SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cf2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 11 VAL P 227
GLY P 157
VAL P 239
ASP P 235
ILE P 236
 None
 1.05A 1phgA-1cf2P:
undetectable		 1phgA-1cf2P:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 10 ALA P 265
MET P 262
LEU P 217
GLN P 300
ASP P 303
 None
 1.34A 1rlbE-1cf2P:
0.1		 1rlbE-1cf2P:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		4 / 7 ASP P 235
VAL P 239
GLY P 157
THR P 148
 None
 0.75A 1t7iB-1cf2P:
undetectable		 1t7iB-1cf2P:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_2
(POL POLYPROTEIN)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		4 / 7 ASP P 235
VAL P 239
GLY P 157
THR P 148
 None
 0.74A 1t7jB-1cf2P:
undetectable		 1t7jB-1cf2P:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 9 VAL P 227
GLY P 157
VAL P 239
ASP P 235
ILE P 236
 None
 1.09A 2a1oB-1cf2P:
undetectable		 2a1oB-1cf2P:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		4 / 7 THR P 208
LEU P 202
VAL P 198
VAL P 223
 None
 1.04A 2cppA-1cf2P:
undetectable		 2cppA-1cf2P:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 10 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.38A 3fhjB-1cf2P:
undetectable		 3fhjB-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 10 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.39A 3fhjC-1cf2P:
undetectable		 3fhjC-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 9 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.39A 3fhjD-1cf2P:
undetectable		 3fhjD-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 9 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.39A 3fhjF-1cf2P:
undetectable		 3fhjF-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 9 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.37A 3fi0A-1cf2P:
undetectable		 3fi0A-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 9 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.36A 3fi0C-1cf2P:
2.0		 3fi0C-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 9 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.35A 3fi0D-1cf2P:
undetectable		 3fi0D-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 9 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.38A 3fi0F-1cf2P:
1.2		 3fi0F-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 9 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.39A 3fi0H-1cf2P:
undetectable		 3fi0H-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 8 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.36A 3fi0I-1cf2P:
undetectable		 3fi0I-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 9 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.40A 3fi0J-1cf2P:
1.1		 3fi0J-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 9 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.36A 3fi0K-1cf2P:
undetectable		 3fi0K-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 9 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.40A 3fi0L-1cf2P:
undetectable		 3fi0L-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 9 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.39A 3fi0M-1cf2P:
2.3		 3fi0M-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 9 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.33A 3fi0N-1cf2P:
undetectable		 3fi0N-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 9 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.43A 3fi0O-1cf2P:
undetectable		 3fi0O-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 9 GLY P   8
ASP P  84
ILE P  83
VAL P  16
VAL P  12
 NAP  P 340 (-3.2A)
None
None
None
NAP  P 340 (-3.9A)
 1.32A 3fi0R-1cf2P:
undetectable		 3fi0R-1cf2P:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_1
(REPRESSOR PROTEIN
MPHR(A))		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		4 / 5 ASN P 222
ASN P 141
HIS P 194
ALA P 210
 None
SO4  P1001 (-3.5A)
SO4  P1001 (-4.1A)
None
 1.40A 3frqA-1cf2P:
0.0		 3frqA-1cf2P:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_1
(REPRESSOR PROTEIN
MPHR(A))		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		4 / 7 ASN P 222
ASN P 141
HIS P 194
ALA P 210
 None
SO4  P1001 (-3.5A)
SO4  P1001 (-4.1A)
None
 1.41A 3frqB-1cf2P:
0.0		 3frqB-1cf2P:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		3 / 3 ASN P 334
MET P 262
PHE P 276
 None
 1.06A 3g4lD-1cf2P:
undetectable		 3g4lD-1cf2P:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 11 GLY P  30
ASP P  80
ALA P  79
ASP P  49
ILE P  29
 None
 1.33A 3id5B-1cf2P:
5.0		 3id5B-1cf2P:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_F_SAMF301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 11 GLY P  30
ASP P  80
ALA P  79
ASP P  49
ILE P  29
 None
 1.33A 3id5F-1cf2P:
4.9		 3id5F-1cf2P:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		3 / 3 HIS P 219
HIS P 221
ILE P 165
 None
 0.82A 3u52A-1cf2P:
undetectable
3u52C-1cf2P:
0.0		 3u52A-1cf2P:
20.70
3u52C-1cf2P:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 12 ILE P 261
GLY P 144
THR P 148
ILE P 247
VAL P 246
 None
 0.94A 4c9lA-1cf2P:
undetectable		 4c9lA-1cf2P:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 12 ILE P 261
GLY P 144
THR P 148
ILE P 247
VAL P 246
 None
 0.92A 4c9lB-1cf2P:
undetectable		 4c9lB-1cf2P:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 12 ILE P 261
GLY P 144
THR P 148
ILE P 247
VAL P 246
 None
 1.00A 4c9oA-1cf2P:
undetectable		 4c9oA-1cf2P:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 12 ILE P 261
GLY P 144
THR P 148
ILE P 247
VAL P 246
 None
 0.99A 4c9oB-1cf2P:
undetectable		 4c9oB-1cf2P:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		4 / 5 LEU P 316
ILE P  20
ALA P 311
MET P  26
 None
 1.00A 4dc3B-1cf2P:
7.5		 4dc3B-1cf2P:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		4 / 8 SER P 155
LEU P 152
PHE P 240
PRO P 231
 None
 1.01A 4j7uD-1cf2P:
4.9		 4j7uD-1cf2P:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		4 / 8 THR P 208
LEU P 202
VAL P 198
VAL P 223
 None
 1.01A 4l4aA-1cf2P:
undetectable		 4l4aA-1cf2P:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		4 / 8 THR P 208
LEU P 202
VAL P 198
VAL P 223
 None
 1.02A 4l4dA-1cf2P:
0.0		 4l4dA-1cf2P:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		4 / 8 THR P 208
LEU P 202
VAL P 198
VAL P 223
 None
 1.02A 4l4eA-1cf2P:
undetectable		 4l4eA-1cf2P:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		3 / 3 VAL P 138
SER P 139
THR P 142
 None
SO4  P1001 (-2.7A)
None
 0.48A 4luhA-1cf2P:
0.4		 4luhA-1cf2P:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		4 / 6 GLY P  13
TYR P   9
ALA P  17
ARG P 272
 None
 1.22A 4yshB-1cf2P:
0.0		 4yshB-1cf2P:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		5 / 12 ILE P 236
LEU P 149
VAL P 223
PHE P 240
THR P 148
 None
 1.19A 5byjA-1cf2P:
2.3		 5byjA-1cf2P:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		3 / 3 ASP P 197
ASN P 141
PHE P 107
 None
SO4  P1001 (-3.5A)
None
 0.88A 5jglB-1cf2P:
3.2		 5jglB-1cf2P:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		4 / 8 VAL P 305
GLY P   8
GLN P 108
THR P  86
 None
NAP  P 340 (-3.2A)
None
NAP  P 340 (-4.6A)
 1.03A 5syjA-1cf2P:
0.0		 5syjA-1cf2P:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHD_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		4 / 4 ARG P 270
PHE P 276
ASP P 303
LEU P 248
 None
 1.37A 5uhdC-1cf2P:
0.0		 5uhdC-1cf2P:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		4 / 9 VAL P 298
HIS P 299
ASP P 303
SER P 119
 None
 0.95A 6c2mD-1cf2P:
undetectable		 6c2mD-1cf2P:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 1cf2 PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Methanothermus
fervidus) 		4 / 7 SER P 124
THR P 135
ILE P 315
ALA P 314
 None
 0.72A 6ma7A-1cf2P:
0.0		 6ma7A-1cf2P:
14.57