SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cf7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_E_TMQE202_1
(DIHYDROFOLATE
REDUCTASE)		 1cf7 PROTEIN
(TRANSCRIPTION
FACTOR DP-2)
PROTEIN
(TRANSCRIPTION
FACTOR E2F-4)
(Homo
sapiens) 		5 / 12 ILE B 136
ALA B 126
LEU A  70
LEU B 148
ILE B 135
 None
 1.04A 4m2xE-1cf7B:
undetectable		 4m2xE-1cf7B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 1cf7 PROTEIN
(TRANSCRIPTION
FACTOR DP-2)
(Homo
sapiens) 		3 / 3 THR B 102
ASN B 103
SER B 104
 None
 0.77A 4tvtA-1cf7B:
undetectable		 4tvtA-1cf7B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 1cf7 PROTEIN
(TRANSCRIPTION
FACTOR E2F-4)
(Homo
sapiens) 		4 / 6 THR A  49
ASP A  48
LEU A  45
ASP A  42
 None
 1.10A 5tdzA-1cf7A:
undetectable		 5tdzA-1cf7A:
11.11