SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c7g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 8 ILE A 263
LEU A 294
MET A 299
GLU A 300
ALA A 301
 None
 1.42A 1a29A-1c7gA:
undetectable		 1a29A-1c7gA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 9 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.30A 1c9sA-1c7gA:
undetectable
1c9sB-1c7gA:
undetectable		 1c9sA-1c7gA:
12.25
1c9sB-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.25A 1c9sB-1c7gA:
undetectable
1c9sC-1c7gA:
undetectable		 1c9sB-1c7gA:
12.25
1c9sC-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.27A 1c9sG-1c7gA:
undetectable
1c9sH-1c7gA:
undetectable		 1c9sG-1c7gA:
12.25
1c9sH-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		4 / 4 ILE A  43
MET A  28
VAL A 403
GLY A 375
 None
 1.31A 1e06B-1c7gA:
undetectable		 1e06B-1c7gA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.25A 1gtfC-1c7gA:
undetectable
1gtfD-1c7gA:
undetectable		 1gtfC-1c7gA:
12.25
1gtfD-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 9 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.28A 1gtfF-1c7gA:
undetectable
1gtfG-1c7gA:
undetectable		 1gtfF-1c7gA:
12.25
1gtfG-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.26A 1gtfG-1c7gA:
undetectable
1gtfH-1c7gA:
undetectable		 1gtfG-1c7gA:
12.25
1gtfH-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.26A 1gtfH-1c7gA:
undetectable
1gtfI-1c7gA:
undetectable		 1gtfH-1c7gA:
12.25
1gtfI-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 11 THR A  35
VAL A 403
LEU A 347
ALA A 349
LEU A 427
 None
 1.05A 1jinA-1c7gA:
0.0		 1jinA-1c7gA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		3 / 3 ALA A 415
HIS A 416
VAL A 419
 None
 0.31A 1lqtB-1c7gA:
undetectable		 1lqtB-1c7gA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		3 / 3 ALA A 415
HIS A 416
VAL A 419
 None
 0.30A 1lquB-1c7gA:
undetectable		 1lquB-1c7gA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 8 ALA A 301
ILE A 263
GLY A 264
GLY A 255
ALA A  55
 None
 1.06A 1sguA-1c7gA:
0.0		 1sguA-1c7gA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 11 THR A 125
HIS A 129
THR A 126
ARG A 100
THR A 252
 PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
PLP  A1000 (-3.8A)
None
 1.34A 1utdM-1c7gA:
undetectable
1utdN-1c7gA:
undetectable		 1utdM-1c7gA:
12.25
1utdN-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		3 / 3 GLN A 321
HIS A 317
ARG A 410
 None
 0.95A 1zlqA-1c7gA:
0.0		 1zlqA-1c7gA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 12 LEU A 427
LEU A 366
SER A 378
ARG A  21
ASP A  22
 None
 1.16A 2bm9B-1c7gA:
3.6		 2bm9B-1c7gA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 12 GLU A 286
HIS A  97
LYS A 132
HIS A 129
THR A 125
 None
None
None
None
PLP  A1000 ( 4.5A)
 1.30A 2c6nB-1c7gA:
undetectable		 2c6nB-1c7gA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		4 / 5 GLN A 364
PHE A 453
PHE A 439
GLY A 387
 None
 1.30A 2qmzA-1c7gA:
2.5
2qmzB-1c7gA:
2.9		 2qmzA-1c7gA:
19.22
2qmzB-1c7gA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_K_AG2K671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		4 / 8 ILE A 336
GLN A 190
ARG A 330
GLY A 326
 None
 0.91A 2qqcH-1c7gA:
undetectable
2qqcK-1c7gA:
undetectable		 2qqcH-1c7gA:
12.72
2qqcK-1c7gA:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		4 / 7 GLY A 265
THR A  96
GLN A  98
PHE A 123
 None
None
PLP  A1000 (-3.7A)
PLP  A1000 (-3.7A)
 1.06A 2qx4A-1c7gA:
3.0
2qx4B-1c7gA:
2.6		 2qx4A-1c7gA:
19.22
2qx4B-1c7gA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		4 / 8 LEU A 106
LEU A 267
ALA A 248
PHE A  90
 None
 0.91A 2vcvF-1c7gA:
0.0		 2vcvF-1c7gA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		4 / 8 THR A 402
LEU A 405
ASP A  50
GLU A 338
 None
 1.07A 2zw9A-1c7gA:
2.8		 2zw9A-1c7gA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		4 / 8 GLY A 292
CYH A 251
PHE A 212
GLY A 101
 None
 0.97A 3ko0O-1c7gA:
undetectable
3ko0Q-1c7gA:
0.0		 3ko0O-1c7gA:
12.00
3ko0Q-1c7gA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		4 / 7 GLY A 101
GLY A 292
CYH A 251
PHE A 212
 None
 0.94A 3ko0M-1c7gA:
0.0
3ko0P-1c7gA:
undetectable		 3ko0M-1c7gA:
12.00
3ko0P-1c7gA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		3 / 3 ALA A 118
VAL A 117
GLN A 130
 None
 0.73A 3of4B-1c7gA:
0.0		 3of4B-1c7gA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		4 / 4 GLY A 287
GLY A 292
THR A  96
LEU A 105
 None
 0.94A 3si7C-1c7gA:
0.5
3si7D-1c7gA:
0.5		 3si7C-1c7gA:
20.62
3si7D-1c7gA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 12 VAL A 376
LEU A 366
LEU A 325
VAL A 322
THR A  35
 None
 1.11A 4eckA-1c7gA:
undetectable		 4eckA-1c7gA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		4 / 6 GLN A 364
PHE A 453
PRO A 362
PHE A 439
 None
 1.20A 4fgkA-1c7gA:
2.7		 4fgkA-1c7gA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		4 / 8 GLY A 265
GLY A 293
VAL A 282
GLU A 286
 None
 0.91A 4fgzA-1c7gA:
2.8		 4fgzA-1c7gA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 7 ILE A 263
LEU A 294
GLU A 286
GLY A 265
GLY A 264
 None
 1.24A 5a06A-1c7gA:
undetectable		 5a06A-1c7gA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 7 ILE A 263
LEU A 294
GLU A 286
GLY A 265
GLY A 264
 None
 1.28A 5a06C-1c7gA:
2.8		 5a06C-1c7gA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 7 ILE A 263
LEU A 294
GLU A 286
GLY A 265
GLY A 264
 None
 1.25A 5a06E-1c7gA:
undetectable		 5a06E-1c7gA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 7 ILE A 263
LEU A 294
GLU A 286
GLY A 265
GLY A 264
 None
 1.24A 5a06F-1c7gA:
0.7		 5a06F-1c7gA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.28A 5eeuD-1c7gA:
undetectable
5eeuE-1c7gA:
undetectable		 5eeuD-1c7gA:
12.25
5eeuE-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.26A 5eeuH-1c7gA:
undetectable
5eeuI-1c7gA:
undetectable		 5eeuH-1c7gA:
12.25
5eeuI-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.25A 5eeuJ-1c7gA:
undetectable
5eeuK-1c7gA:
undetectable		 5eeuJ-1c7gA:
12.25
5eeuK-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.28A 5eevD-1c7gA:
undetectable
5eevE-1c7gA:
undetectable		 5eevD-1c7gA:
12.25
5eevE-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.25A 5eevJ-1c7gA:
undetectable
5eevK-1c7gA:
undetectable		 5eevJ-1c7gA:
12.25
5eevK-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.28A 5eewD-1c7gA:
undetectable
5eewE-1c7gA:
undetectable		 5eewD-1c7gA:
12.25
5eewE-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.26A 5eewH-1c7gA:
undetectable
5eewI-1c7gA:
undetectable		 5eewH-1c7gA:
12.25
5eewI-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.25A 5eewJ-1c7gA:
undetectable
5eewK-1c7gA:
undetectable		 5eewJ-1c7gA:
12.25
5eewK-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.28A 5eexD-1c7gA:
undetectable
5eexE-1c7gA:
undetectable		 5eexD-1c7gA:
12.25
5eexE-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.26A 5eexH-1c7gA:
undetectable
5eexI-1c7gA:
undetectable		 5eexH-1c7gA:
12.25
5eexI-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 11 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.28A 5eexI-1c7gA:
undetectable
5eexJ-1c7gA:
undetectable		 5eexI-1c7gA:
12.25
5eexJ-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.25A 5eexJ-1c7gA:
0.0
5eexK-1c7gA:
undetectable		 5eexJ-1c7gA:
12.25
5eexK-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.28A 5eeyD-1c7gA:
undetectable
5eeyE-1c7gA:
undetectable		 5eeyD-1c7gA:
12.25
5eeyE-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 11 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.28A 5eeyI-1c7gA:
undetectable
5eeyJ-1c7gA:
undetectable		 5eeyI-1c7gA:
12.25
5eeyJ-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.26A 5eeyJ-1c7gA:
undetectable
5eeyK-1c7gA:
undetectable		 5eeyJ-1c7gA:
12.25
5eeyK-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.29A 5eezD-1c7gA:
undetectable
5eezE-1c7gA:
undetectable		 5eezD-1c7gA:
12.25
5eezE-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 11 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.28A 5eezI-1c7gA:
undetectable
5eezJ-1c7gA:
undetectable		 5eezI-1c7gA:
12.25
5eezJ-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.29A 5ef0D-1c7gA:
undetectable
5ef0E-1c7gA:
undetectable		 5ef0D-1c7gA:
12.25
5ef0E-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 11 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.28A 5ef0I-1c7gA:
undetectable
5ef0J-1c7gA:
undetectable		 5ef0I-1c7gA:
12.25
5ef0J-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.29A 5ef1D-1c7gA:
undetectable
5ef1E-1c7gA:
undetectable		 5ef1D-1c7gA:
12.25
5ef1E-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 11 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.28A 5ef1I-1c7gA:
undetectable
5ef1J-1c7gA:
undetectable		 5ef1I-1c7gA:
12.25
5ef1J-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.29A 5ef2D-1c7gA:
undetectable
5ef2E-1c7gA:
undetectable		 5ef2D-1c7gA:
12.25
5ef2E-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 11 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.28A 5ef2I-1c7gA:
undetectable
5ef2J-1c7gA:
undetectable		 5ef2I-1c7gA:
12.25
5ef2J-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 10 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.29A 5ef3D-1c7gA:
undetectable
5ef3E-1c7gA:
undetectable		 5ef3D-1c7gA:
12.25
5ef3E-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 11 ARG A 100
THR A 252
THR A 125
HIS A 129
THR A 126
 PLP  A1000 (-3.8A)
None
PLP  A1000 ( 4.5A)
None
PLP  A1000 ( 4.8A)
 1.28A 5ef3I-1c7gA:
undetectable
5ef3J-1c7gA:
undetectable		 5ef3I-1c7gA:
12.25
5ef3J-1c7gA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		3 / 3 ASN A 151
ASP A 327
GLY A 326
 None
 0.62A 5fctB-1c7gA:
0.0		 5fctB-1c7gA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		4 / 6 PHE A  77
LEU A 294
SER A  74
GLY A 296
 None
 1.14A 5o4yF-1c7gA:
undetectable		 5o4yF-1c7gA:
2.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 1c7g TYROSINE
PHENOL-LYASE
(Pantoea
agglomerans) 		5 / 12 THR A 406
ILE A 407
ALA A 309
ASP A 258
LEU A 260
 None
 1.08A 6ie8A-1c7gA:
0.4		 6ie8A-1c7gA:
20.13