SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c7j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 8 GLY A 106
GLU A 188
SER A 189
PHE A 314
HIS A 399
 None
 0.86A 1ax9A-1c7jA:
44.3		 1ax9A-1c7jA:
32.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_2
(PROTEIN (HIV-1
PROTEASE))		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 8 LEU A 166
GLY A 178
ILE A 130
PHE A 208
 None
 0.71A 1d4sB-1c7jA:
undetectable		 1d4sB-1c7jA:
16.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 ASP A  66
GLY A 105
GLY A 106
SER A 189
HIS A 399
 None
 0.88A 1dx6A-1c7jA:
45.4		 1dx6A-1c7jA:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 GLY A 105
GLY A 106
SER A 189
PHE A 314
HIS A 399
 None
 0.62A 1dx6A-1c7jA:
45.4		 1dx6A-1c7jA:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 GLY A 105
GLY A 106
TYR A 109
SER A 189
HIS A 399
 None
 0.56A 1dx6A-1c7jA:
45.4		 1dx6A-1c7jA:
32.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 8 ALA A 330
LEU A 361
LEU A 362
ARG A 219
 None
 0.90A 1ereE-1c7jA:
undetectable		 1ereE-1c7jA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 8 ALA A 330
LEU A 361
LEU A 362
ARG A 219
 None
 0.91A 1ereF-1c7jA:
undetectable		 1ereF-1c7jA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 THR A 326
ALA A 330
LEU A 331
LEU A 362
ARG A 219
 SO4  A 490 (-3.3A)
None
None
None
None
 1.24A 1errA-1c7jA:
undetectable		 1errA-1c7jA:
19.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 ASP A  66
GLY A 106
GLU A 188
SER A 189
HIS A 399
 None
 0.85A 1maaA-1c7jA:
43.3		 1maaA-1c7jA:
34.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 GLY A 106
TYR A 118
SER A 189
PHE A 314
HIS A 399
 None
 0.61A 1maaC-1c7jA:
44.6		 1maaC-1c7jA:
34.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 8 GLY A 106
GLU A 188
SER A 189
HIS A 399
 None
 0.28A 1maaD-1c7jA:
43.3		 1maaD-1c7jA:
34.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 LEU A  67
GLY A 106
SER A 189
PHE A 363
HIS A 399
 None
 0.80A 1mx1D-1c7jA:
44.1		 1mx1D-1c7jA:
36.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		7 / 12 ASP A  66
GLY A 105
GLY A 106
GLU A 188
SER A 189
PHE A 314
HIS A 399
 None
 1.32A 1qtiA-1c7jA:
44.3		 1qtiA-1c7jA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		6 / 12 GLY A 105
GLY A 106
GLU A 188
SER A 189
PHE A 314
HIS A 399
 None
 0.69A 1qtiA-1c7jA:
44.3		 1qtiA-1c7jA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		6 / 12 GLY A 105
GLY A 106
TYR A 109
GLU A 188
SER A 189
HIS A 399
 None
 0.58A 1qtiA-1c7jA:
44.3		 1qtiA-1c7jA:
32.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 8 ALA A 211
GLY A 216
GLY A 192
PRO A 288
ALA A 200
 None
 1.27A 1sguA-1c7jA:
0.0		 1sguA-1c7jA:
16.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		6 / 12 ASP A  66
GLY A 105
GLY A 106
SER A 189
PHE A 314
HIS A 399
 None
 1.36A 1w6rA-1c7jA:
45.4		 1w6rA-1c7jA:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 GLY A 105
GLY A 106
SER A 189
PHE A 314
HIS A 399
 None
 0.67A 1w6rA-1c7jA:
45.4		 1w6rA-1c7jA:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 GLY A 105
GLY A 106
TYR A 109
SER A 189
HIS A 399
 None
 0.56A 1w6rA-1c7jA:
45.4		 1w6rA-1c7jA:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 11 ASP A  66
GLY A 106
GLU A 188
SER A 189
HIS A 399
 None
 1.01A 1w76A-1c7jA:
44.3		 1w76A-1c7jA:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 11 GLY A 106
GLU A 188
SER A 189
PHE A 314
HIS A 399
 None
 0.69A 1w76A-1c7jA:
44.3		 1w76A-1c7jA:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 11 GLY A 106
TYR A 109
GLU A 188
SER A 189
HIS A 399
 None
 0.65A 1w76A-1c7jA:
44.3		 1w76A-1c7jA:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 11 GLY A 106
TYR A 109
GLU A 188
SER A 189
HIS A 399
 None
 1.38A 1w76A-1c7jA:
44.3		 1w76A-1c7jA:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		6 / 10 ASP A  66
GLY A 105
GLY A 106
GLU A 188
SER A 189
HIS A 399
 None
 0.93A 1w76B-1c7jA:
44.1		 1w76B-1c7jA:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		6 / 10 GLY A 105
GLY A 106
GLU A 188
SER A 189
PHE A 314
HIS A 399
 None
 0.63A 1w76B-1c7jA:
44.1		 1w76B-1c7jA:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		6 / 10 GLY A 105
GLY A 106
TYR A 109
GLU A 188
SER A 189
HIS A 399
 None
 0.57A 1w76B-1c7jA:
44.1		 1w76B-1c7jA:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 8 GLY A 105
GLY A 106
SER A 189
ALA A 190
HIS A 399
 None
 0.22A 1yajC-1c7jA:
43.3		 1yajC-1c7jA:
36.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		7 / 8 GLY A 191
GLY A 105
GLY A 106
SER A 189
ALA A 190
LEU A  67
HIS A 399
 None
 1.09A 1yajC-1c7jA:
43.3		 1yajC-1c7jA:
36.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 6 GLY A 105
SER A 189
LEU A  67
HIS A 399
 None
 0.96A 1yajF-1c7jA:
43.0		 1yajF-1c7jA:
36.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 9 GLY A 105
GLY A 106
SER A 189
ALA A 190
HIS A 399
 None
 0.85A 2aceA-1c7jA:
45.4		 2aceA-1c7jA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 7 GLY A 106
GLU A 188
SER A 189
PHE A 314
HIS A 399
 None
 0.87A 2ackA-1c7jA:
45.8		 2ackA-1c7jA:
32.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 7 TYR A  57
GLY A 113
THR A 133
ASN A 135
 None
 0.95A 2g70A-1c7jA:
1.7		 2g70A-1c7jA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 7 TYR A  57
GLY A 113
THR A 133
ASN A 135
 None
 0.89A 2g70B-1c7jA:
undetectable		 2g70B-1c7jA:
21.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 8 TYR A 118
GLU A 188
PHE A 314
HIS A 399
 None
 0.66A 2ha4A-1c7jA:
44.5		 2ha4A-1c7jA:
34.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		6 / 12 THR A 326
ALA A 330
LEU A 331
LEU A 361
LEU A 362
ARG A 219
 SO4  A 490 (-3.3A)
None
None
None
None
None
 1.37A 2qxsB-1c7jA:
undetectable		 2qxsB-1c7jA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 8 PHE A 208
ALA A 297
LEU A 302
ALA A 211
 None
 0.86A 2vcvF-1c7jA:
0.0		 2vcvF-1c7jA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 8 ALA A  54
ASP A  53
THR A   8
ILE A  27
 None
 0.66A 3el0A-1c7jA:
undetectable		 3el0A-1c7jA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 PRO A 475
THR A 462
SER A 446
ILE A 432
LEU A 465
 None
 1.27A 3iv6A-1c7jA:
2.4		 3iv6A-1c7jA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		3 / 3 ARG A 308
ASP A 360
ASP A 309
 None
 0.82A 3jb3A-1c7jA:
0.0		 3jb3A-1c7jA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 7 GLU A 115
TYR A 109
TYR A 136
TYR A 118
 None
 1.38A 3ku9B-1c7jA:
undetectable		 3ku9B-1c7jA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		3 / 3 SER A 148
ASP A 155
ASN A 156
 None
 0.96A 3lslA-1c7jA:
0.0
3lslD-1c7jA:
0.0		 3lslA-1c7jA:
21.46
3lslD-1c7jA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 11 GLU A 289
ALA A 217
ILE A 195
ALA A 211
GLN A 374
 None
 1.24A 3nmuB-1c7jA:
0.0
3nmuJ-1c7jA:
undetectable		 3nmuB-1c7jA:
22.44
3nmuJ-1c7jA:
18.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 7 GLY A 106
SER A 189
PHE A 363
HIS A 399
 None
 0.58A 3o9mA-1c7jA:
45.8		 3o9mA-1c7jA:
33.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 8 ALA A 297
ILE A 292
ALA A 211
MET A 213
 None
 0.71A 3r9tA-1c7jA:
undetectable		 3r9tA-1c7jA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 TYR A 136
LEU A 198
GLY A 187
GLY A 192
ALA A 211
 None
 1.16A 4a6dA-1c7jA:
0.0		 4a6dA-1c7jA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 6 ALA A  41
ALA A 203
PRO A 202
THR A 283
 None
 0.97A 4dtzA-1c7jA:
0.0		 4dtzA-1c7jA:
23.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 GLY A 105
GLY A 106
SER A 189
PHE A 314
HIS A 399
 None
 0.59A 4ey6A-1c7jA:
45.2		 4ey6A-1c7jA:
34.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 GLY A 105
GLY A 106
SER A 189
PHE A 314
HIS A 399
 None
 0.88A 4ey6A-1c7jA:
45.2		 4ey6A-1c7jA:
34.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 GLY A 105
GLY A 106
TYR A 109
SER A 189
HIS A 399
 None
 0.48A 4ey6A-1c7jA:
45.2		 4ey6A-1c7jA:
34.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		6 / 12 GLY A 105
GLY A 106
GLU A 188
SER A 189
PHE A 314
HIS A 399
 None
 0.57A 4ey6B-1c7jA:
43.8		 4ey6B-1c7jA:
34.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		6 / 12 GLY A 105
GLY A 106
GLU A 188
SER A 189
PHE A 314
HIS A 399
 None
 0.86A 4ey6B-1c7jA:
43.8		 4ey6B-1c7jA:
34.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		6 / 12 GLY A 105
GLY A 106
TYR A 109
GLU A 188
SER A 189
HIS A 399
 None
 0.49A 4ey6B-1c7jA:
43.8		 4ey6B-1c7jA:
34.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_A_TESA503_1
(CYTOCHROME P450
MONOOXYGENASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 PHE A 274
PHE A 275
ALA A 258
ALA A 259
LEU A 146
 None
 1.08A 4j6dA-1c7jA:
0.0		 4j6dA-1c7jA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_B_TESB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 PHE A 274
PHE A 275
ALA A 258
ALA A 259
LEU A 146
 None
 1.07A 4j6dB-1c7jA:
0.0		 4j6dB-1c7jA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 PHE A 274
PHE A 275
ALA A 258
ALA A 259
LEU A 146
 None
 1.09A 4jbtA-1c7jA:
0.0		 4jbtA-1c7jA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		3 / 3 LEU A 279
LYS A 223
THR A 222
 None
 0.63A 4lj0A-1c7jA:
0.0		 4lj0A-1c7jA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		3 / 3 SER A 189
MET A 193
ASP A 360
 None
 0.91A 4mm4B-1c7jA:
undetectable		 4mm4B-1c7jA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 6 TYR A 118
ASN A 409
GLU A 214
LEU A 123
 None
 1.14A 4twdB-1c7jA:
0.0
4twdC-1c7jA:
0.0		 4twdB-1c7jA:
20.00
4twdC-1c7jA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 6 TYR A 118
ASN A 409
GLU A 214
LEU A 123
 None
 1.14A 4twdD-1c7jA:
0.0
4twdE-1c7jA:
0.0		 4twdD-1c7jA:
20.00
4twdE-1c7jA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 6 TYR A 118
ASN A 409
GLU A 214
LEU A 123
 None
 1.19A 4twdI-1c7jA:
0.0
4twdJ-1c7jA:
0.0		 4twdI-1c7jA:
20.00
4twdJ-1c7jA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 LEU A 166
ILE A 300
ILE A 195
GLY A 191
LEU A 134
 None
 1.02A 4y8wC-1c7jA:
0.0		 4y8wC-1c7jA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 7 TYR A 136
GLY A 191
SER A 194
LEU A 198
 None
 1.14A 5bphB-1c7jA:
undetectable		 5bphB-1c7jA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 5 SER A 350
GLY A 311
THR A 306
GLU A 310
 None
 1.11A 5btiA-1c7jA:
0.0
5btiB-1c7jA:
undetectable		 5btiA-1c7jA:
22.78
5btiB-1c7jA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 5 SER A 350
GLY A 311
THR A 306
GLU A 310
 None
 1.11A 5btiC-1c7jA:
0.0
5btiD-1c7jA:
2.5		 5btiC-1c7jA:
22.78
5btiD-1c7jA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_A_5D5A930_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 LEU A 410
THR A 307
PHE A 385
HIS A 430
ILE A 437
 None
 1.22A 5dlvA-1c7jA:
undetectable		 5dlvA-1c7jA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		3 / 3 GLY A 127
GLN A 433
LYS A 441
 None
 0.92A 5imsB-1c7jA:
undetectable		 5imsB-1c7jA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		5 / 12 ILE A 212
LEU A 302
GLU A 402
HIS A 399
GLY A 187
 None
 1.19A 5k7uA-1c7jA:
undetectable		 5k7uA-1c7jA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		3 / 3 GLU A 402
TRP A 102
HIS A 399
 None
 0.90A 5xipA-1c7jA:
0.0		 5xipA-1c7jA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_1
(CARNOSINE
N-METHYLTRANSFERASE)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 5 GLN A 276
ARG A 219
TYR A 333
ASP A 260
 None
 1.28A 5yf0A-1c7jA:
2.0		 5yf0A-1c7jA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)
(Bacillus
subtilis) 		4 / 6 LEU A 401
TYR A 118
GLN A 162
GLU A 188
 None
 1.31A 6djzC-1c7jA:
undetectable		 6djzC-1c7jA:
19.50