SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c8n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 1c8n COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		3 / 3 TRP A 121
GLU A  95
TYR A 262
 None
 1.11A 2a3aA-1c8nA:
undetectable		 2a3aA-1c8nA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1c8n COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 8 GLY A 221
THR A 222
ALA A 223
ALA A 224
 None
 0.43A 2ej3A-1c8nA:
undetectable		 2ej3A-1c8nA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1c8n COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 8 GLY A 221
THR A 222
ALA A 223
ALA A 224
 None
 0.41A 2ej3C-1c8nA:
undetectable		 2ej3C-1c8nA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 1c8n COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 7 ILE A 115
TYR A 217
PHE A 212
ASP A 213
 None
 0.98A 2qebA-1c8nA:
undetectable		 2qebA-1c8nA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 1c8n COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 7 ILE A 115
TYR A 217
PHE A 212
ASP A 213
 None
 0.95A 2qebB-1c8nA:
undetectable		 2qebB-1c8nA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_F_5FWF1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1c8n COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 6 GLU A 268
LYS A 131
LYS A  87
GLU A 265
 None
 1.30A 4a7tF-1c8nA:
0.0		 4a7tF-1c8nA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1c8n COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		3 / 3 VAL A 209
SER A 136
TRP A 134
 None
 0.79A 5jwaA-1c8nA:
undetectable		 5jwaA-1c8nA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1c8n COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		3 / 3 LYS A 261
LEU A 114
ILE A 258
 None
 0.67A 5kc0A-1c8nA:
undetectable		 5kc0A-1c8nA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA609_0
(ACETYLCHOLINESTERASE)		 1c8n COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 6 TYR A 159
TYR A 176
ASP A 163
HIS A 242
 None
 1.39A 5ov9A-1c8nA:
undetectable		 5ov9A-1c8nA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 1c8n COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 7 TYR A 159
TYR A 176
ASP A 163
HIS A 242
 None
 1.41A 5ov9B-1c8nA:
undetectable		 5ov9B-1c8nA:
18.64