SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cfv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 1cfv MONOCLONAL ANTIBODY
FV4155
(Mus
musculus) 		4 / 8 HIS L  39
TYR L  41
TYR L  54
SER L  96
 None
 0.81A 1i7zA-1cfvL:
20.3		 1i7zA-1cfvL:
64.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1cfv MONOCLONAL ANTIBODY
FV4155
MONOCLONAL ANTIBODY
FV4155
(Mus
musculus;
Mus
musculus) 		4 / 8 ASP H 107
ASN H 100
SER L  61
ALA H 102
 None
 1.14A 1rqpA-1cfvH:
undetectable		 1rqpA-1cfvH:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 1cfv MONOCLONAL ANTIBODY
FV4155
MONOCLONAL ANTIBODY
FV4155
(Mus
musculus;
Mus
musculus) 		4 / 8 ASP H 107
ASN H 100
SER L  61
ALA H 102
 None
 1.14A 2v7uA-1cfvH:
undetectable		 2v7uA-1cfvH:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 1cfv MONOCLONAL ANTIBODY
FV4155
(Mus
musculus) 		3 / 3 ASN H  74
ALA H  75
LYS H  77
 None
 1.04A 3runA-1cfvH:
0.0		 3runA-1cfvH:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 1cfv MONOCLONAL ANTIBODY
FV4155
(Mus
musculus) 		3 / 3 LYS H  65
ASN H  87
ASP H  62
 None
 0.80A 4o1eA-1cfvH:
undetectable		 4o1eA-1cfvH:
15.88