SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cid'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_1
(DIHYDROFOLATE
REDUCTASE)		 1cid T CELL SURFACE
GLYCOPROTEIN CD4
(Rattus
norvegicus) 		5 / 12 GLN A 135
LEU A 133
VAL A 151
LEU A 117
ILE A 175
 None
 0.97A 1df7A-1cidA:
undetectable		 1df7A-1cidA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 1cid T CELL SURFACE
GLYCOPROTEIN CD4
(Rattus
norvegicus) 		4 / 6 PRO A 127
LYS A 128
MET A 129
GLU A 168
 None
 1.27A 1qhyA-1cidA:
undetectable		 1qhyA-1cidA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 1cid T CELL SURFACE
GLYCOPROTEIN CD4
(Rattus
norvegicus) 		5 / 11 LEU A  66
LEU A  72
SER A  25
LEU A  48
LEU A  89
 None
 0.94A 2xn5A-1cidA:
0.0		 2xn5A-1cidA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1cid T CELL SURFACE
GLYCOPROTEIN CD4
(Rattus
norvegicus) 		5 / 12 GLU A 101
LEU A 163
SER A   2
GLY A  85
LEU A 104
 None
 1.32A 3j6pB-1cidA:
undetectable		 3j6pB-1cidA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 1cid T CELL SURFACE
GLYCOPROTEIN CD4
(Rattus
norvegicus) 		5 / 12 LEU A  74
THR A  73
ALA A  13
ALA A   5
LEU A 104
 None
 1.07A 3p5nA-1cidA:
undetectable		 3p5nA-1cidA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 1cid T CELL SURFACE
GLYCOPROTEIN CD4
(Rattus
norvegicus) 		5 / 12 LEU A  74
THR A  73
ALA A  13
ALA A   5
LEU A 104
 None
 1.07A 3p5nB-1cidA:
undetectable		 3p5nB-1cidA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 1cid T CELL SURFACE
GLYCOPROTEIN CD4
(Rattus
norvegicus) 		5 / 10 LEU A  66
LEU A  72
SER A  25
LEU A  48
LEU A  89
 None
 1.05A 4yiaA-1cidA:
0.0		 4yiaA-1cidA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1cid T CELL SURFACE
GLYCOPROTEIN CD4
(Rattus
norvegicus) 		3 / 3 THR A 118
PRO A 112
ASP A 113
 None
 0.80A 5l8dB-1cidA:
undetectable		 5l8dB-1cidA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1cid T CELL SURFACE
GLYCOPROTEIN CD4
(Rattus
norvegicus) 		3 / 3 THR A 118
PRO A 112
ASP A 113
 None
 0.80A 5mwuB-1cidA:
undetectable		 5mwuB-1cidA:
17.56