SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cee'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens) 		4 / 4 ILE B   9
LEU A  79
VAL A  77
ILE A   4
 None
 0.90A 1fm6D-1ceeB:
undetectable		 1fm6D-1ceeB:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
(Homo
sapiens) 		5 / 8 VAL A  98
VAL A  93
SER A  89
ILE A 137
LEU A 112
 None
 1.35A 1igxA-1ceeA:
0.0		 1igxA-1ceeA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens) 		5 / 11 THR A  17
TYR A  40
PHE A  56
VAL B  31
PHE B  42
 MG  A 180 ( 3.4A)
None
None
None
None
 1.03A 1q23G-1ceeA:
0.0		 1q23G-1ceeA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens) 		5 / 11 THR A  17
TYR A  40
PHE A  56
VAL B  31
PHE B  42
 MG  A 180 ( 3.4A)
None
None
None
None
 1.03A 1q23J-1ceeA:
undetectable		 1q23J-1ceeA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
(Homo
sapiens) 		3 / 3 ASP A 118
VAL A  84
PRO A 139
 GCP  A 181 (-2.5A)
None
None
 0.57A 2avvA-1ceeA:
0.0		 2avvA-1ceeA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 VAL A   9
CYH A   6
LEU A  79
ALA A 172
ILE A   4
 None
 0.92A 3a35A-1ceeA:
0.0		 3a35A-1ceeA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 VAL A   9
CYH A   6
LEU A  79
ALA A 172
ILE A   4
 None
 0.95A 3a35B-1ceeA:
undetectable		 3a35B-1ceeA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 VAL A   9
CYH A   6
LEU A  79
ALA A 172
ILE A   4
 None
 0.93A 3a3bA-1ceeA:
0.0		 3a3bA-1ceeA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens;
Homo
sapiens) 		4 / 8 HIS B  17
THR A  25
HIS B  20
LEU A 165
 None
 1.18A 3wg7A-1ceeB:
undetectable
3wg7C-1ceeB:
undetectable
3wg7P-1ceeB:
undetectable		 3wg7A-1ceeB:
8.17
3wg7C-1ceeB:
10.43
3wg7P-1ceeB:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens;
Homo
sapiens) 		4 / 8 LEU A 165
HIS B  17
THR A  25
HIS B  20
 None
 1.20A 3wg7C-1ceeA:
undetectable
3wg7N-1ceeA:
undetectable
3wg7P-1ceeA:
0.0		 3wg7C-1ceeA:
21.43
3wg7N-1ceeA:
15.94
3wg7P-1ceeA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens;
Homo
sapiens) 		4 / 8 HIS B  17
THR A  25
HIS B  20
LEU A 165
 None
 1.19A 3x2qA-1ceeB:
undetectable
3x2qC-1ceeB:
undetectable
3x2qP-1ceeB:
undetectable		 3x2qA-1ceeB:
8.17
3x2qC-1ceeB:
10.43
3x2qP-1ceeB:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_F_PARF500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens) 		5 / 11 PHE B  42
THR A  58
SER A  71
GLU A 100
GLY A  60
 None
 1.49A 4qb9F-1ceeB:
undetectable		 4qb9F-1ceeB:
8.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens;
Homo
sapiens) 		4 / 8 HIS B  17
THR A  25
HIS B  20
LEU A 165
 None
 1.22A 5b1aA-1ceeB:
undetectable
5b1aC-1ceeB:
undetectable
5b1aP-1ceeB:
undetectable		 5b1aA-1ceeB:
8.17
5b1aC-1ceeB:
10.43
5b1aP-1ceeB:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens;
Homo
sapiens) 		4 / 8 HIS B  17
THR A  25
HIS B  20
LEU A 165
 None
 1.22A 5b3sA-1ceeB:
undetectable
5b3sC-1ceeB:
undetectable
5b3sP-1ceeB:
undetectable		 5b3sA-1ceeB:
8.17
5b3sC-1ceeB:
10.43
5b3sP-1ceeB:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens) 		3 / 3 THR A  52
THR A  43
PHE B  15
 None
 0.82A 5cxvA-1ceeA:
undetectable		 5cxvA-1ceeA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
(Homo
sapiens) 		3 / 3 LYS A 153
LEU A  79
ILE A 173
 None
 0.78A 5kc0A-1ceeA:
0.4		 5kc0A-1ceeA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens;
Homo
sapiens) 		4 / 8 HIS B  17
THR A  25
HIS B  20
LEU A 165
 None
 1.20A 5xdqA-1ceeB:
undetectable
5xdqC-1ceeB:
undetectable
5xdqP-1ceeB:
undetectable		 5xdqA-1ceeB:
8.17
5xdqC-1ceeB:
10.43
5xdqP-1ceeB:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens;
Homo
sapiens) 		4 / 7 LEU A 165
HIS B  17
THR A  25
HIS B  20
 None
 1.25A 5z84C-1ceeA:
undetectable
5z84N-1ceeA:
undetectable
5z84P-1ceeA:
undetectable		 5z84C-1ceeA:
21.43
5z84N-1ceeA:
15.94
5z84P-1ceeA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens;
Homo
sapiens) 		4 / 8 HIS B  17
THR A  25
HIS B  20
LEU A 165
 None
 1.22A 5z85A-1ceeB:
undetectable
5z85C-1ceeB:
undetectable
5z85P-1ceeB:
undetectable		 5z85A-1ceeB:
8.17
5z85C-1ceeB:
10.43
5z85P-1ceeB:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens;
Homo
sapiens) 		4 / 7 LEU A 165
HIS B  17
THR A  25
HIS B  20
 None
 1.25A 5z85C-1ceeA:
0.0
5z85N-1ceeA:
undetectable
5z85P-1ceeA:
0.0		 5z85C-1ceeA:
21.43
5z85N-1ceeA:
15.94
5z85P-1ceeA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens;
Homo
sapiens) 		4 / 8 HIS B  17
THR A  25
HIS B  20
LEU A 165
 None
 1.22A 5z86A-1ceeB:
undetectable
5z86C-1ceeB:
undetectable
5z86P-1ceeB:
undetectable		 5z86A-1ceeB:
8.17
5z86C-1ceeB:
10.43
5z86P-1ceeB:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens;
Homo
sapiens) 		4 / 8 HIS B  17
THR A  25
HIS B  20
LEU A 165
 None
 1.21A 5zcoA-1ceeB:
undetectable
5zcoC-1ceeB:
undetectable
5zcoP-1ceeB:
undetectable		 5zcoA-1ceeB:
8.17
5zcoC-1ceeB:
10.43
5zcoP-1ceeB:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
WISKOTT-ALDRICH
SYNDROME PROTEIN
WASP
(Homo
sapiens;
Homo
sapiens) 		4 / 8 HIS B  17
THR A  25
HIS B  20
LEU A 165
 None
 1.21A 5zcqA-1ceeB:
undetectable
5zcqC-1ceeB:
undetectable
5zcqP-1ceeB:
undetectable		 5zcqA-1ceeB:
8.17
5zcqC-1ceeB:
10.43
5zcqP-1ceeB:
10.43