH-1c4kA:
17.43
5bxnI-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.16A 5cz7V-1c4kA:
undetectable
5cz7W-1c4kA:
undetectable		 5cz7V-1c4kA:
17.71
5cz7W-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.30A 5fvpA-1c4kA:
0.0
5fvpB-1c4kA:
0.0		 5fvpA-1c4kA:
19.07
5fvpB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.33A 5fvqA-1c4kA:
0.0
5fvqB-1c4kA:
0.0		 5fvqA-1c4kA:
19.07
5fvqB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 5fvsA-1c4kA:
0.0
5fvsB-1c4kA:
0.0		 5fvsA-1c4kA:
19.07
5fvsB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 5fvtA-1c4kA:
0.0
5fvtB-1c4kA:
0.0		 5fvtA-1c4kA:
19.07
5fvtB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.28A 5fvuA-1c4kA:
0.0
5fvuB-1c4kA:
0.0		 5fvuA-1c4kA:
19.39
5fvuB-1c4kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 5fvvA-1c4kA:
0.0
5fvvB-1c4kA:
0.0		 5fvvA-1c4kA:
19.39
5fvvB-1c4kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.34A 5fvwA-1c4kA:
0.0
5fvwB-1c4kA:
0.0		 5fvwA-1c4kA:
19.39
5fvwB-1c4kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 5fw0A-1c4kA:
0.0
5fw0B-1c4kA:
0.0		 5fw0A-1c4kA:
19.07
5fw0B-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 ILE A  56
VAL A  26
VAL A  36
SER A  28
 None
 0.94A 5jwaH-1c4kA:
undetectable		 5jwaH-1c4kA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		3 / 3 LYS A 495
LEU A 555
ILE A 539
 None
 0.74A 5kc0A-1c4kA:
undetectable		 5kc0A-1c4kA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 SER A 364
THR A 363
GLN A 362
ALA A 201
THR A 204
 None
 1.32A 5l5zH-1c4kA:
undetectable
5l5zI-1c4kA:
0.0		 5l5zH-1c4kA:
17.71
5l5zI-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.23A 5l5zH-1c4kA:
undetectable
5l5zI-1c4kA:
0.0		 5l5zH-1c4kA:
17.71
5l5zI-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 SER A 364
THR A 363
GLN A 362
ALA A 201
THR A 204
 None
 1.34A 5l5zV-1c4kA:
0.0
5l5zW-1c4kA:
0.0		 5l5zV-1c4kA:
17.71
5l5zW-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.20A 5l5zV-1c4kA:
0.0
5l5zW-1c4kA:
0.0		 5l5zV-1c4kA:
17.71
5l5zW-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.25A 5l66H-1c4kA:
undetectable
5l66I-1c4kA:
undetectable		 5l66H-1c4kA:
17.71
5l66I-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 THR A 243
GLN A 612
GLY A 252
THR A 291
ASP A 535
 None
 1.24A 5l66V-1c4kA:
undetectable
5l66W-1c4kA:
undetectable		 5l66V-1c4kA:
17.71
5l66W-1c4kA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 ASP A 157
ASP A 147
ARG A 137
GLN A 134
 None
 1.14A 5l6eA-1c4kA:
undetectable		 5l6eA-1c4kA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 5unwA-1c4kA:
0.0
5unwB-1c4kA:
0.0		 5unwA-1c4kA:
19.07
5unwB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.28A 5unxA-1c4kA:
0.0
5unxB-1c4kA:
0.0		 5unxA-1c4kA:
19.07
5unxB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 5unyA-1c4kA:
0.0
5unyB-1c4kA:
0.0		 5unyA-1c4kA:
19.07
5unyB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 5uo2A-1c4kA:
0.0
5uo2B-1c4kA:
0.0		 5uo2A-1c4kA:
19.39
5uo2B-1c4kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 5uo3A-1c4kA:
0.0
5uo3B-1c4kA:
0.0		 5uo3A-1c4kA:
19.39
5uo3B-1c4kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.27A 5uo5A-1c4kA:
0.0
5uo5B-1c4kA:
0.0		 5uo5A-1c4kA:
19.39
5uo5B-1c4kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 5uo6A-1c4kA:
0.0
5uo6B-1c4kA:
0.0		 5uo6A-1c4kA:
19.39
5uo6B-1c4kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 5uo7A-1c4kA:
0.0
5uo7B-1c4kA:
0.0		 5uo7A-1c4kA:
19.39
5uo7B-1c4kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.29A 5vuiA-1c4kA:
0.0
5vuiB-1c4kA:
0.0		 5vuiA-1c4kA:
19.07
5vuiB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.29A 5vuiA-1c4kA:
0.0
5vuiB-1c4kA:
0.0		 5vuiA-1c4kA:
19.07
5vuiB-1c4kA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 5vv3A-1c4kA:
0.0
5vv3B-1c4kA:
0.0		 5vv3A-1c4kA:
19.39
5vv3B-1c4kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 5vv4A-1c4kA:
0.0
5vv4B-1c4kA:
0.0		 5vv4A-1c4kA:
19.39
5vv4B-1c4kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.28A 5vv5A-1c4kA:
0.0
5vv5B-1c4kA:
0.0		 5vv5A-1c4kA:
19.39
5vv5B-1c4kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 5vv5A-1c4kA:
0.0
5vv5B-1c4kA:
0.0		 5vv5A-1c4kA:
19.39
5vv5B-1c4kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 TYR A 702
GLU A 706
TYR A 713
GLY A 714
 None
 0.88A 5x7pB-1c4kA:
0.9		 5x7pB-1c4kA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 10 LEU A 645
ILE A 688
PHE A 703
LEU A 658
ALA A 657
 None
 1.16A 5y7pB-1c4kA:
0.0		 5y7pB-1c4kA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 10 LEU A 645
ILE A 688
PHE A 703
LEU A 658
ALA A 657
 None
 1.09A 5y7pD-1c4kA:
0.0		 5y7pD-1c4kA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 10 LEU A 645
ILE A 688
PHE A 703
LEU A 658
ALA A 657
 None
 1.11A 5y7pH-1c4kA:
undetectable		 5y7pH-1c4kA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.27A 6auqA-1c4kA:
0.0
6auqB-1c4kA:
0.0		 6auqA-1c4kA:
7.39
6auqB-1c4kA:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 6autA-1c4kA:
0.0
6autB-1c4kA:
0.0		 6autA-1c4kA:
7.39
6autB-1c4kA:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.33A 6auvA-1c4kA:
0.0
6auvB-1c4kA:
0.0		 6auvA-1c4kA:
7.39
6auvB-1c4kA:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.33A 6auyA-1c4kA:
0.0
6auyB-1c4kA:
0.0		 6auyA-1c4kA:
7.30
6auyB-1c4kA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.31A 6auzA-1c4kA:
0.0
6auzB-1c4kA:
0.0		 6auzA-1c4kA:
7.30
6auzB-1c4kA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.29A 6av0A-1c4kA:
0.0
6av0B-1c4kA:
0.0		 6av0A-1c4kA:
7.30
6av0B-1c4kA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.32A 6av1A-1c4kA:
0.0
6av1B-1c4kA:
0.0		 6av1A-1c4kA:
7.30
6av1B-1c4kA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.36A 6av2A-1c4kA:
0.0
6av2B-1c4kA:
0.0		 6av2A-1c4kA:
7.30
6av2B-1c4kA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.29A 6av2A-1c4kA:
0.0
6av2B-1c4kA:
0.0		 6av2A-1c4kA:
7.30
6av2B-1c4kA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 VAL A 667
TRP A 673
PHE A 681
GLU A 649
 None
 1.31A 6av3A-1c4kA:
0.0
6av3B-1c4kA:
0.0		 6av3A-1c4kA:
7.30
6av3B-1c4kA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.34A 6av3A-1c4kA:
0.0
6av3B-1c4kA:
0.0		 6av3A-1c4kA:
7.30
6av3B-1c4kA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.30A 6av4A-1c4kA:
0.0
6av4B-1c4kA:
0.0		 6av4A-1c4kA:
7.30
6av4B-1c4kA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 TRP A 673
PHE A 681
GLU A 649
VAL A 667
 None
 1.32A 6av5A-1c4kA:
0.0
6av5B-1c4kA:
0.0		 6av5A-1c4kA:
7.30
6av5B-1c4kA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 6 PHE A 282
ARG A 283
LEU A 215
ALA A 268
 None
 1.06A 6b89B-1c4kA:
undetectable		 6b89B-1c4kA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBP_B_ADNB404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		5 / 12 ASP A 370
ILE A 347
ILE A 313
HIS A 308
ASP A 344
 None
 1.36A 6fbpA-1c4kA:
undetectable
6fbpB-1c4kA:
undetectable		 6fbpA-1c4kA:
8.35
6fbpB-1c4kA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)
(Lactobacillus
sp.
30A) 		4 / 7 ILE A 251
GLN A 288
HIS A 223
VAL A 664
 None
PLP  A 955 (-4.3A)
PLP  A 955 (-3.4A)
None
 1.17A 6j20A-1c4kA:
0.0		 6j20A-1c4kA:
21.67