SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c4t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 1c4t PROTEIN
(DIHYDROLIPOAMIDE
SUCCINYLTRANSFERASE)
(Escherichia
coli) 		5 / 12 ASP A 396
GLU A 395
MET A 209
PRO A 365
ASP A 352
 None
 1.42A 1s14B-1c4tA:
0.0		 1s14B-1c4tA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 1c4t PROTEIN
(DIHYDROLIPOAMIDE
SUCCINYLTRANSFERASE)
(Escherichia
coli) 		3 / 3 ASP A 314
VAL A 279
PRO A 275
 None
 0.78A 2avvA-1c4tA:
undetectable		 2avvA-1c4tA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1c4t PROTEIN
(DIHYDROLIPOAMIDE
SUCCINYLTRANSFERASE)
(Escherichia
coli) 		5 / 7 VAL A 241
LEU A 245
ALA A 240
LEU A 345
LEU A 369
 None
 1.33A 5jq7A-1c4tA:
0.0		 5jq7A-1c4tA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1c4t PROTEIN
(DIHYDROLIPOAMIDE
SUCCINYLTRANSFERASE)
(Escherichia
coli) 		3 / 3 THR A 323
MET A 347
HIS A 348
 None
 0.98A 5uunA-1c4tA:
0.0		 5uunA-1c4tA:
22.41