SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cij'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		4 / 8 HIS A 289
GLY A 171
LEU A 263
ASP A 260
 None
 0.79A 1aegA-1cijA:
undetectable		 1aegA-1cijA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		4 / 8 LEU A  15
ARG A  64
TYR A  18
SER A  60
 None
 1.13A 1hk3A-1cijA:
undetectable		 1hk3A-1cijA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		5 / 8 ALA A 149
ASP A 124
ILE A 146
GLY A 257
PRO A 281
 None
BR  A 401 ( 4.8A)
None
None
None
 1.44A 1sh9A-1cijA:
undetectable		 1sh9A-1cijA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		5 / 12 GLY A 127
GLY A 130
LEU A 120
LEU A 133
LEU A 109
 None
 0.98A 1ya4C-1cijA:
11.8		 1ya4C-1cijA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		4 / 8 TYR A  63
PRO A 134
PHE A 243
TRP A 244
 None
 1.48A 3bjwD-1cijA:
undetectable		 3bjwD-1cijA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		5 / 11 ALA A 149
ASP A 124
GLY A 264
PRO A 281
ILE A 146
 None
BR  A 401 ( 4.8A)
None
None
None
 0.94A 3ekxA-1cijA:
undetectable		 3ekxA-1cijA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		4 / 8 ALA A 149
ASP A 124
GLY A 264
PRO A 281
 None
BR  A 401 ( 4.8A)
None
None
 0.86A 3el9A-1cijA:
undetectable		 3el9A-1cijA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		5 / 11 ALA A 149
ASP A 124
GLY A 264
PRO A 281
ILE A 146
 None
BR  A 401 ( 4.8A)
None
None
None
 0.95A 3em4A-1cijA:
undetectable		 3em4A-1cijA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		5 / 10 ALA A 149
LEU A 131
ALA A 240
ILE A 241
PHE A 161
 None
 1.02A 3fl9F-1cijA:
undetectable		 3fl9F-1cijA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		4 / 7 TYR A  18
GLU A  41
LEU A  15
TRP A  59
 None
 1.34A 3k8mB-1cijA:
undetectable		 3k8mB-1cijA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		4 / 7 PHE A  82
GLY A  55
PHE A 222
PHE A 101
 None
 1.07A 3ko0D-1cijA:
undetectable
3ko0E-1cijA:
0.3		 3ko0D-1cijA:
15.46
3ko0E-1cijA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		5 / 11 ALA A 149
ASP A 124
GLY A 264
PRO A 281
ILE A 146
 None
BR  A 401 ( 4.8A)
None
None
None
 0.99A 3oxxD-1cijA:
undetectable		 3oxxD-1cijA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		5 / 12 ALA A 108
LEU A 106
LEU A  53
LEU A 120
LEU A 115
 None
 1.19A 3r9cA-1cijA:
0.0		 3r9cA-1cijA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		5 / 12 GLY A 257
GLY A 264
ASP A 260
PHE A 290
GLU A 283
 None
 1.34A 3t7sA-1cijA:
undetectable		 3t7sA-1cijA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		5 / 12 GLY A 257
GLY A 264
ASP A 260
PHE A 290
GLU A 283
 None
 1.27A 3t7sB-1cijA:
undetectable		 3t7sB-1cijA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		5 / 12 GLY A 257
GLY A 264
ASP A 260
PHE A 290
GLU A 283
 None
 1.29A 3t7sD-1cijA:
undetectable		 3t7sD-1cijA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		5 / 6 PHE A  83
ALA A  36
GLY A  33
PRO A  32
LEU A  28
 None
 1.46A 4dubB-1cijA:
0.0		 4dubB-1cijA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		5 / 12 MET A  66
TYR A  63
GLN A 123
GLY A 257
VAL A 121
 None
 1.33A 5g6sB-1cijA:
undetectable
5g6sC-1cijA:
undetectable		 5g6sB-1cijA:
22.51
5g6sC-1cijA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		4 / 5 LEU A 107
PHE A 105
LEU A 133
PHE A 141
 None
 1.13A 5iy5P-1cijA:
undetectable
5iy5W-1cijA:
0.0		 5iy5P-1cijA:
21.50
5iy5W-1cijA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		4 / 6 ILE A 118
GLY A  42
ASN A  43
ILE A  78
 None
 0.87A 5j4nB-1cijA:
0.0		 5j4nB-1cijA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MTH_B_ACTB302_0
(ANTIBODY FAB HEAVY
CHAIN
ANTIBODY FAB LIGHT
CHAIN)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		4 / 5 GLU A 293
TYR A 206
TYR A  63
ARG A  64
 None
 1.33A 5mthA-1cijA:
undetectable
5mthB-1cijA:
undetectable		 5mthA-1cijA:
18.93
5mthB-1cijA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MTH_H_ACTH304_0
(ANTIBODY FAB HEAVY
CHAIN
ANTIBODY FAB LIGHT
CHAIN)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		4 / 5 GLU A 293
TYR A 206
TYR A  63
ARG A  64
 None
 1.29A 5mthH-1cijA:
0.0
5mthL-1cijA:
0.0		 5mthH-1cijA:
18.93
5mthL-1cijA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		5 / 8 ARG A   6
LYS A  90
ALA A   4
VAL A  92
SER A 214
 None
 1.40A 5v0vA-1cijA:
undetectable		 5v0vA-1cijA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		4 / 5 LEU A 107
PHE A 105
LEU A 133
PHE A 141
 None
 1.12A 5xdxC-1cijA:
undetectable
5xdxJ-1cijA:
0.0		 5xdxC-1cijA:
21.50
5xdxJ-1cijA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1cij PROTEIN (HALOALKANE
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		4 / 5 LEU A 107
PHE A 105
LEU A 133
PHE A 141
 None
 1.14A 5xdxP-1cijA:
undetectable
5xdxW-1cijA:
0.0		 5xdxP-1cijA:
21.50
5xdxW-1cijA:
11.18