SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cau'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 1cau CANAVALIN
(Canavalia
ensiformis) 		4 / 7 LEU B 265
TYR B 258
THR B 269
ASN B 299
 None
 0.99A 1afsA-1cauB:
undetectable		 1afsA-1cauB:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 1cau CANAVALIN
(Canavalia
ensiformis) 		4 / 7 LEU B 265
TYR B 258
THR B 269
ASN B 299
 None
 0.99A 1afsB-1cauB:
undetectable		 1afsB-1cauB:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 1cau CANAVALIN
(Canavalia
ensiformis) 		5 / 12 LEU B 356
LEU B 340
LEU B 306
MET B 288
GLY B 311
 None
 1.23A 1g50B-1cauB:
undetectable		 1g50B-1cauB:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 1cau CANAVALIN
(Canavalia
ensiformis) 		5 / 11 LEU B 356
LEU B 340
LEU B 306
MET B 288
GLY B 311
 None
 1.22A 1g50C-1cauB:
0.0		 1g50C-1cauB:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 1cau CANAVALIN
(Canavalia
ensiformis) 		5 / 12 LEU B 356
PHE B 294
LEU B 362
MET B 288
ARG B 376
 None
 1.15A 2qd4B-1cauB:
undetectable		 2qd4B-1cauB:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_2
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 1cau CANAVALIN
(Canavalia
ensiformis) 		4 / 4 PRO B 256
LEU B 265
HIS B 297
LEU B 379
 None
 1.40A 3vw7A-1cauB:
0.0		 3vw7A-1cauB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1cau CANAVALIN
(Canavalia
ensiformis) 		5 / 12 ALA B 355
ASN B 284
LEU B 286
MET B 288
GLY B 263
 None
 1.21A 4r38A-1cauB:
undetectable		 4r38A-1cauB:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1cau CANAVALIN
(Canavalia
ensiformis) 		5 / 12 ALA B 355
ASN B 284
LEU B 286
MET B 288
GLY B 263
 None
 1.19A 4r38C-1cauB:
undetectable		 4r38C-1cauB:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1cau CANAVALIN
(Canavalia
ensiformis) 		5 / 12 ALA B 355
ASN B 284
LEU B 286
MET B 288
GLY B 263
 None
 1.18A 4r38D-1cauB:
undetectable		 4r38D-1cauB:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 1cau CANAVALIN
(Canavalia
ensiformis) 		5 / 9 ASN B 299
GLY B 366
ILE B 367
THR B 269
PRO B 270
 None
 1.17A 5kr2C-1cauB:
undetectable		 5kr2C-1cauB:
21.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CB4_A_BEZA501_0
(CANAVALIN)		 1cau CANAVALIN
(Canavalia
ensiformis) 		6 / 8 ASN B 284
LEU B 286
HIS B 297
ASN B 299
ILE B 348
ARG B 376
 None
 0.73A 6cb4A-1cauB:
13.3		 6cb4A-1cauB:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CB4_A_BEZA501_0
(CANAVALIN)		 1cau CANAVALIN
(Canavalia
ensiformis) 		7 / 8 ASN B 284
LEU B 286
HIS B 297
ASN B 299
VAL B 304
LEU B 306
ILE B 348
 None
 0.36A 6cb4A-1cauB:
13.3		 6cb4A-1cauB:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CB4_A_BEZA502_0
(CANAVALIN)		 1cau CANAVALIN
(Canavalia
ensiformis) 		4 / 4 GLY B 263
LYS B 264
GLN B 287
ASN B 289
 None
 0.60A 6cb4A-1cauB:
13.3		 6cb4A-1cauB:
99.46