SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cbk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 1cbk PROTEIN
(7,8-DIHYDRO-6-HYDRO
XYMETHYLPTERIN-PYROP
HOSPHOKINASE)
(Haemophilus
influenzae) 		4 / 8 ASN A  11
ASP A 117
GLY A   9
ASP A  95
 None
None
ROI  A 601 ( 3.8A)
ROI  A 601 (-4.6A)
 0.90A 1bu5B-1cbkA:
undetectable		 1bu5B-1cbkA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1cbk PROTEIN
(7,8-DIHYDRO-6-HYDRO
XYMETHYLPTERIN-PYROP
HOSPHOKINASE)
(Haemophilus
influenzae) 		5 / 12 GLY A 102
HIS A 119
LEU A  70
LEU A 128
LEU A 137
 None
 1.37A 1fm6D-1cbkA:
undetectable		 1fm6D-1cbkA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1cbk PROTEIN
(7,8-DIHYDRO-6-HYDRO
XYMETHYLPTERIN-PYROP
HOSPHOKINASE)
(Haemophilus
influenzae) 		3 / 3 HIS A 115
ASP A  95
ASN A  11
 None
ROI  A 601 (-4.6A)
None
 0.68A 1wg8B-1cbkA:
undetectable		 1wg8B-1cbkA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 1cbk PROTEIN
(7,8-DIHYDRO-6-HYDRO
XYMETHYLPTERIN-PYROP
HOSPHOKINASE)
(Haemophilus
influenzae) 		5 / 10 LEU A  94
LEU A  19
LEU A  23
ILE A  26
ALA A   7
 None
 1.15A 2bxeB-1cbkA:
undetectable		 2bxeB-1cbkA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 1cbk PROTEIN
(7,8-DIHYDRO-6-HYDRO
XYMETHYLPTERIN-PYROP
HOSPHOKINASE)
(Haemophilus
influenzae) 		5 / 12 LEU A  94
LEU A  19
LEU A  23
ILE A  26
ALA A   7
 None
 1.12A 2bxpA-1cbkA:
undetectable		 2bxpA-1cbkA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 1cbk PROTEIN
(7,8-DIHYDRO-6-HYDRO
XYMETHYLPTERIN-PYROP
HOSPHOKINASE)
(Haemophilus
influenzae) 		6 / 12 LEU A  94
LEU A  19
LEU A  23
ILE A  26
ILE A   6
ALA A   7
 None
 1.05A 2bxqA-1cbkA:
undetectable		 2bxqA-1cbkA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 1cbk PROTEIN
(7,8-DIHYDRO-6-HYDRO
XYMETHYLPTERIN-PYROP
HOSPHOKINASE)
(Haemophilus
influenzae) 		5 / 5 LEU A  94
LEU A  23
ILE A  26
ILE A   6
ALA A   7
 None
 1.15A 2i2zA-1cbkA:
undetectable		 2i2zA-1cbkA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1cbk PROTEIN
(7,8-DIHYDRO-6-HYDRO
XYMETHYLPTERIN-PYROP
HOSPHOKINASE)
(Haemophilus
influenzae) 		4 / 6 LEU A  71
ILE A  98
ILE A 131
LEU A  34
 None
 0.96A 2xkwB-1cbkA:
undetectable		 2xkwB-1cbkA:
20.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 1cbk PROTEIN
(7,8-DIHYDRO-6-HYDRO
XYMETHYLPTERIN-PYROP
HOSPHOKINASE)
(Haemophilus
influenzae) 		5 / 8 GLY A   9
LEU A  46
TYR A  54
ASN A  56
PHE A 123
 ROI  A 601 ( 3.8A)
ROI  A 601 (-4.2A)
ROI  A 601 (-3.6A)
ROI  A 601 (-3.0A)
ROI  A 601 (-3.4A)
 0.45A 4m5mA-1cbkA:
26.3		 4m5mA-1cbkA:
56.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 1cbk PROTEIN
(7,8-DIHYDRO-6-HYDRO
XYMETHYLPTERIN-PYROP
HOSPHOKINASE)
(Haemophilus
influenzae) 		5 / 8 GLY A   9
TYR A  54
ASN A  56
ARG A  92
PHE A 123
 ROI  A 601 ( 3.8A)
ROI  A 601 (-3.6A)
ROI  A 601 (-3.0A)
SO4  A 501 ( 2.9A)
ROI  A 601 (-3.4A)
 0.36A 4m5mA-1cbkA:
26.3		 4m5mA-1cbkA:
56.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 1cbk PROTEIN
(7,8-DIHYDRO-6-HYDRO
XYMETHYLPTERIN-PYROP
HOSPHOKINASE)
(Haemophilus
influenzae) 		4 / 6 ILE A 113
PRO A 114
ILE A 125
VAL A 124
 None
 0.72A 4zj8A-1cbkA:
undetectable		 4zj8A-1cbkA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA501_0
(CANAVALIN)		 1cbk PROTEIN
(7,8-DIHYDRO-6-HYDRO
XYMETHYLPTERIN-PYROP
HOSPHOKINASE)
(Haemophilus
influenzae) 		4 / 8 LEU A 100
VAL A 124
LEU A 128
ILE A 125
 None
 0.57A 6cb4A-1cbkA:
undetectable		 6cb4A-1cbkA:
17.63