SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cd1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 1cd1 CD1
(Mus
musculus) 		4 / 7 LEU A 238
THR A 250
SER A 211
VAL A 207
 None
 0.98A 1tyrB-1cd1A:
0.2		 1tyrB-1cd1A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 1cd1 CD1
(Mus
musculus) 		4 / 8 ARG A 204
HIS A 209
SER A 194
VAL A 196
 None
 1.27A 1u1jA-1cd1A:
undetectable		 1u1jA-1cd1A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_A_PXLA313_1
(PYRIDOXAL KINASE)		 1cd1 CD1
(Mus
musculus) 		4 / 4 SER A  41
HIS A  38
THR A  50
VAL A  30
 None
 1.39A 3fhxA-1cd1A:
undetectable		 3fhxA-1cd1A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1cd1 CD1
(Mus
musculus) 		4 / 5 THR A  78
SER A  16
SER A  28
ARG A  74
 None
 1.39A 3hlwB-1cd1A:
0.0		 3hlwB-1cd1A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1cd1 CD1
(Mus
musculus) 		4 / 7 THR A 135
ILE A  98
GLN A  99
VAL A 118
 None
 0.92A 6cduF-1cd1A:
3.1
6cduJ-1cd1A:
3.0		 6cduF-1cd1A:
19.65
6cduJ-1cd1A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1cd1 CD1
(Mus
musculus) 		4 / 7 ILE A  98
GLN A  99
VAL A 118
THR A 135
 None
 0.94A 6cduF-1cd1A:
3.1
6cduG-1cd1A:
2.3		 6cduF-1cd1A:
19.65
6cduG-1cd1A:
19.65