SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cg2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		5 / 12 LEU A  47
LEU A  50
VAL A  51
SER A 111
VAL A 392
 None
 1.30A 1db1A-1cg2A:
0.2		 1db1A-1cg2A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		5 / 12 LEU A  47
LEU A  50
VAL A  51
SER A 111
VAL A 392
 None
 1.24A 1ie9A-1cg2A:
0.0		 1ie9A-1cg2A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 7 ILE A 216
GLY A 323
PHE A 295
ASN A 292
 None
 0.98A 1oniG-1cg2A:
0.3
1oniI-1cg2A:
0.3		 1oniG-1cg2A:
17.57
1oniI-1cg2A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 GLU A 200
HIS A 112
ASP A 141
GLU A 176
 ZN  A 501 ( 1.9A)
ZN  A 501 ( 3.3A)
ZN  A 500 (-2.4A)
ZN  A 500 ( 2.0A)
 0.83A 1v7zA-1cg2A:
4.7		 1v7zA-1cg2A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 GLU A 200
HIS A 112
ASP A 141
GLU A 176
 ZN  A 501 ( 1.9A)
ZN  A 501 ( 3.3A)
ZN  A 500 (-2.4A)
ZN  A 500 ( 2.0A)
 0.83A 1v7zB-1cg2A:
5.2		 1v7zB-1cg2A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 GLU A 200
HIS A 112
ASP A 141
GLU A 176
 ZN  A 501 ( 1.9A)
ZN  A 501 ( 3.3A)
ZN  A 500 (-2.4A)
ZN  A 500 ( 2.0A)
 0.84A 1v7zC-1cg2A:
4.6		 1v7zC-1cg2A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 GLU A 200
HIS A 112
ASP A 141
GLU A 176
 ZN  A 501 ( 1.9A)
ZN  A 501 ( 3.3A)
ZN  A 500 (-2.4A)
ZN  A 500 ( 2.0A)
 0.84A 1v7zD-1cg2A:
4.9		 1v7zD-1cg2A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 GLU A 200
HIS A 112
ASP A 141
GLU A 176
 ZN  A 501 ( 1.9A)
ZN  A 501 ( 3.3A)
ZN  A 500 (-2.4A)
ZN  A 500 ( 2.0A)
 0.83A 1v7zE-1cg2A:
4.9		 1v7zE-1cg2A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 GLU A 200
HIS A 112
ASP A 141
GLU A 176
 ZN  A 501 ( 1.9A)
ZN  A 501 ( 3.3A)
ZN  A 500 (-2.4A)
ZN  A 500 ( 2.0A)
 0.84A 1v7zF-1cg2A:
5.2		 1v7zF-1cg2A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_B_GBNB914_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		5 / 10 GLY A 212
GLY A 360
THR A 361
ALA A 363
ALA A 364
 None
 1.17A 2ej3B-1cg2A:
undetectable		 2ej3B-1cg2A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		5 / 8 GLY A 212
GLY A 360
THR A 361
ALA A 363
ALA A 364
 None
 1.14A 2ej3C-1cg2A:
0.0		 2ej3C-1cg2A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 4 SER A 210
GLY A 212
HIS A 385
ASP A 114
 None
None
ZN  A 500 ( 3.2A)
None
 1.31A 2oxtC-1cg2A:
undetectable		 2oxtC-1cg2A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 ARG A 324
SER A 182
ILE A 186
ASP A 174
 None
 1.00A 2xadA-1cg2A:
undetectable		 2xadA-1cg2A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 ARG A 324
SER A 182
ILE A 186
ASP A 174
 None
 1.00A 2xadB-1cg2A:
undetectable		 2xadB-1cg2A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 ARG A 324
SER A 182
ILE A 186
ASP A 174
 None
 0.99A 2xadC-1cg2A:
undetectable		 2xadC-1cg2A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 ARG A 324
SER A 182
ILE A 186
ASP A 174
 None
 0.98A 2xadD-1cg2A:
2.3		 2xadD-1cg2A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 GLU A 200
HIS A 112
ASP A 141
GLU A 176
 ZN  A 501 ( 1.9A)
ZN  A 501 ( 3.3A)
ZN  A 500 (-2.4A)
ZN  A 500 ( 2.0A)
 0.87A 3a6jA-1cg2A:
4.7		 3a6jA-1cg2A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 7 GLU A 200
HIS A 112
ASP A 141
GLU A 176
 ZN  A 501 ( 1.9A)
ZN  A 501 ( 3.3A)
ZN  A 500 (-2.4A)
ZN  A 500 ( 2.0A)
 0.87A 3a6jB-1cg2A:
4.7		 3a6jB-1cg2A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 GLU A 200
HIS A 112
ASP A 141
GLU A 176
 ZN  A 501 ( 1.9A)
ZN  A 501 ( 3.3A)
ZN  A 500 (-2.4A)
ZN  A 500 ( 2.0A)
 0.87A 3a6jC-1cg2A:
4.8		 3a6jC-1cg2A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 GLU A 200
HIS A 112
ASP A 141
GLU A 176
 ZN  A 501 ( 1.9A)
ZN  A 501 ( 3.3A)
ZN  A 500 (-2.4A)
ZN  A 500 ( 2.0A)
 0.88A 3a6jE-1cg2A:
4.6		 3a6jE-1cg2A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 GLU A 200
HIS A 112
ASP A 141
GLU A 176
 ZN  A 501 ( 1.9A)
ZN  A 501 ( 3.3A)
ZN  A 500 (-2.4A)
ZN  A 500 ( 2.0A)
 0.87A 3a6jF-1cg2A:
4.7		 3a6jF-1cg2A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 5 TYR A 391
PRO A 137
THR A 115
THR A 202
 None
 1.39A 3q07A-1cg2A:
undetectable		 3q07A-1cg2A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 5 TYR A 391
PRO A 137
THR A 115
THR A 202
 None
 1.37A 3q07B-1cg2A:
undetectable		 3q07B-1cg2A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5R_A_KANA2002_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		5 / 11 PRO A 137
ASN A 146
ILE A 121
TYR A 117
GLU A 390
 None
 1.24A 3q5rA-1cg2A:
0.0		 3q5rA-1cg2A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		5 / 11 LEU A  74
LEU A  50
THR A  46
GLY A 144
ASP A 142
 None
None
None
None
ZN  A 501 ( 4.8A)
 1.19A 3sfuC-1cg2A:
undetectable		 3sfuC-1cg2A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		5 / 7 ALA A  36
PRO A 398
TYR A 402
ARG A 400
ALA A 347
 None
 1.37A 3twpA-1cg2A:
undetectable		 3twpA-1cg2A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 7 ASN A 292
ALA A 326
PRO A 325
ALA A 367
 None
 1.10A 3twpA-1cg2A:
undetectable		 3twpA-1cg2A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		5 / 7 ALA A  36
PRO A 398
TYR A 402
ARG A 400
ALA A 347
 None
 1.26A 3twpB-1cg2A:
undetectable		 3twpB-1cg2A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 7 ASN A 292
ALA A 326
PRO A 325
ALA A 367
 None
 1.10A 3twpB-1cg2A:
undetectable		 3twpB-1cg2A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 7 ALA A  36
PRO A 398
TYR A 402
ALA A 347
 None
 1.03A 3twpC-1cg2A:
undetectable		 3twpC-1cg2A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 7 ASN A 292
ALA A 326
PRO A 325
ALA A 367
 None
 1.10A 3twpC-1cg2A:
undetectable		 3twpC-1cg2A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 7 PRO A 398
TYR A 402
ARG A 400
ALA A 347
 None
 1.08A 3twpC-1cg2A:
undetectable		 3twpC-1cg2A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 5 ALA A  36
PRO A 398
TYR A 402
ALA A 347
 None
 1.07A 3twpD-1cg2A:
0.0		 3twpD-1cg2A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 5 ASN A 292
ALA A 326
PRO A 325
ALA A 367
 None
 1.10A 3twpD-1cg2A:
0.0		 3twpD-1cg2A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_C_ACTC510_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 5 ARG A 324
THR A 361
ASP A 362
GLU A 200
 None
None
None
ZN  A 501 ( 1.9A)
 1.09A 3v5vC-1cg2A:
0.8
3v5vD-1cg2A:
0.7		 3v5vC-1cg2A:
23.95
3v5vD-1cg2A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_B_ACTB502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 5 GLU A 200
ARG A 324
THR A 361
ASP A 362
 ZN  A 501 ( 1.9A)
None
None
None
 1.16A 4e7cA-1cg2A:
0.8
4e7cB-1cg2A:
0.8		 4e7cA-1cg2A:
24.95
4e7cB-1cg2A:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 PHE A 171
ASN A 146
LEU A  77
LEU A  74
 None
 0.77A 4ejgB-1cg2A:
0.0		 4ejgB-1cg2A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 7 PHE A 171
ASN A 146
LEU A  77
LEU A  74
 None
 0.87A 4ejgC-1cg2A:
undetectable		 4ejgC-1cg2A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 7 LEU A 197
VAL A 196
PRO A 372
LYS A 339
 None
 1.02A 4lb2A-1cg2A:
0.6		 4lb2A-1cg2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PQA_A_X8ZA401_1
(SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		8 / 11 HIS A 112
ASP A 141
GLU A 175
GLU A 176
GLU A 200
GLY A 358
GLY A 359
HIS A 385
 ZN  A 501 ( 3.3A)
ZN  A 500 (-2.4A)
ZN  A 501 (-3.9A)
ZN  A 500 ( 2.0A)
ZN  A 501 ( 1.9A)
None
None
ZN  A 500 ( 3.2A)
 0.55A 4pqaA-1cg2A:
35.0		 4pqaA-1cg2A:
26.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PQA_A_X8ZA401_1
(SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		6 / 11 HIS A 112
ASP A 141
GLU A 176
GLU A 200
GLY A 360
HIS A 385
 ZN  A 501 ( 3.3A)
ZN  A 500 (-2.4A)
ZN  A 500 ( 2.0A)
ZN  A 501 ( 1.9A)
None
ZN  A 500 ( 3.2A)
 0.87A 4pqaA-1cg2A:
35.0		 4pqaA-1cg2A:
26.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		3 / 3 SER A 111
ASP A 206
ASP A 141
 None
None
ZN  A 500 (-2.4A)
 0.82A 4uckA-1cg2A:
undetectable		 4uckA-1cg2A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		5 / 12 GLY A 138
ILE A 121
LEU A 122
THR A 115
GLY A  56
 None
 1.01A 5d4uA-1cg2A:
undetectable		 5d4uA-1cg2A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		5 / 12 GLY A 138
ILE A 121
LEU A 122
THR A 115
GLY A  56
 None
 0.99A 5d4uB-1cg2A:
undetectable		 5d4uB-1cg2A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		5 / 12 GLY A 138
ILE A 121
LEU A 122
THR A 115
GLY A  56
 None
 0.98A 5d4uC-1cg2A:
undetectable		 5d4uC-1cg2A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 8 LEU A 107
TYR A 195
GLY A 412
ALA A 413
 None
 0.65A 5f1aA-1cg2A:
undetectable		 5f1aA-1cg2A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		4 / 7 LEU A 107
TYR A 195
GLY A 412
ALA A 413
 None
 0.71A 5f1aB-1cg2A:
undetectable		 5f1aB-1cg2A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 1cg2 CARBOXYPEPTIDASE G2
(Pseudomonas
sp.
RS-16) 		5 / 12 ALA A 306
VAL A 221
LEU A 283
VAL A 320
VAL A 318
 None
 1.01A 6dh0B-1cg2A:
undetectable		 6dh0B-1cg2A:
14.08