SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ci7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 ILE A  86
LEU A 170
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.78A 1axwA-1ci7A:
37.2		 1axwA-1ci7A:
44.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 11 ILE A  86
TRP A  87
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.71A 1axwB-1ci7A:
37.4		 1axwB-1ci7A:
44.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 11 ILE A  86
TRP A  87
LEU A 170
ASP A 202
LEU A 205
GLY A 206
TYR A 242
 CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.65A 1b02A-1ci7A:
33.6		 1b02A-1ci7A:
34.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		5 / 12 ILE A 143
LEU A 217
LEU A 192
PRO A 229
ILE A 146
 None
 1.02A 1dhjB-1ci7A:
undetectable		 1dhjB-1ci7A:
19.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_A_D16A414_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 12 PHE A  58
GLU A  65
ILE A  86
ASN A  90
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.65A 1hvyA-1ci7A:
12.5		 1hvyA-1ci7A:
60.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_A_D16A414_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 12 PHE A  58
GLU A  65
ILE A  86
TRP A  87
ASN A  90
ASP A 202
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.68A 1hvyA-1ci7A:
12.5		 1hvyA-1ci7A:
60.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_A_D16A414_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 PHE A  58
GLU A  65
ILE A  86
TRP A  87
ASN A  90
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.77A 1hvyA-1ci7A:
12.5		 1hvyA-1ci7A:
60.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 GLU A  65
ILE A  86
ASN A  90
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.69A 1hvyB-1ci7A:
43.5		 1hvyB-1ci7A:
60.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 GLU A  65
ILE A  86
TRP A  87
ASN A  90
ASP A 202
PHE A 209
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.69A 1hvyB-1ci7A:
43.5		 1hvyB-1ci7A:
60.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 GLU A  65
ILE A  86
TRP A  87
ASN A  90
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.83A 1hvyB-1ci7A:
43.5		 1hvyB-1ci7A:
60.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		10 / 11 PHE A  58
GLU A  65
ILE A  86
ASN A  90
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.73A 1hvyC-1ci7A:
12.6		 1hvyC-1ci7A:
60.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		10 / 11 PHE A  58
GLU A  65
ILE A  86
TRP A  87
ASN A  90
ASP A 202
GLY A 206
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.72A 1hvyC-1ci7A:
12.6		 1hvyC-1ci7A:
60.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 12 GLU A  65
ILE A  86
ASN A  90
LEU A 170
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.67A 1hvyD-1ci7A:
43.7		 1hvyD-1ci7A:
60.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 12 GLU A  65
ILE A  86
TRP A  87
ASN A  90
LEU A 170
ASP A 202
LEU A 205
PHE A 209
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.71A 1hvyD-1ci7A:
43.7		 1hvyD-1ci7A:
60.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 GLU A  65
ILE A  86
TRP A  87
ASN A  90
LEU A 170
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.83A 1hvyD-1ci7A:
43.7		 1hvyD-1ci7A:
60.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_A_D16A315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 9 PHE A  58
GLU A  65
ILE A  86
TRP A  87
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.58A 1i00A-1ci7A:
40.9		 1i00A-1ci7A:
61.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 9 PHE A  58
ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
ASN A 210
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
 0.63A 1i00B-1ci7A:
40.9		 1i00B-1ci7A:
61.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 9 PHE A  58
ILE A  86
TRP A  87
ASP A 202
PHE A 209
ASN A 210
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
 0.74A 1i00B-1ci7A:
40.9		 1i00B-1ci7A:
61.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 11 PHE A  58
ILE A  86
ASN A  90
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.76A 1ju6A-1ci7A:
43.3		 1ju6A-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 11 PHE A  58
ILE A  86
TRP A  87
ASN A  90
ASP A 202
LEU A 205
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.81A 1ju6A-1ci7A:
43.3		 1ju6A-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_B_LYAB315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 9 ILE A  86
ASN A  90
ASP A 202
LEU A 205
GLY A 206
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.58A 1ju6B-1ci7A:
43.3		 1ju6B-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_B_LYAB315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 9 ILE A  86
TRP A  87
ASN A  90
ASP A 202
LEU A 205
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.61A 1ju6B-1ci7A:
43.3		 1ju6B-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_B_LYAB315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		5 / 9 LYS A  55
ASN A  90
LEU A 205
TYR A 242
MET A 295
 CB3  A 768 ( 4.9A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 4.4A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 1.15A 1ju6B-1ci7A:
43.3		 1ju6B-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 10 ILE A  86
ASN A  90
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.74A 1ju6C-1ci7A:
43.3		 1ju6C-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 10 ILE A  86
TRP A  87
ASN A  90
ASP A 202
LEU A 205
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.79A 1ju6C-1ci7A:
43.3		 1ju6C-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 11 LYS A  55
PHE A  58
ASN A  90
LEU A 205
TYR A 242
MET A 295
 CB3  A 768 ( 4.9A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 4.4A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 1.12A 1ju6D-1ci7A:
43.3		 1ju6D-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 11 PHE A  58
ILE A  86
ASN A  90
ASP A 202
LEU A 205
GLY A 206
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.58A 1ju6D-1ci7A:
43.3		 1ju6D-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 11 PHE A  58
ILE A  86
TRP A  87
ASN A  90
ASP A 202
LEU A 205
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.65A 1ju6D-1ci7A:
43.3		 1ju6D-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_A_LYAA315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 10 ILE A  86
ASN A  90
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.83A 1jujA-1ci7A:
42.4		 1jujA-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_A_LYAA315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 10 ILE A  86
TRP A  87
ASN A  90
ASP A 202
LEU A 205
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.89A 1jujA-1ci7A:
42.4		 1jujA-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_B_LYAB315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 10 ILE A  86
ASN A  90
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.83A 1jujB-1ci7A:
42.3		 1jujB-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_B_LYAB315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 10 ILE A  86
TRP A  87
ASN A  90
ASP A 202
LEU A 205
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.89A 1jujB-1ci7A:
42.3		 1jujB-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 10 ILE A  86
ASN A  90
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.83A 1jujC-1ci7A:
42.3		 1jujC-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 10 ILE A  86
TRP A  87
ASN A  90
ASP A 202
LEU A 205
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.89A 1jujC-1ci7A:
42.3		 1jujC-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 10 ILE A  86
ASN A  90
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.83A 1jujD-1ci7A:
42.3		 1jujD-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 10 ILE A  86
TRP A  87
ASN A  90
ASP A 202
LEU A 205
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.89A 1jujD-1ci7A:
42.3		 1jujD-1ci7A:
57.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 8 PHE A  58
ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.64A 1rtsA-1ci7A:
41.0		 1rtsA-1ci7A:
58.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 7 ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.57A 1rtsB-1ci7A:
41.7		 1rtsB-1ci7A:
58.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 ILE A  86
TRP A  87
LEU A 170
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 1.00A 1tlsA-1ci7A:
37.3		 1tlsA-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 ILE A  86
TRP A  87
LEU A 170
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.97A 1tlsB-1ci7A:
37.6		 1tlsB-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TSN_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 ILE A  86
TRP A  87
LEU A 170
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.94A 1tsnA-1ci7A:
37.5		 1tsnA-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 12 GLU A  65
TRP A  87
LEU A 170
ASP A 202
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.82A 2kceA-1ci7A:
37.4		 2kceA-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 12 TRP A  87
LEU A 170
ASP A 202
GLY A 206
PHE A 209
TYR A 242
 None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 1.12A 2kceA-1ci7A:
37.4		 2kceA-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 TRP A  87
LEU A 170
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.75A 2kceB-1ci7A:
37.6		 2kceB-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 7 ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.58A 2tsrA-1ci7A:
41.0		 2tsrA-1ci7A:
58.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 8 ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.55A 2tsrB-1ci7A:
41.6		 2tsrB-1ci7A:
58.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		5 / 8 ILE A  86
TRP A  87
ASP A 202
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.79A 2tsrB-1ci7A:
41.6		 2tsrB-1ci7A:
58.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 10 PHE A  58
GLU A  65
ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.51A 2tsrC-1ci7A:
41.0		 2tsrC-1ci7A:
58.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 10 PHE A  58
GLU A  65
ILE A  86
TRP A  87
ASP A 202
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.64A 2tsrC-1ci7A:
41.0		 2tsrC-1ci7A:
58.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_D_D16D609_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 9 PHE A  58
ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.58A 2tsrD-1ci7A:
41.2		 2tsrD-1ci7A:
58.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_D_D16D609_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 9 PHE A  58
ILE A  86
ASP A 202
LEU A 205
PHE A 209
TYR A 242
THR A 290
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
None
 0.79A 2tsrD-1ci7A:
41.2		 2tsrD-1ci7A:
58.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_D_D16D609_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 9 PHE A  58
ILE A  86
TRP A  87
ASP A 202
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.69A 2tsrD-1ci7A:
41.2		 2tsrD-1ci7A:
58.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 12 GLU A  65
ILE A  86
TRP A  87
LEU A 170
ASP A 202
LEU A 205
GLY A 206
TYR A 242
MET A 295
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.80A 3k2hA-1ci7A:
0.0		 3k2hA-1ci7A:
32.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 12 ILE A  86
TRP A  87
LEU A 170
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 1.04A 3k2hA-1ci7A:
0.0		 3k2hA-1ci7A:
32.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 12 GLU A  65
ILE A  86
TRP A  87
LEU A 170
ASP A 202
LEU A 205
GLY A 206
TYR A 242
MET A 295
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.79A 3k2hB-1ci7A:
12.6		 3k2hB-1ci7A:
32.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 ILE A  86
LEU A 170
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 1.01A 3k2hB-1ci7A:
12.6		 3k2hB-1ci7A:
32.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 GLU A  65
ILE A  86
ASN A  90
ASP A 202
LEU A 205
GLY A 206
TYR A 242
MET A 295
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.68A 3nrrA-1ci7A:
14.5		 3nrrA-1ci7A:
32.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 GLU A  65
ILE A  86
TRP A  87
ASN A  90
ASP A 202
TYR A 242
MET A 295
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.57A 3nrrA-1ci7A:
14.5		 3nrrA-1ci7A:
32.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 ILE A  86
ASN A  90
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.94A 3nrrA-1ci7A:
14.5		 3nrrA-1ci7A:
32.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 ILE A  86
TRP A  87
ASN A  90
ASP A 202
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.96A 3nrrA-1ci7A:
14.5		 3nrrA-1ci7A:
32.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NRR_B_D16B530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 GLU A  65
ILE A  86
ASN A  90
ASP A 202
LEU A 205
GLY A 206
TYR A 242
MET A 295
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.69A 3nrrB-1ci7A:
14.3		 3nrrB-1ci7A:
32.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NRR_B_D16B530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 GLU A  65
ILE A  86
TRP A  87
ASN A  90
ASP A 202
TYR A 242
MET A 295
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.57A 3nrrB-1ci7A:
14.3		 3nrrB-1ci7A:
32.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NRR_B_D16B530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 ILE A  86
ASN A  90
ASP A 202
GLY A 206
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.92A 3nrrB-1ci7A:
14.3		 3nrrB-1ci7A:
32.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NRR_B_D16B530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 ILE A  86
TRP A  87
ASN A  90
ASP A 202
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.98A 3nrrB-1ci7A:
14.3		 3nrrB-1ci7A:
32.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 12 ILE A  86
LEU A 205
GLY A 206
PHE A 209
ASN A 210
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
 1.01A 3uwlB-1ci7A:
37.4		 3uwlB-1ci7A:
44.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 ILE A  86
TRP A  87
LEU A 170
HIS A 174
LEU A 205
GLY A 206
ASN A 210
TYR A 242
 CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
None
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
 0.81A 3uwlB-1ci7A:
37.4		 3uwlB-1ci7A:
44.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		5 / 12 LEU A 205
GLY A 206
PHE A 209
ASN A 210
TYR A 242
 CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
 0.95A 3uwlD-1ci7A:
36.5		 3uwlD-1ci7A:
44.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 TRP A  87
LEU A 170
HIS A 174
LEU A 205
GLY A 206
ASN A 210
TYR A 242
 None
UMP  A 767 (-4.7A)
None
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
 0.82A 3uwlD-1ci7A:
36.5		 3uwlD-1ci7A:
44.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 12 PHE A  58
ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
ASN A 210
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.66A 4eb4A-1ci7A:
43.0		 4eb4A-1ci7A:
58.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 PHE A  58
ILE A  86
TRP A  87
ASP A 202
PHE A 209
ASN A 210
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.64A 4eb4A-1ci7A:
43.0		 4eb4A-1ci7A:
58.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 12 PHE A  58
ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
ASN A 210
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.68A 4eb4B-1ci7A:
42.9		 4eb4B-1ci7A:
58.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 12 PHE A  58
ILE A  86
TRP A  87
ASP A 202
GLY A 206
PHE A 209
ASN A 210
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.68A 4eb4B-1ci7A:
42.9		 4eb4B-1ci7A:
58.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 9 PHE A  58
ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
ASN A 210
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
 0.67A 4eb4C-1ci7A:
40.4		 4eb4C-1ci7A:
58.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 10 PHE A  58
ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
ASN A 210
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
 0.60A 4eb4D-1ci7A:
41.5		 4eb4D-1ci7A:
58.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 10 PHE A  58
ILE A  86
TRP A  87
ASP A 202
GLY A 206
PHE A 209
ASN A 210
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
 0.65A 4eb4D-1ci7A:
41.5		 4eb4D-1ci7A:
58.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 11 ILE A  86
LEU A 170
ASP A 202
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.83A 4fogA-1ci7A:
36.3		 4fogA-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 11 ILE A  86
TRP A  87
LEU A 170
ASP A 202
GLY A 206
TYR A 242
 CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.47A 4fogA-1ci7A:
36.3		 4fogA-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		5 / 11 ILE A  86
ASP A 202
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.90A 4fogC-1ci7A:
37.0		 4fogC-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 11 ILE A  86
TRP A  87
LEU A 170
ASP A 202
GLY A 206
TYR A 242
 CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.71A 4fogC-1ci7A:
37.0		 4fogC-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 11 ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.78A 4fogD-1ci7A:
37.8		 4fogD-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 11 ILE A  86
TRP A  87
LEU A 170
ASP A 202
LEU A 205
GLY A 206
TYR A 242
 CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.70A 4fogD-1ci7A:
37.8		 4fogD-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 GLU A  65
ILE A  86
TRP A  87
LEU A 170
ASP A 202
LEU A 205
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.78A 4foxA-1ci7A:
36.5		 4foxA-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 ILE A  86
TRP A  87
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 1.01A 4foxA-1ci7A:
36.5		 4foxA-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 GLU A  65
ILE A  86
LEU A 170
ASP A 202
LEU A 205
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.70A 4foxB-1ci7A:
36.6		 4foxB-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 GLU A  65
ILE A  86
TRP A  87
LEU A 170
ASP A 202
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.65A 4foxB-1ci7A:
36.6		 4foxB-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 12 ILE A  86
LEU A 170
ASP A 202
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 1.05A 4foxB-1ci7A:
36.6		 4foxB-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 11 GLU A  65
LEU A 170
ASP A 202
LEU A 205
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.84A 4foxC-1ci7A:
36.3		 4foxC-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 11 GLU A  65
TRP A  87
LEU A 170
ASP A 202
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.82A 4foxC-1ci7A:
36.3		 4foxC-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 11 LEU A 170
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 1.07A 4foxC-1ci7A:
36.3		 4foxC-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 11 TRP A  87
LEU A 170
ASP A 202
GLY A 206
PHE A 209
TYR A 242
 None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 1.10A 4foxC-1ci7A:
36.3		 4foxC-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 GLU A  65
ILE A  86
TRP A  87
ASP A 202
LEU A 205
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.74A 4foxD-1ci7A:
37.5		 4foxD-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 ILE A  86
TRP A  87
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.98A 4foxD-1ci7A:
37.5		 4foxD-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 GLU A  65
ILE A  86
TRP A  87
ASP A 202
LEU A 205
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.67A 4foxE-1ci7A:
36.5		 4foxE-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 12 ILE A  86
TRP A  87
ASP A 202
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 1.02A 4foxE-1ci7A:
36.5		 4foxE-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 11 GLU A  65
ILE A  86
TRP A  87
LEU A 170
ASP A 202
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.78A 4foxF-1ci7A:
36.6		 4foxF-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 11 ILE A  86
TRP A  87
ASP A 202
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 1.01A 4foxF-1ci7A:
36.6		 4foxF-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 GLU A  65
ILE A  86
TRP A  87
LEU A 170
ASP A 202
LEU A 205
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.73A 4foxG-1ci7A:
36.5		 4foxG-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 ILE A  86
TRP A  87
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.98A 4foxG-1ci7A:
36.5		 4foxG-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_H_D16H301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 11 GLU A  65
ILE A  86
TRP A  87
ASP A 202
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.76A 4foxH-1ci7A:
36.3		 4foxH-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_H_D16H301_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 11 ILE A  86
TRP A  87
ASP A 202
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.98A 4foxH-1ci7A:
36.3		 4foxH-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 GLU A  65
ILE A  86
TRP A  87
ASP A 202
LEU A 205
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.72A 4fqsA-1ci7A:
37.5		 4fqsA-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 12 ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.87A 4fqsA-1ci7A:
37.5		 4fqsA-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 GLU A  65
ILE A  86
TRP A  87
ASP A 202
LEU A 205
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.73A 4fqsB-1ci7A:
37.4		 4fqsB-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 12 ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.88A 4fqsB-1ci7A:
37.4		 4fqsB-1ci7A:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 7 ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.66A 4iqqA-1ci7A:
41.2		 4iqqA-1ci7A:
53.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		5 / 7 ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.71A 4iqqB-1ci7A:
40.6		 4iqqB-1ci7A:
53.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		4 / 7 ILE A  86
ASP A 202
GLY A 206
PHE A 209
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
 0.59A 4iqqB-1ci7A:
40.6		 4iqqB-1ci7A:
53.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		5 / 7 ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.61A 4iqqC-1ci7A:
40.6		 4iqqC-1ci7A:
53.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		4 / 7 ILE A  86
ASP A 202
GLY A 206
PHE A 209
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
 0.55A 4iqqC-1ci7A:
40.6		 4iqqC-1ci7A:
53.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 8 ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.63A 4iqqD-1ci7A:
40.0		 4iqqD-1ci7A:
53.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		4 / 9 CYH A 177
HIS A 174
ILE A 221
MET A 220
 None
 1.25A 4jvlA-1ci7A:
0.0		 4jvlA-1ci7A:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 11 PHE A  58
ILE A  86
ASN A  90
LEU A 170
ASP A 202
LEU A 205
GLY A 206
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.72A 5fctA-1ci7A:
43.9		 5fctA-1ci7A:
58.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 11 PHE A  58
ILE A  86
TRP A  87
ASN A  90
LEU A 170
ASP A 202
LEU A 205
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.76A 5fctA-1ci7A:
43.9		 5fctA-1ci7A:
58.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 12 LYS A  55
VAL A  57
PHE A  58
LEU A 205
TYR A 242
MET A 293
 CB3  A 768 ( 4.9A)
CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.4A)
CB3  A 768 ( 4.7A)
None
 1.14A 5fctB-1ci7A:
44.0		 5fctB-1ci7A:
58.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 12 VAL A  57
PHE A  58
ILE A  86
LEU A 170
CYH A 173
LEU A 205
TYR A 242
MET A 293
MET A 295
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
UMP  A 767 (-4.7A)
UMP  A 767 (-1.9A)
CB3  A 768 ( 4.4A)
CB3  A 768 ( 4.7A)
None
CB3  A 768 (-3.8A)
 0.68A 5fctB-1ci7A:
44.0		 5fctB-1ci7A:
58.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 12 VAL A  57
PHE A  58
ILE A  86
TRP A  87
LEU A 170
LEU A 205
TYR A 242
MET A 293
MET A 295
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 4.4A)
CB3  A 768 ( 4.7A)
None
CB3  A 768 (-3.8A)
 0.68A 5fctB-1ci7A:
44.0		 5fctB-1ci7A:
58.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		3 / 3 ASN A  90
ASP A 202
GLY A 206
 CB3  A 768 (-3.8A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
 0.63A 5fctB-1ci7A:
44.0		 5fctB-1ci7A:
58.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H3A_A_D16A401_1
(ORF70)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 7 PHE A  58
ILE A  86
ASP A 202
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.50A 5h3aA-1ci7A:
40.8		 5h3aA-1ci7A:
60.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H3A_B_D16B401_1
(ORF70)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 7 PHE A  58
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.59A 5h3aB-1ci7A:
12.3		 5h3aB-1ci7A:
60.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H3A_B_D16B401_1
(ORF70)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 7 PHE A  58
ILE A  86
ASP A 202
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.43A 5h3aB-1ci7A:
12.3		 5h3aB-1ci7A:
60.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 12 GLU A  65
ILE A  86
LEU A 170
LEU A 205
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.76A 5j7wC-1ci7A:
37.3		 5j7wC-1ci7A:
44.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 12 GLU A  65
LEU A 170
ASP A 202
LEU A 205
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.80A 5j7wC-1ci7A:
37.3		 5j7wC-1ci7A:
44.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 GLU A  65
ILE A  86
TRP A  87
LEU A 170
ASP A 202
LEU A 205
GLY A 206
TYR A 242
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.78A 5j7wD-1ci7A:
36.9		 5j7wD-1ci7A:
44.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 12 ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.89A 5j7wD-1ci7A:
36.9		 5j7wD-1ci7A:
44.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		5 / 12 PHE A  49
LEU A 216
ALA A 212
PHE A 209
ILE A  63
 None
None
None
CB3  A 768 (-3.6A)
None
 1.12A 5ljeA-1ci7A:
undetectable		 5ljeA-1ci7A:
17.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 7 ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.68A 5nooA-1ci7A:
41.4		 5nooA-1ci7A:
53.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		5 / 7 ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.73A 5nooB-1ci7A:
41.0		 5nooB-1ci7A:
53.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		5 / 7 ILE A  86
ASP A 202
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.62A 5nooB-1ci7A:
41.0		 5nooB-1ci7A:
53.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		5 / 6 ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.75A 5nooC-1ci7A:
12.5		 5nooC-1ci7A:
53.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 8 ARG A  56
ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 None
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.84A 5nooD-1ci7A:
12.5		 5nooD-1ci7A:
53.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 GLU A  65
ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.82A 5x5qB-1ci7A:
42.6		 5x5qB-1ci7A:
61.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 GLU A  65
ILE A  86
ASP A 202
LEU A 205
PHE A 209
TYR A 242
THR A 290
MET A 295
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
None
CB3  A 768 (-3.8A)
 0.84A 5x5qB-1ci7A:
42.6		 5x5qB-1ci7A:
61.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 GLU A  65
ILE A  86
ASP A 202
PHE A 209
TYR A 242
THR A 290
MET A 293
MET A 295
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
None
None
CB3  A 768 (-3.8A)
 0.81A 5x5qB-1ci7A:
42.6		 5x5qB-1ci7A:
61.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 12 GLU A  65
ILE A  86
TRP A  87
ASP A 202
GLY A 206
PHE A 209
TYR A 242
MET A 293
MET A 295
 CB3  A 768 ( 4.0A)
CB3  A 768 (-3.6A)
None
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
None
CB3  A 768 (-3.8A)
 0.84A 5x5qB-1ci7A:
42.6		 5x5qB-1ci7A:
61.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 7 PHE A  58
ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.64A 5x5qC-1ci7A:
40.7		 5x5qC-1ci7A:
61.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 8 LYS A  55
PHE A  58
ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 ( 4.9A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.75A 5x5qD-1ci7A:
12.5		 5x5qD-1ci7A:
61.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		6 / 6 PHE A  58
ILE A  86
ASP A 202
LEU A 205
GLY A 206
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.63A 5x5qE-1ci7A:
41.1		 5x5qE-1ci7A:
61.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 8 PHE A  58
ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.61A 5x5qF-1ci7A:
41.1		 5x5qF-1ci7A:
61.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 PHE A  58
ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
ASN A 210
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
 0.65A 5x66A-1ci7A:
42.7
5x66B-1ci7A:
12.7		 5x66A-1ci7A:
61.28
5x66B-1ci7A:
61.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 PHE A  58
ILE A  86
LEU A 205
PHE A 209
ASN A 210
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.4A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.88A 5x66A-1ci7A:
42.7
5x66B-1ci7A:
12.7		 5x66A-1ci7A:
61.28
5x66B-1ci7A:
61.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 9 ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
ASN A 210
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
 0.56A 5x66C-1ci7A:
42.5		 5x66C-1ci7A:
61.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		5 / 9 ILE A  86
PHE A 209
ASN A 210
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.80A 5x66C-1ci7A:
42.5		 5x66C-1ci7A:
61.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 10 PHE A  58
ILE A  86
ASP A 202
GLY A 206
PHE A 209
ASN A 210
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.64A 5x66D-1ci7A:
42.7		 5x66D-1ci7A:
61.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 LYS A  55
PHE A  58
ILE A  86
LEU A 205
PHE A 209
TYR A 242
MET A 295
 CB3  A 768 ( 4.9A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.4A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 1.16A 5x66F-1ci7A:
42.8		 5x66F-1ci7A:
61.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 12 PHE A  58
ILE A  86
ASP A 202
LEU A 205
GLY A 206
PHE A 209
TYR A 242
THR A 290
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
None
CB3  A 768 (-3.8A)
 0.73A 5x66F-1ci7A:
42.8		 5x66F-1ci7A:
61.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		4 / 5 ILE A  99
SER A  98
ALA A  89
LEU A 109
 None
 0.96A 6dwnA-1ci7A:
0.0		 6dwnA-1ci7A:
14.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		5 / 12 ILE A  86
LEU A 205
GLY A 206
PHE A 209
TYR A 242
 CB3  A 768 (-3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
CB3  A 768 ( 4.7A)
 0.89A 6qxsB-1ci7A:
36.4		 6qxsB-1ci7A:
44.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 ILE A  86
TRP A  87
LEU A 170
LEU A 205
GLY A 206
ASN A 210
TYR A 242
 CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
 0.79A 6qxsB-1ci7A:
36.4		 6qxsB-1ci7A:
44.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_D_FOZD403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 ILE A  86
TRP A  87
LEU A 170
ASP A 202
LEU A 205
GLY A 206
ASN A 210
 CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
UMP  A 767 ( 2.6A)
 0.74A 6qxsD-1ci7A:
36.3		 6qxsD-1ci7A:
44.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		7 / 12 ILE A  86
TRP A  87
LEU A 170
HIS A 174
LEU A 205
GLY A 206
TYR A 242
 CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
None
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 ( 4.7A)
 0.79A 6qyaB-1ci7A:
36.0		 6qyaB-1ci7A:
44.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		8 / 12 ILE A  86
TRP A  87
LEU A 170
HIS A 174
LEU A 205
GLY A 206
ASN A 210
TYR A 242
 CB3  A 768 (-3.6A)
None
UMP  A 767 (-4.7A)
None
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
 0.74A 6qyaD-1ci7A:
35.9		 6qyaD-1ci7A:
44.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_A_FFOA403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		10 / 12 PHE A  58
ASN A  90
LEU A 170
ASP A 202
LEU A 205
GLY A 206
PHE A 209
ASN A 210
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 1.05A 6r2eA-1ci7A:
43.6		 6r2eA-1ci7A:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_A_FFOA403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		10 / 12 PHE A  58
ILE A  86
ASN A  90
LEU A 170
LEU A 205
GLY A 206
PHE A 209
ASN A 210
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 1.03A 6r2eA-1ci7A:
43.6		 6r2eA-1ci7A:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_A_FFOA403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		10 / 12 PHE A  58
ILE A  86
TRP A  87
ASN A  90
LEU A 170
LEU A 205
GLY A 206
ASN A 210
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.84A 6r2eA-1ci7A:
43.6		 6r2eA-1ci7A:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_A_FFOA403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		10 / 12 PHE A  58
TRP A  87
ASN A  90
LEU A 170
ASP A 202
LEU A 205
GLY A 206
ASN A 210
TYR A 242
MET A 295
 CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
UMP  A 767 ( 2.6A)
CB3  A 768 ( 4.7A)
CB3  A 768 (-3.8A)
 0.86A 6r2eA-1ci7A:
43.6		 6r2eA-1ci7A:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_B_FFOB403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		10 / 10 PHE A  58
ILE A  86
TRP A  87
ASN A  90
LEU A 170
ASP A 202
LEU A 205
GLY A 206
ASN A 210
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
UMP  A 767 ( 2.6A)
CB3  A 768 (-3.8A)
 0.76A 6r2eB-1ci7A:
43.3		 6r2eB-1ci7A:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_C_FFOC404_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		10 / 10 PHE A  58
ILE A  86
TRP A  87
ASN A  90
LEU A 170
ASP A 202
LEU A 205
GLY A 206
ASN A 210
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
UMP  A 767 ( 2.6A)
CB3  A 768 (-3.8A)
 0.84A 6r2eC-1ci7A:
43.6		 6r2eC-1ci7A:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_D_FFOD403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 10 PHE A  58
ILE A  86
TRP A  87
ASN A  90
LEU A 170
LEU A 205
GLY A 206
ASN A 210
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
UMP  A 767 ( 2.6A)
CB3  A 768 (-3.8A)
 0.74A 6r2eD-1ci7A:
43.4		 6r2eD-1ci7A:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_D_FFOD403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 10 PHE A  58
TRP A  87
ASN A  90
LEU A 170
ASP A 202
LEU A 205
GLY A 206
ASN A 210
MET A 295
 CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
UMP  A 767 ( 2.6A)
CB3  A 768 (-3.8A)
 0.77A 6r2eD-1ci7A:
43.4		 6r2eD-1ci7A:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_E_FFOE403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 12 PHE A  58
ILE A  86
ASN A  90
LEU A 170
LEU A 205
GLY A 206
PHE A 209
ASN A 210
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 (-3.8A)
 1.03A 6r2eE-1ci7A:
43.3		 6r2eE-1ci7A:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_E_FFOE403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		10 / 12 PHE A  58
ILE A  86
TRP A  87
ASN A  90
TYR A 113
LEU A 170
LEU A 205
GLY A 206
ASN A 210
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
UMP  A 767 ( 2.6A)
CB3  A 768 (-3.8A)
 0.76A 6r2eE-1ci7A:
43.3		 6r2eE-1ci7A:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		10 / 11 PHE A  58
ILE A  86
TRP A  87
ASN A  90
LEU A 170
ASP A 202
LEU A 205
GLY A 206
ASN A 210
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
UMP  A 767 ( 2.6A)
CB3  A 768 (-3.8A)
 0.82A 6r2eF-1ci7A:
43.5		 6r2eF-1ci7A:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_G_FFOG403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		10 / 11 PHE A  58
ILE A  86
ASN A  90
LEU A 170
ASP A 202
LEU A 205
GLY A 206
PHE A 209
ASN A 210
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
CB3  A 768 (-3.6A)
UMP  A 767 ( 2.6A)
CB3  A 768 (-3.8A)
 1.03A 6r2eG-1ci7A:
43.4		 6r2eG-1ci7A:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_G_FFOG403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		9 / 11 PHE A  58
ILE A  86
TRP A  87
ASN A  90
LEU A 170
ASP A 202
LEU A 205
ASN A 210
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 ( 2.6A)
CB3  A 768 (-3.8A)
 0.78A 6r2eG-1ci7A:
43.4		 6r2eG-1ci7A:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_H_FFOH403_0
(THYMIDYLATE SYNTHASE)		 1ci7 PROTEIN (THYMIDYLATE
SYNTHASE)
(Pneumocystis
carinii) 		11 / 12 PHE A  58
ILE A  86
TRP A  87
ASN A  90
TYR A 113
LEU A 170
ASP A 202
LEU A 205
GLY A 206
ASN A 210
MET A 295
 CB3  A 768 (-3.6A)
CB3  A 768 (-3.6A)
None
CB3  A 768 (-3.8A)
None
UMP  A 767 (-4.7A)
CB3  A 768 ( 3.6A)
CB3  A 768 ( 4.4A)
UMP  A 767 (-3.7A)
UMP  A 767 ( 2.6A)
CB3  A 768 (-3.8A)
 0.88A 6r2eH-1ci7A:
43.6		 6r2eH-1ci7A:
55.56