SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ci0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ci0 PROTEIN (PNP
OXIDASE)
(Saccharomyces
cerevisiae) 		5 / 7 PHE A 198
VAL A 119
VAL A 121
TRP A 221
VAL A 192
 None
 1.41A 3hs6B-1ci0A:
0.0		 3hs6B-1ci0A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC608_0
(GBAA_1210 PROTEIN)		 1ci0 PROTEIN (PNP
OXIDASE)
(Saccharomyces
cerevisiae) 		4 / 5 GLU A 195
ARG A 209
ARG A 120
GLU A 122
 None
 1.42A 3tj7C-1ci0A:
undetectable		 3tj7C-1ci0A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1ci0 PROTEIN (PNP
OXIDASE)
(Saccharomyces
cerevisiae) 		3 / 4 ARG A  69
GLY A  68
GLU A  64
 None
 0.58A 4z2dB-1ci0A:
0.0
4z2dC-1ci0A:
undetectable		 4z2dB-1ci0A:
18.55
4z2dC-1ci0A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 1ci0 PROTEIN (PNP
OXIDASE)
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 117
LYS A  41
GLU A  45
 None
 0.53A 5d0yA-1ci0A:
0.0		 5d0yA-1ci0A:
20.66