SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1c9w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 7 THR A  19
SER A  22
SER A  76
LEU A 104
 None
 1.17A 1ibgL-1c9wA:
0.0		 1ibgL-1c9wA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 8 ILE A  74
LEU A  99
ILE A  58
VAL A  31
ILE A  42
 None
 1.40A 1linA-1c9wA:
undetectable		 1linA-1c9wA:
18.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S2A_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 12 TRP A  79
HIS A 110
GLU A 185
TYR A 209
SER A 210
 None
NAP  A 350 (-4.0A)
None
NAP  A 350 (-3.5A)
NAP  A 350 (-2.4A)
 0.26A 1s2aA-1c9wA:
45.6		 1s2aA-1c9wA:
46.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 8 TYR A  48
CYH A 298
TYR A 209
LEU A 300
 NAP  A 350 (-4.8A)
NAP  A 350 ( 4.1A)
NAP  A 350 (-3.5A)
None
 1.27A 1uw6A-1c9wA:
undetectable
1uw6B-1c9wA:
undetectable		 1uw6A-1c9wA:
20.13
1uw6B-1c9wA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 8 TYR A  48
CYH A 298
TYR A 209
LEU A 300
 NAP  A 350 (-4.8A)
NAP  A 350 ( 4.1A)
NAP  A 350 (-3.5A)
None
 1.28A 1uw6D-1c9wA:
undetectable
1uw6E-1c9wA:
undetectable		 1uw6D-1c9wA:
20.13
1uw6E-1c9wA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 8 TYR A  48
CYH A 298
TYR A 209
LEU A 300
 NAP  A 350 (-4.8A)
NAP  A 350 ( 4.1A)
NAP  A 350 (-3.5A)
None
 1.30A 1uw6G-1c9wA:
undetectable
1uw6H-1c9wA:
undetectable		 1uw6G-1c9wA:
20.13
1uw6H-1c9wA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 8 TYR A  48
CYH A 298
TYR A 209
LEU A 300
 NAP  A 350 (-4.8A)
NAP  A 350 ( 4.1A)
NAP  A 350 (-3.5A)
None
 1.24A 1uw6P-1c9wA:
undetectable
1uw6Q-1c9wA:
undetectable		 1uw6P-1c9wA:
20.13
1uw6Q-1c9wA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 8 LEU A 300
TYR A  48
CYH A 298
TYR A 209
 None
NAP  A 350 (-4.8A)
NAP  A 350 ( 4.1A)
NAP  A 350 (-3.5A)
 1.36A 1uw6P-1c9wA:
undetectable
1uw6T-1c9wA:
undetectable		 1uw6P-1c9wA:
20.13
1uw6T-1c9wA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 6 ARG A 255
GLN A 192
GLU A 193
ILE A 196
 None
 1.05A 2fcnA-1c9wA:
undetectable
2fcnB-1c9wA:
undetectable		 2fcnA-1c9wA:
17.81
2fcnB-1c9wA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 12 GLU A  51
LEU A 108
ASP A 105
VAL A 153
ALA A 155
 None
 1.25A 2kceA-1c9wA:
0.0		 2kceA-1c9wA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		3 / 3 PHE A 161
PHE A 137
PHE A  83
 None
 0.84A 2od9A-1c9wA:
undetectable		 2od9A-1c9wA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		3 / 3 PHE A 161
PHE A 137
PHE A  83
 None
 0.84A 2qqgA-1c9wA:
undetectable		 2qqgA-1c9wA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 8 GLY A  55
ILE A  42
VAL A  31
VAL A  27
 None
 0.73A 3fi0B-1c9wA:
undetectable		 3fi0B-1c9wA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 8 GLY A  55
ILE A  42
VAL A  31
VAL A  27
 None
 0.78A 3fi0G-1c9wA:
undetectable		 3fi0G-1c9wA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 8 GLY A  55
ILE A  42
VAL A  31
VAL A  27
 None
 0.80A 3fi0I-1c9wA:
undetectable		 3fi0I-1c9wA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 8 GLY A  55
ILE A  42
VAL A  31
VAL A  27
 None
 0.74A 3fi0Q-1c9wA:
undetectable		 3fi0Q-1c9wA:
23.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R43_A_ID8A332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 12 TYR A  48
TRP A  79
HIS A 110
ASN A 160
TYR A 209
 NAP  A 350 (-4.8A)
None
NAP  A 350 (-4.0A)
NAP  A 350 (-3.2A)
NAP  A 350 (-3.5A)
 0.22A 3r43A-1c9wA:
45.3		 3r43A-1c9wA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R58_A_NPSA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		6 / 10 TYR A  48
HIS A 110
ASN A 160
TYR A 209
PRO A 310
TYR A 311
 NAP  A 350 (-4.8A)
NAP  A 350 (-4.0A)
NAP  A 350 (-3.2A)
NAP  A 350 (-3.5A)
None
None
 0.68A 3r58A-1c9wA:
44.3		 3r58A-1c9wA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R6I_A_JMSA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 12 TYR A  48
TRP A  79
HIS A 110
ASN A 160
TYR A 209
 NAP  A 350 (-4.8A)
None
NAP  A 350 (-4.0A)
NAP  A 350 (-3.2A)
NAP  A 350 (-3.5A)
 0.27A 3r6iA-1c9wA:
44.1		 3r6iA-1c9wA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R8G_A_IZPA409_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 9 TYR A  48
HIS A 110
ASN A 160
TYR A 209
PRO A 310
 NAP  A 350 (-4.8A)
NAP  A 350 (-4.0A)
NAP  A 350 (-3.2A)
NAP  A 350 (-3.5A)
None
 0.39A 3r8gA-1c9wA:
44.1		 3r8gA-1c9wA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R94_A_FLRA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		6 / 12 TYR A  48
HIS A 110
ASN A 160
TYR A 209
PRO A 310
TYR A 311
 NAP  A 350 (-4.8A)
NAP  A 350 (-4.0A)
NAP  A 350 (-3.2A)
NAP  A 350 (-3.5A)
None
None
 0.68A 3r94A-1c9wA:
44.0		 3r94A-1c9wA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RX3_A_SUZA317_1
(ALDOSE REDUCTASE)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 10 TRP A  20
TYR A  48
HIS A 110
PHE A 122
CYH A 298
 NAP  A 350 (-4.4A)
NAP  A 350 (-4.8A)
NAP  A 350 (-4.0A)
None
NAP  A 350 ( 4.1A)
 0.78A 3rx3A-1c9wA:
50.3		 3rx3A-1c9wA:
69.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S3G_A_TLTA317_1
(ALDOSE REDUCTASE)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 7 TRP A  20
TYR A  48
HIS A 110
PHE A 122
 NAP  A 350 (-4.4A)
NAP  A 350 (-4.8A)
NAP  A 350 (-4.0A)
None
 0.54A 3s3gA-1c9wA:
50.3		 3s3gA-1c9wA:
69.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S3G_A_TLTA317_1
(ALDOSE REDUCTASE)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 7 TYR A  48
HIS A 110
PHE A 122
CYH A 298
 NAP  A 350 (-4.8A)
NAP  A 350 (-4.0A)
None
NAP  A 350 ( 4.1A)
 0.73A 3s3gA-1c9wA:
50.3		 3s3gA-1c9wA:
69.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U2C_A_SUZA2001_1
(ALDOSE REDUCTASE)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 9 TRP A  20
TYR A  48
HIS A 110
PHE A 122
CYH A 298
 NAP  A 350 (-4.4A)
NAP  A 350 (-4.8A)
NAP  A 350 (-4.0A)
None
NAP  A 350 ( 4.1A)
 0.82A 3u2cA-1c9wA:
50.5		 3u2cA-1c9wA:
70.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UG8_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		7 / 12 HIS A 110
ASN A 160
TYR A 209
SER A 210
SER A 214
PRO A 310
TYR A 311
 NAP  A 350 (-4.0A)
NAP  A 350 (-3.2A)
NAP  A 350 (-3.5A)
NAP  A 350 (-2.4A)
NAP  A 350 (-2.9A)
None
None
 1.06A 3ug8A-1c9wA:
44.1		 3ug8A-1c9wA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UG8_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		7 / 12 TRP A  79
HIS A 110
ASN A 160
TYR A 209
SER A 210
SER A 214
PRO A 310
 None
NAP  A 350 (-4.0A)
NAP  A 350 (-3.2A)
NAP  A 350 (-3.5A)
NAP  A 350 (-2.4A)
NAP  A 350 (-2.9A)
None
 0.90A 3ug8A-1c9wA:
44.1		 3ug8A-1c9wA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UG8_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		7 / 12 TYR A  48
HIS A 110
ASN A 160
TYR A 209
SER A 210
PRO A 310
TYR A 311
 NAP  A 350 (-4.8A)
NAP  A 350 (-4.0A)
NAP  A 350 (-3.2A)
NAP  A 350 (-3.5A)
NAP  A 350 (-2.4A)
None
None
 0.75A 3ug8A-1c9wA:
44.1		 3ug8A-1c9wA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UG8_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		7 / 12 TYR A  48
TRP A  79
HIS A 110
ASN A 160
TYR A 209
SER A 210
PRO A 310
 NAP  A 350 (-4.8A)
None
NAP  A 350 (-4.0A)
NAP  A 350 (-3.2A)
NAP  A 350 (-3.5A)
NAP  A 350 (-2.4A)
None
 0.51A 3ug8A-1c9wA:
44.1		 3ug8A-1c9wA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UGR_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 12 TRP A  79
HIS A 110
TYR A 209
SER A 210
SER A 214
 None
NAP  A 350 (-4.0A)
NAP  A 350 (-3.5A)
NAP  A 350 (-2.4A)
NAP  A 350 (-2.9A)
 0.82A 3ugrA-1c9wA:
44.2		 3ugrA-1c9wA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 7 ASN A 160
GLN A  21
PRO A 310
TYR A 311
 NAP  A 350 (-3.2A)
None
None
None
 1.22A 3ugrA-1c9wA:
44.2		 3ugrA-1c9wA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 7 TYR A  48
ASN A 160
GLU A 185
PRO A 310
TYR A 311
 NAP  A 350 (-4.8A)
NAP  A 350 (-3.2A)
None
None
None
 0.77A 3ugrA-1c9wA:
44.2		 3ugrA-1c9wA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 8 TRP A  20
TRP A  79
HIS A 110
PHE A 122
PRO A 218
 NAP  A 350 (-4.4A)
None
NAP  A 350 (-4.0A)
None
None
 0.53A 3v35A-1c9wA:
50.4		 3v35A-1c9wA:
69.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_2
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 4 PRO A 123
LEU A 121
HIS A 110
LEU A 108
 None
None
NAP  A 350 (-4.0A)
None
 1.29A 3vw7A-1c9wA:
undetectable		 3vw7A-1c9wA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 4 SER A 159
LEU A 190
TYR A 209
PRO A 112
 NAP  A 350 (-2.9A)
None
NAP  A 350 (-3.5A)
None
 1.31A 4jksB-1c9wA:
1.9		 4jksB-1c9wA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 4 SER A 159
LEU A 190
TYR A 209
PRO A 112
 NAP  A 350 (-2.9A)
None
NAP  A 350 (-3.5A)
None
 1.31A 4kalA-1c9wA:
2.0		 4kalA-1c9wA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 4 SER A 159
LEU A 190
TYR A 209
PRO A 112
 NAP  A 350 (-2.9A)
None
NAP  A 350 (-3.5A)
None
 1.32A 4kalB-1c9wA:
2.0		 4kalB-1c9wA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 4 SER A 159
LEU A 190
TYR A 209
PRO A 112
 NAP  A 350 (-2.9A)
None
NAP  A 350 (-3.5A)
None
 1.31A 4lcaB-1c9wA:
2.0		 4lcaB-1c9wA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 9 THR A   8
LEU A   6
ALA A 155
GLN A 183
THR A 205
 None
None
None
NAP  A 350 (-4.6A)
None
 1.19A 4ltwA-1c9wA:
undetectable		 4ltwA-1c9wA:
19.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVV_A_GBMA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 9 TYR A  48
TRP A  79
HIS A 110
ASN A 160
TYR A 209
 NAP  A 350 (-4.8A)
None
NAP  A 350 (-4.0A)
NAP  A 350 (-3.2A)
NAP  A 350 (-3.5A)
 0.26A 4yvvA-1c9wA:
46.1		 4yvvA-1c9wA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVX_A_GMRA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 12 TYR A  48
TRP A  79
HIS A 110
LEU A 115
ASN A 160
 NAP  A 350 (-4.8A)
None
NAP  A 350 (-4.0A)
None
NAP  A 350 (-3.2A)
 0.36A 4yvxA-1c9wA:
45.6		 4yvxA-1c9wA:
46.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVX_B_GMRB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 12 TYR A  48
TRP A  79
HIS A 110
LEU A 115
ASN A 160
 NAP  A 350 (-4.8A)
None
NAP  A 350 (-4.0A)
None
NAP  A 350 (-3.2A)
 0.35A 4yvxB-1c9wA:
45.6		 4yvxB-1c9wA:
46.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 12 LEU A 212
ASN A 216
TYR A  39
LEU A  17
GLY A  18
 NAP  A 350 (-3.7A)
NAP  A 350 (-3.1A)
None
None
NAP  A 350 (-3.1A)
 1.28A 5b8hA-1c9wA:
undetectable
5b8hB-1c9wA:
undetectable		 5b8hA-1c9wA:
20.87
5b8hB-1c9wA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 8 ILE A 109
PHE A 137
VAL A 158
GLU A 308
 None
 1.15A 5dqyA-1c9wA:
0.0		 5dqyA-1c9wA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		3 / 3 HIS A 187
SER A 210
ARG A 217
 None
NAP  A 350 (-2.4A)
None
 0.92A 5u63A-1c9wA:
undetectable		 5u63A-1c9wA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 9 LEU A 170
ARG A 168
PHE A 137
VAL A 158
ILE A 166
 None
 1.20A 6ef6A-1c9wA:
0.0		 6ef6A-1c9wA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		4 / 5 PHE A 276
VAL A  33
PRO A 261
VAL A 275
 None
None
NAP  A 350 (-4.9A)
None
 1.36A 6ekzA-1c9wA:
0.0		 6ekzA-1c9wA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 1c9w CHO REDUCTASE
(Cricetulus
griseus) 		5 / 12 GLY A 114
VAL A 130
GLY A 157
ASN A 305
GLN A 165
 None
 1.00A 6gngA-1c9wA:
undetectable		 6gngA-1c9wA:
19.80