SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c9k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)		 1c9k ADENOSYLCOBINAMIDE
KINASE
(Salmonella
enterica) 		4 / 4 ILE A  67
ASP A 166
LEU A 161
ARG A 124
 None
 1.47A 2a7qA-1c9kA:
0.7		 2a7qA-1c9kA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 1c9k ADENOSYLCOBINAMIDE
KINASE
(Salmonella
enterica) 		5 / 12 LEU A  89
ASN A  88
LEU A  90
VAL A 157
THR A  31
 None
None
None
None
5GP  A 604 (-4.6A)
 1.33A 2q7kA-1c9kA:
undetectable		 2q7kA-1c9kA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 1c9k ADENOSYLCOBINAMIDE
KINASE
(Salmonella
enterica) 		5 / 12 LEU A  89
ASN A  88
LEU A  90
VAL A 157
THR A  31
 None
None
None
None
5GP  A 604 (-4.6A)
 1.32A 2q7lA-1c9kA:
undetectable		 2q7lA-1c9kA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 1c9k ADENOSYLCOBINAMIDE
KINASE
(Salmonella
enterica) 		5 / 12 LEU A  89
ASN A  88
LEU A  90
VAL A 157
THR A  31
 None
None
None
None
5GP  A 604 (-4.6A)
 1.39A 2yloA-1c9kA:
undetectable		 2yloA-1c9kA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 1c9k ADENOSYLCOBINAMIDE
KINASE
(Salmonella
enterica) 		4 / 8 LEU A 118
ILE A  82
ARG A 160
GLY A 155
 None
 0.78A 3b9lA-1c9kA:
1.4		 3b9lA-1c9kA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 1c9k ADENOSYLCOBINAMIDE
KINASE
(Salmonella
enterica) 		4 / 4 ILE A  29
ARG A 124
ILE A  77
THR A  31
 None
None
None
5GP  A 604 (-4.6A)
 1.30A 3ia4C-1c9kA:
2.3		 3ia4C-1c9kA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1c9k ADENOSYLCOBINAMIDE
KINASE
(Salmonella
enterica) 		5 / 12 LEU A 161
ILE A 115
ILE A 111
ARG A 151
ALA A 154
 None
 1.21A 3uj7A-1c9kA:
0.0		 3uj7A-1c9kA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_1
(HIV-1 PROTEASE)		 1c9k ADENOSYLCOBINAMIDE
KINASE
(Salmonella
enterica) 		4 / 7 ALA A 165
ASP A 166
ILE A  77
THR A   5
 None
 0.62A 4eyrA-1c9kA:
undetectable		 4eyrA-1c9kA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVC_A_BEZA301_0
(DIGUANYLATE CYCLASE
DOSC)		 1c9k ADENOSYLCOBINAMIDE
KINASE
(Salmonella
enterica) 		5 / 8 ILE A  67
LEU A  66
ILE A  77
LEU A  79
LEU A  27
 None
 0.97A 4zvcA-1c9kA:
0.0
4zvcB-1c9kA:
0.0		 4zvcA-1c9kA:
19.78
4zvcB-1c9kA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVC_A_BEZA301_0
(DIGUANYLATE CYCLASE
DOSC)		 1c9k ADENOSYLCOBINAMIDE
KINASE
(Salmonella
enterica) 		5 / 8 ILE A  77
LEU A  79
LEU A  27
ILE A  67
LEU A  66
 None
 0.97A 4zvcA-1c9kA:
0.0
4zvcB-1c9kA:
0.0		 4zvcA-1c9kA:
19.78
4zvcB-1c9kA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 1c9k ADENOSYLCOBINAMIDE
KINASE
(Salmonella
enterica) 		5 / 12 VAL A 136
GLU A 135
LEU A  89
GLN A 116
LEU A 161
 None
 1.34A 5m50E-1c9kA:
3.1		 5m50E-1c9kA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 1c9k ADENOSYLCOBINAMIDE
KINASE
(Salmonella
enterica) 		4 / 7 HIS A  15
LEU A  78
VAL A 130
TRP A 169
 None
 1.26A 6g2pA-1c9kA:
undetectable		 6g2pA-1c9kA:
18.47