SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cf0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1cf0 PROTEIN (PROFILIN)
(Homo
sapiens) 		4 / 8 THR A 101
ASP A  86
SER A  84
TYR A 128
 None
 1.12A 2xz5A-1cf0A:
0.0
2xz5C-1cf0A:
0.0		 2xz5A-1cf0A:
20.09
2xz5C-1cf0A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 1cf0 PROTEIN (PROFILIN)
(Homo
sapiens) 		4 / 7 LEU A  50
LEU A  65
SER A  71
THR A  97
 None
 1.05A 3lm8B-1cf0A:
undetectable
3lm8D-1cf0A:
undetectable		 3lm8B-1cf0A:
19.65
3lm8D-1cf0A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 1cf0 PROTEIN (PROFILIN)
(Homo
sapiens) 		4 / 6 LEU A  87
VAL A 100
MET A 113
PHE A  39
 None
 1.09A 3soaA-1cf0A:
0.7		 3soaA-1cf0A:
15.37