SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cdo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 1cdo ALCOHOL
DEHYDROGENASE
(Gadus
morhua) 		3 / 3 TRP A  15
ALA A  12
VAL A  22
 None
 0.86A 1c4dA-1cdoA:
undetectable
1c4dB-1cdoA:
undetectable		 1c4dA-1cdoA:
5.26
1c4dB-1cdoA:
5.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 1cdo ALCOHOL
DEHYDROGENASE
(Gadus
morhua) 		5 / 11 CYH A  46
HIS A  68
MET A 124
LEU A 142
CYH A 175
 ZN  A 376 ( 2.2A)
ZN  A 376 (-3.5A)
None
None
ZN  A 376 ( 2.2A)
 0.62A 1ee2A-1cdoA:
58.1		 1ee2A-1cdoA:
55.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 1cdo ALCOHOL
DEHYDROGENASE
(Gadus
morhua) 		5 / 11 CYH A  46
HIS A  68
MET A 124
LEU A 142
CYH A 175
 ZN  A 376 ( 2.2A)
ZN  A 376 (-3.5A)
None
None
ZN  A 376 ( 2.2A)
 0.56A 1ee2B-1cdoA:
58.2		 1ee2B-1cdoA:
55.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1cdo ALCOHOL
DEHYDROGENASE
(Gadus
morhua) 		4 / 8 THR A 259
VAL A 242
ASP A 240
VAL A 223
 None
 0.98A 1iwiA-1cdoA:
undetectable		 1iwiA-1cdoA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1cdo ALCOHOL
DEHYDROGENASE
(Gadus
morhua) 		3 / 3 ILE A  38
ILE A  36
THR A 146
 None
 0.47A 1rg7A-1cdoA:
undetectable		 1rg7A-1cdoA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1cdo ALCOHOL
DEHYDROGENASE
(Gadus
morhua) 		5 / 12 ALA A  71
ILE A  40
ILE A  91
VAL A 158
ALA A 157
 None
 1.02A 1uduB-1cdoA:
undetectable		 1uduB-1cdoA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 1cdo ALCOHOL
DEHYDROGENASE
(Gadus
morhua) 		3 / 3 ASP A 337
ILE A 161
VAL A 177
 None
 0.62A 2avvD-1cdoA:
0.0		 2avvD-1cdoA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 1cdo ALCOHOL
DEHYDROGENASE
(Gadus
morhua) 		4 / 8 PHE A 141
GLY A  61
PHE A  62
SER A 125
 None
 1.04A 3tzfB-1cdoA:
undetectable		 3tzfB-1cdoA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 1cdo ALCOHOL
DEHYDROGENASE
(Gadus
morhua) 		5 / 8 ALA A  71
VAL A 170
PRO A 329
VAL A 328
ILE A  91
 None
 1.29A 4ll3A-1cdoA:
undetectable		 4ll3A-1cdoA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 1cdo ALCOHOL
DEHYDROGENASE
(Gadus
morhua) 		4 / 6 GLY A 320
THR A 179
SER A 178
GLY A 176
 None
NAD  A 375 (-3.1A)
None
None
 0.90A 5k4pA-1cdoA:
0.0		 5k4pA-1cdoA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 1cdo ALCOHOL
DEHYDROGENASE
(Gadus
morhua) 		5 / 12 LEU A 374
GLY A  70
GLY A  44
VAL A 371
ARG A 349
 None
 1.12A 5o4yD-1cdoA:
undetectable
5o4yE-1cdoA:
0.0		 5o4yD-1cdoA:
5.65
5o4yE-1cdoA:
15.43