SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cby'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1cby DELTA-ENDOTOXIN CYTB
(Bacillus
thuringiensis) 		4 / 4 THR A  95
LEU A 220
LEU A  60
GLN A  56
 None
 0.89A 1fbmA-1cbyA:
0.0		 1fbmA-1cbyA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1cby DELTA-ENDOTOXIN CYTB
(Bacillus
thuringiensis) 		4 / 5 THR A  95
LEU A 220
LEU A  60
GLN A  56
 None
 0.90A 1fbmE-1cbyA:
undetectable		 1fbmE-1cbyA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_1
(ORPHAN NUCLEAR
RECEPTOR PXR)		 1cby DELTA-ENDOTOXIN CYTB
(Bacillus
thuringiensis) 		5 / 12 VAL A 193
LEU A 189
GLN A 149
TRP A 157
PHE A 173
 None
 1.46A 1skxA-1cbyA:
0.0		 1skxA-1cbyA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1cby DELTA-ENDOTOXIN CYTB
(Bacillus
thuringiensis) 		4 / 5 PHE A  75
LEU A 220
PHE A  43
SER A 174
 None
 1.28A 1wrkB-1cbyA:
undetectable		 1wrkB-1cbyA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1cby DELTA-ENDOTOXIN CYTB
(Bacillus
thuringiensis) 		4 / 7 TYR A 213
THR A 165
VAL A 202
ASP A 196
 None
 1.06A 2cppA-1cbyA:
0.0		 2cppA-1cbyA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 1cby DELTA-ENDOTOXIN CYTB
(Bacillus
thuringiensis) 		5 / 11 ILE A  87
LEU A  81
ASN A  76
LEU A 222
ILE A  92
 None
 1.26A 3a50B-1cbyA:
undetectable		 3a50B-1cbyA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 1cby DELTA-ENDOTOXIN CYTB
(Bacillus
thuringiensis) 		5 / 11 ILE A  87
LEU A  81
ASN A  76
LEU A 222
ILE A  92
 None
 1.30A 3a50C-1cbyA:
undetectable		 3a50C-1cbyA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 1cby DELTA-ENDOTOXIN CYTB
(Bacillus
thuringiensis) 		4 / 5 ILE A 107
ILE A 101
TYR A 213
GLU A 214
 None
 1.18A 4a99D-1cbyA:
undetectable		 4a99D-1cbyA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1cby DELTA-ENDOTOXIN CYTB
(Bacillus
thuringiensis) 		5 / 12 SER A  38
ASN A 238
ASP A 235
ILE A 236
PHE A  47
 None
 0.96A 4u8vB-1cbyA:
0.0		 4u8vB-1cbyA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1cby DELTA-ENDOTOXIN CYTB
(Bacillus
thuringiensis) 		5 / 12 SER A  38
ASN A 238
ASP A 235
ILE A 236
PHE A  47
 None
 0.98A 4u8yB-1cbyA:
0.1		 4u8yB-1cbyA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 1cby DELTA-ENDOTOXIN CYTB
(Bacillus
thuringiensis) 		4 / 7 ASN A  76
TYR A 168
LEU A 189
PHE A 173
 None
 1.25A 4yv5A-1cbyA:
0.0		 4yv5A-1cbyA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 1cby DELTA-ENDOTOXIN CYTB
(Bacillus
thuringiensis) 		5 / 12 ILE A  83
PRO A 188
LEU A 220
PHE A  64
GLY A  66
 None
 1.02A 5il1A-1cbyA:
undetectable		 5il1A-1cbyA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1cby DELTA-ENDOTOXIN CYTB
(Bacillus
thuringiensis) 		5 / 12 ILE A  83
PRO A 188
LEU A 220
PHE A  64
GLY A  66
 None
 0.97A 5k7uA-1cbyA:
undetectable		 5k7uA-1cbyA:
21.89