SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c8m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1c8m HUMAN RHINOVIRUS 16
COAT PROTEIN
(Rhinovirus
A) 		4 / 4 HIS 2 130
ASP 2 169
ASN 2 136
ASP 2 175
 None
 1.45A 1wg8A-1c8m2:
undetectable		 1wg8A-1c8m2:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 1c8m HUMAN RHINOVIRUS 16
COAT PROTEIN
(Rhinovirus
A) 		3 / 3 VAL 2 208
ASN 2 218
TRP 2 219
 None
 1.11A 2y00B-1c8m2:
undetectable		 2y00B-1c8m2:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 1c8m HUMAN RHINOVIRUS 16
COAT PROTEIN
(Rhinovirus
A) 		3 / 3 SER 2  60
GLU 2 250
ASP 2  57
 None
 0.82A 3bwmA-1c8m2:
undetectable		 3bwmA-1c8m2:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_1
(COMT PROTEIN)		 1c8m HUMAN RHINOVIRUS 16
COAT PROTEIN
(Rhinovirus
A) 		3 / 3 SER 2  60
GLU 2 250
ASP 2  57
 None
 0.84A 3bwyA-1c8m2:
undetectable		 3bwyA-1c8m2:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 1c8m HUMAN RHINOVIRUS 16
COAT PROTEIN
(Rhinovirus
A) 		5 / 12 ASN 2  61
SER 2 245
GLY 2  19
LEU 2  66
ASP 2  67
 None
 1.37A 3r24A-1c8m2:
undetectable		 3r24A-1c8m2:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 1c8m HUMAN RHINOVIRUS 16
COAT PROTEIN
(Rhinovirus
A) 		5 / 12 LEU 2  86
MET 2 247
ILE 2  23
ILE 2  16
HIS 2 109
 None
 1.30A 4j24C-1c8m2:
undetectable		 4j24C-1c8m2:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 1c8m HUMAN RHINOVIRUS 16
COAT PROTEIN
(Rhinovirus
A) 		4 / 8 TRP 2  79
SER 2 167
HIS 2 130
ILE 2 224
 None
 1.19A 4ms4A-1c8m2:
undetectable		 4ms4A-1c8m2:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 1c8m HUMAN RHINOVIRUS 16
COAT PROTEIN
(Rhinovirus
A) 		3 / 3 SER 2  60
GLU 2 250
ASP 2  57
 None
 0.84A 4xudA-1c8m2:
undetectable		 4xudA-1c8m2:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 1c8m HUMAN RHINOVIRUS 16
COAT PROTEIN
(Rhinovirus
A) 		4 / 4 VAL 2 110
ALA 2 198
ASN 2 195
GLN 2 188
 None
 1.44A 4zgfA-1c8m2:
0.0		 4zgfA-1c8m2:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 1c8m HUMAN RHINOVIRUS 16
COAT PROTEIN
(Rhinovirus
A) 		4 / 6 ILE 2  16
PHE 2  63
ARG 2  18
ILE 2 201
 None
 1.29A 4zzcA-1c8m2:
0.0
4zzcB-1c8m2:
0.0		 4zzcA-1c8m2:
21.36
4zzcB-1c8m2:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 1c8m HUMAN RHINOVIRUS 16
COAT PROTEIN
(Rhinovirus
A) 		4 / 6 ILE 2  16
PHE 2  63
ARG 2  18
ILE 2 201
 None
 1.35A 4zzcB-1c8m2:
undetectable
4zzcC-1c8m2:
0.0		 4zzcB-1c8m2:
21.36
4zzcC-1c8m2:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 1c8m HUMAN RHINOVIRUS 16
COAT PROTEIN
(Rhinovirus
A) 		4 / 5 ARG 2 103
THR 2  43
ALA 2  47
ASP 2  46
 None
 1.26A 5mfxA-1c8m2:
0.0		 5mfxA-1c8m2:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1c8m HUMAN RHINOVIRUS 16
COAT PROTEIN
(Rhinovirus
A) 		6 / 12 ILE 2 190
LEU 2 221
VAL 2 242
ILE 2 240
LEU 2 183
LEU 2 179
 None
 1.14A 5ycnA-1c8m2:
undetectable		 5ycnA-1c8m2:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1c8m HUMAN RHINOVIRUS 16
COAT PROTEIN
(Rhinovirus
A) 		5 / 12 PHE 2 189
LEU 2 221
ILE 2 240
LEU 2 183
LEU 2 179
 None
 1.10A 5ycpA-1c8m2:
undetectable		 5ycpA-1c8m2:
12.44