SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ci5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OQ5_A_CELA701_1 (CARBONIC ANHYDRASE II)	1ci5	PROTEIN (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3(CD58)) (Homo sapiens)	5 / 12	GLU A 74 PHE A 15 VAL A 13 LEU A 67 THR A 68	None	1.15A	1oq5A-1ci5A: undetectable	1oq5A-1ci5A: 15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OQ5_A_CELA701_1 (CARBONIC ANHYDRASE II)	1ci5	PROTEIN (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3(CD58)) (Homo sapiens)	5 / 12	GLU A 76 PHE A 15 VAL A 13 LEU A 67 THR A 68	None	1.14A	1oq5A-1ci5A: undetectable	1oq5A-1ci5A: 15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R87_H_SPMH202_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	1ci5	PROTEIN (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3(CD58)) (Homo sapiens)	4 / 6	ASN A 40 GLU A 42 GLU A 39 GLU A 37	None	1.47A	4r87H-1ci5A: undetectable	4r87H-1ci5A: 19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OF1_A_SALA301_1 (SPORE COAT-ASSOCIATED PROTEIN N)	1ci5	PROTEIN (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3(CD58)) (Homo sapiens)	4 / 5	ALA A 45 VAL A 35 PHE A 43 ILE A 64	None	0.97A	5of1A-1ci5A: 0.0	5of1A-1ci5A: 23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OF1_B_SALB301_1 (SPORE COAT-ASSOCIATED PROTEIN N)	1ci5	PROTEIN (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3(CD58)) (Homo sapiens)	4 / 5	ALA A 45 VAL A 35 PHE A 43 ILE A 64	None	1.03A	5of1B-1ci5A: undetectable	5of1B-1ci5A: 23.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1OQ5_A_CELA701_1","CARBONIC ANHYDRASE II","1ci5","PROTEIN (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3(CD58))","Homo sapiens",5,"GLU A  74;PHE A  15;VAL A  13;LEU A  67;THR A  68","None","1.15A","1oq5A-1ci5A:undetectable","1oq5A-1ci5A:15.95"],["1OQ5_A_CELA701_1","CARBONIC ANHYDRASE II","1ci5","PROTEIN (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3(CD58))","Homo sapiens",5,"GLU A  76;PHE A  15;VAL A  13;LEU A  67;THR A  68","None","1.14A","1oq5A-1ci5A:undetectable","1oq5A-1ci5A:15.95"],["4R87_H_SPMH202_1","SPERMIDINE N1-ACETYLTRANSFERASE","1ci5","PROTEIN (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3(CD58))","Homo sapiens",4,"ASN A  40;GLU A  42;GLU A  39;GLU A  37","None","1.47A","4r87H-1ci5A:undetectable","4r87H-1ci5A:19.43"],["5OF1_A_SALA301_1","SPORE COAT-ASSOCIATED PROTEIN N","1ci5","PROTEIN (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3(CD58))","Homo sapiens",4,"ALA A  45;VAL A  35;PHE A  43;ILE A  64","None","0.97A","5of1A-1ci5A:0.0","5of1A-1ci5A:23.23"],["5OF1_B_SALB301_1","SPORE COAT-ASSOCIATED PROTEIN N","1ci5","PROTEIN (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3(CD58))","Homo sapiens",4,"ALA A  45;VAL A  35;PHE A  43;ILE A  64","None","1.03A","5of1B-1ci5A:undetectable","5of1B-1ci5A:23.23"]]