SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cic'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1cic PROTEIN (IG HEAVY
CHAIN V REGIONS)
(Mus
musculus) 		4 / 7 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.82A 1usqA-1cicB:
0.0		 1usqA-1cicB:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1cic PROTEIN (IG HEAVY
CHAIN V REGIONS)
(Mus
musculus) 		4 / 6 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.83A 1usqB-1cicB:
0.0		 1usqB-1cicB:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1cic PROTEIN (IG HEAVY
CHAIN V REGIONS)
(Mus
musculus) 		4 / 6 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.82A 1usqC-1cicB:
0.0		 1usqC-1cicB:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1cic PROTEIN (IG HEAVY
CHAIN V REGIONS)
(Mus
musculus) 		4 / 6 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.83A 1usqD-1cicB:
0.0		 1usqD-1cicB:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1cic PROTEIN (IG HEAVY
CHAIN V REGIONS)
(Mus
musculus) 		4 / 6 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.81A 1usqE-1cicB:
undetectable		 1usqE-1cicB:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1cic PROTEIN (IG HEAVY
CHAIN V REGIONS)
(Mus
musculus) 		4 / 7 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.81A 1usqF-1cicB:
undetectable		 1usqF-1cicB:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1cic PROTEIN (IG HEAVY
CHAIN V REGIONS)
(Mus
musculus) 		4 / 7 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.88A 2jklC-1cicB:
undetectable		 2jklC-1cicB:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1cic PROTEIN (IG HEAVY
CHAIN V REGIONS)
(Mus
musculus) 		4 / 7 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.87A 2jklD-1cicB:
undetectable		 2jklD-1cicB:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 1cic PROTEIN (IG HEAVY
CHAIN V REGIONS)
(Mus
musculus) 		3 / 3 SER B 165
SER B 164
HIS B 168
 None
 0.79A 3mzeA-1cicB:
0.0		 3mzeA-1cicB:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1cic PROTEIN (IG HEAVY
CHAIN V REGIONS)
(Mus
musculus) 		3 / 3 ARG B  98
HIS B 106
TYR B  32
 None
 1.18A 4fu8A-1cicB:
0.0		 4fu8A-1cicB:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1cic PROTEIN (IG HEAVY
CHAIN V REGIONS)
(Mus
musculus) 		3 / 3 ARG B  98
HIS B 106
TYR B  32
 None
 1.19A 4fu9A-1cicB:
0.0		 4fu9A-1cicB:
21.37