SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cfb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 1cfb DROSOPHILA
NEUROGLIAN
(Drosophila
melanogaster) 		4 / 5 ILE A 740
THR A 653
THR A 656
PHE A 651
 NA  A   5 ( 4.8A)
None
None
None
 1.21A 3snfA-1cfbA:
undetectable		 3snfA-1cfbA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1cfb DROSOPHILA
NEUROGLIAN
(Drosophila
melanogaster) 		3 / 3 GLN A 709
THR A 708
THR A 707
 None
 0.67A 4fu9A-1cfbA:
0.0		 4fu9A-1cfbA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1cfb DROSOPHILA
NEUROGLIAN
(Drosophila
melanogaster) 		3 / 3 GLN A 709
THR A 708
THR A 707
 None
 0.68A 4fufA-1cfbA:
0.0		 4fufA-1cfbA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1cfb DROSOPHILA
NEUROGLIAN
(Drosophila
melanogaster) 		4 / 8 ALA A 803
ASN A 766
ILE A 767
VAL A 712
 None
 0.81A 4r20A-1cfbA:
undetectable		 4r20A-1cfbA:
16.84