SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ccz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		5 / 12 GLU A  74
PHE A  15
VAL A  13
LEU A  67
THR A  68
 None
 1.13A 1oq5A-1cczA:
undetectable		 1oq5A-1cczA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		5 / 9 LEU A  67
LEU A  90
VAL A  35
ALA A  36
PHE A  15
 None
 1.13A 1tbfA-1cczA:
undetectable		 1tbfA-1cczA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 VAL A  92
ARG A  52
VAL A  13
GLU A  72
 None
 0.97A 1zzrA-1cczA:
0.0
1zzrB-1cczA:
0.0		 1zzrA-1cczA:
17.72
1zzrB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.98A 1zzrA-1cczA:
0.0
1zzrB-1cczA:
0.0		 1zzrA-1cczA:
17.72
1zzrB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 VAL A  92
ARG A  52
VAL A  13
GLU A  72
 None
 0.97A 1zzuA-1cczA:
0.0
1zzuB-1cczA:
0.0		 1zzuA-1cczA:
17.72
1zzuB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.98A 1zzuA-1cczA:
0.0
1zzuB-1cczA:
0.0		 1zzuA-1cczA:
17.72
1zzuB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 VAL A  92
ARG A  52
VAL A  13
GLU A  72
 None
 0.98A 3dqrA-1cczA:
0.0
3dqrB-1cczA:
0.0		 3dqrA-1cczA:
17.72
3dqrB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 VAL A  92
ARG A  52
VAL A  13
GLU A  72
 None
 0.96A 3jx2A-1cczA:
0.0
3jx2B-1cczA:
0.0		 3jx2A-1cczA:
17.72
3jx2B-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.96A 3jx2A-1cczA:
0.0
3jx2B-1cczA:
0.0		 3jx2A-1cczA:
17.72
3jx2B-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 VAL A  92
ARG A  52
VAL A  13
GLU A  72
 None
 1.00A 3jx3A-1cczA:
0.0
3jx3B-1cczA:
0.0		 3jx3A-1cczA:
17.72
3jx3B-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.96A 3jx3A-1cczA:
0.0
3jx3B-1cczA:
0.0		 3jx3A-1cczA:
17.72
3jx3B-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.99A 3jx4A-1cczA:
0.0
3jx4B-1cczA:
0.0		 3jx4A-1cczA:
17.72
3jx4B-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 VAL A  92
ARG A  52
VAL A  13
GLU A  72
 None
 0.97A 3jx5A-1cczA:
0.0
3jx5B-1cczA:
0.0		 3jx5A-1cczA:
17.72
3jx5B-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.98A 3jx5A-1cczA:
0.0
3jx5B-1cczA:
0.0		 3jx5A-1cczA:
17.72
3jx5B-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 VAL A  92
ARG A  52
VAL A  13
GLU A  72
 None
 0.92A 3jx6A-1cczA:
0.0
3jx6B-1cczA:
0.0		 3jx6A-1cczA:
17.72
3jx6B-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.94A 3jx6A-1cczA:
0.0
3jx6B-1cczA:
0.0		 3jx6A-1cczA:
17.72
3jx6B-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 VAL A  92
ARG A  52
VAL A  13
GLU A  72
 None
 0.92A 3nljA-1cczA:
0.0
3nljB-1cczA:
0.0		 3nljA-1cczA:
17.72
3nljB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.92A 3nljA-1cczA:
0.0
3nljB-1cczA:
0.0		 3nljA-1cczA:
17.72
3nljB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 VAL A  92
ARG A  52
VAL A  13
GLU A  72
 None
 0.95A 3nlpA-1cczA:
0.0
3nlpB-1cczA:
0.0		 3nlpA-1cczA:
17.72
3nlpB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.98A 3nlpA-1cczA:
0.0
3nlpB-1cczA:
0.0		 3nlpA-1cczA:
17.72
3nlpB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 8 VAL A  92
ARG A  52
VAL A  13
GLU A  72
 None
 0.91A 3nlqA-1cczA:
0.0
3nlqB-1cczA:
0.0		 3nlqA-1cczA:
17.72
3nlqB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.93A 3nlqA-1cczA:
0.0
3nlqB-1cczA:
0.0		 3nlqA-1cczA:
17.72
3nlqB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 VAL A  92
ARG A  52
VAL A  13
GLU A  72
 None
 0.96A 3nlrA-1cczA:
0.0
3nlrB-1cczA:
0.0		 3nlrA-1cczA:
17.72
3nlrB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 8 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.94A 3nlrA-1cczA:
0.0
3nlrB-1cczA:
0.0		 3nlrA-1cczA:
17.72
3nlrB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 VAL A  92
ARG A  52
VAL A  13
GLU A  72
 None
 0.99A 4cx3A-1cczA:
0.0
4cx3B-1cczA:
0.0		 4cx3A-1cczA:
17.72
4cx3B-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.97A 4cx3A-1cczA:
0.0
4cx3B-1cczA:
0.0		 4cx3A-1cczA:
17.72
4cx3B-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 VAL A  92
ARG A  52
VAL A  13
GLU A  72
 None
 0.99A 4cx4A-1cczA:
0.0
4cx4B-1cczA:
0.0		 4cx4A-1cczA:
17.72
4cx4B-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.97A 4cx4A-1cczA:
0.0
4cx4B-1cczA:
0.0		 4cx4A-1cczA:
17.72
4cx4B-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.92A 5addA-1cczA:
0.0
5addB-1cczA:
0.0		 5addA-1cczA:
17.72
5addB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.91A 5adeA-1cczA:
0.0
5adeB-1cczA:
0.0		 5adeA-1cczA:
17.72
5adeB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 VAL A  92
ARG A  52
VAL A  13
GLU A  72
 None
 0.98A 5g0pA-1cczA:
0.0
5g0pB-1cczA:
0.0		 5g0pA-1cczA:
17.72
5g0pB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 7 GLU A  72
VAL A  92
ARG A  52
VAL A  13
 None
 0.99A 5g0pA-1cczA:
0.0
5g0pB-1cczA:
0.0		 5g0pA-1cczA:
17.72
5g0pB-1cczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 1ccz PROTEIN (CD58)
(Homo
sapiens) 		4 / 6 VAL A  26
ASN A  81
PRO A  80
ILE A  82
 None
 1.04A 6h7uA-1cczA:
undetectable		 6h7uA-1cczA:
15.95