SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cgs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 1cgs IGG2B-KAPPA NC6.8
FAB (HEAVY CHAIN)
(Mus
musculus) 		4 / 6 THR H 113
LEU H 173
GLY H 176
TYR H 178
 None
 1.00A 1gtiC-1cgsH:
undetectable		 1gtiC-1cgsH:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1cgs IGG2B-KAPPA NC6.8
FAB (HEAVY CHAIN)
(Mus
musculus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.34A 1usqF-1cgsH:
0.0		 1usqF-1cgsH:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 1cgs IGG2B-KAPPA NC6.8
FAB (HEAVY CHAIN)
(Mus
musculus) 		5 / 12 ASP H  90
PHE H  64
MET H  81
PHE H  70
GLY H  66
 None
 1.29A 2fqyA-1cgsH:
undetectable		 2fqyA-1cgsH:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1cgs IGG2B-KAPPA NC6.8
FAB (HEAVY CHAIN)
(Mus
musculus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.35A 2jkjE-1cgsH:
0.0		 2jkjE-1cgsH:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1cgs IGG2B-KAPPA NC6.8
FAB (HEAVY CHAIN)
(Mus
musculus) 		5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
 None
 1.35A 2jklE-1cgsH:
undetectable		 2jklE-1cgsH:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1cgs IGG2B-KAPPA NC6.8
FAB (HEAVY CHAIN)
(Mus
musculus) 		3 / 3 VAL H 186
SER H 188
TRP H 191
 None
 0.96A 5jwaA-1cgsH:
undetectable		 5jwaA-1cgsH:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 1cgs IGG2B-KAPPA NC6.8
FAB (HEAVY CHAIN)
(Mus
musculus) 		4 / 6 ASN H  77
ALA H  24
PRO H  53
TYR H  27
 None
 1.07A 5umd2-1cgsH:
undetectable
5umdF-1cgsH:
undetectable		 5umd2-1cgsH:
17.82
5umdF-1cgsH:
16.58