SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cj2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		3 / 3 THR A 217
THR A 192
PRO A 194
 None
 0.73A 1a7yB-1cj2A:
undetectable		 1a7yB-1cj2A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 12 LEU A 325
ILE A 155
GLY A 157
ALA A 156
LEU A 309
 None
 1.00A 1cqeA-1cj2A:
0.0		 1cqeA-1cj2A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 12 LEU A 325
ILE A 155
GLY A 157
ALA A 156
LEU A 309
 None
 0.99A 1cqeB-1cj2A:
0.0		 1cqeB-1cj2A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.35A 1ereA-1cj2A:
undetectable		 1ereA-1cj2A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.38A 1ereB-1cj2A:
undetectable		 1ereB-1cj2A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.35A 1ereC-1cj2A:
undetectable		 1ereC-1cj2A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.37A 1ereD-1cj2A:
undetectable		 1ereD-1cj2A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 8 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.36A 1ereE-1cj2A:
undetectable		 1ereE-1cj2A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 8 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.35A 1ereF-1cj2A:
undetectable		 1ereF-1cj2A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 12 GLU A  49
LEU A  48
LEU A 301
ARG A 335
ILE A 290
 None
 0.97A 1errA-1cj2A:
undetectable		 1errA-1cj2A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_B_ESTB600_1
(OESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.39A 1gwrB-1cj2A:
undetectable		 1gwrB-1cj2A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		3 / 3 THR A 192
PRO A 194
THR A 217
 None
 0.81A 1i3wG-1cj2A:
undetectable		 1i3wG-1cj2A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		6 / 12 VAL A 349
LEU A 350
LEU A 372
LEU A 368
LEU A 378
PHE A 342
 None
 1.21A 1mx1D-1cj2A:
undetectable		 1mx1D-1cj2A:
22.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		10 / 10 GLY A  46
VAL A  47
TRP A 185
LEU A 199
TYR A 201
LEU A 210
SER A 212
ARG A 214
TYR A 222
ALA A 296
 PHB  A 396 ( 3.6A)
FAD  A 395 (-4.1A)
None
None
PHB  A 396 ( 4.6A)
None
PHB  A 396 ( 2.7A)
PHB  A 396 ( 3.0A)
PHB  A 396 (-4.6A)
FAD  A 395 (-3.6A)
 0.25A 1pbcA-1cj2A:
67.3		 1pbcA-1cj2A:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBF_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		6 / 9 TRP A 185
LEU A 199
TYR A 201
SER A 212
ARG A 214
ARG A 220
 None
None
PHB  A 396 ( 4.6A)
PHB  A 396 ( 2.7A)
PHB  A 396 ( 3.0A)
None
 0.71A 1pbfA-1cj2A:
67.3		 1pbfA-1cj2A:
99.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBF_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		8 / 9 VAL A  47
TRP A 185
LEU A 199
TYR A 201
LEU A 210
SER A 212
ARG A 214
ALA A 296
 FAD  A 395 (-4.1A)
None
None
PHB  A 396 ( 4.6A)
None
PHB  A 396 ( 2.7A)
PHB  A 396 ( 3.0A)
FAD  A 395 (-3.6A)
 0.33A 1pbfA-1cj2A:
67.3		 1pbfA-1cj2A:
99.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_B_ESTB2_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.45A 1pcgB-1cj2A:
undetectable		 1pcgB-1cj2A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		3 / 3 THR A 217
THR A 192
PRO A 194
 None
 0.70A 1qfiB-1cj2A:
undetectable		 1qfiB-1cj2A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		3 / 3 THR A 192
PRO A 194
THR A 217
 None
 0.84A 1unjF-1cj2A:
undetectable		 1unjF-1cj2A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		3 / 3 THR A 192
PRO A 194
THR A 217
 None
 0.85A 1unjL-1cj2A:
undetectable		 1unjL-1cj2A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		3 / 3 THR A 192
PRO A 194
THR A 217
 None
 0.85A 1unmE-1cj2A:
undetectable		 1unmE-1cj2A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		4 / 8 LEU A 372
PHE A 342
MET A 346
SER A 348
 None
 1.00A 1wrlC-1cj2A:
undetectable
1wrlD-1cj2A:
undetectable		 1wrlC-1cj2A:
12.36
1wrlD-1cj2A:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		3 / 3 THR A 192
PRO A 194
THR A 217
 None
 0.79A 209dC-1cj2A:
undetectable		 209dC-1cj2A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 12 GLU A  49
LEU A  48
LEU A 301
ARG A 335
ILE A 290
 None
 1.05A 2jfaA-1cj2A:
undetectable		 2jfaA-1cj2A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 12 GLU A  49
LEU A  48
LEU A 301
ARG A 335
ILE A 290
 None
 1.08A 2qxsA-1cj2A:
undetectable		 2qxsA-1cj2A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		4 / 4 SER A  13
GLY A  14
GLY A 285
GLY A 160
 FAD  A 395 (-3.0A)
None
FAD  A 395 (-3.5A)
FAD  A 395 (-3.5A)
 0.91A 3bogB-1cj2A:
0.0
3bogD-1cj2A:
0.0		 3bogB-1cj2A:
undetectable
3bogD-1cj2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 12 ALA A  10
GLY A   9
SER A  13
MET A 110
LEU A  40
 None
FAD  A 395 (-3.4A)
FAD  A 395 (-3.0A)
None
None
 1.04A 3bxoA-1cj2A:
undetectable		 3bxoA-1cj2A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 12 GLY A 157
ASP A 159
ILE A 164
LEU A 281
LEU A 132
 None
FAD  A 395 (-4.9A)
FAD  A 395 (-4.0A)
None
None
 0.99A 3cjtC-1cj2A:
3.5		 3cjtC-1cj2A:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_B_DESB800_1
(ESTROGEN RECEPTOR
ALPHA)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.42A 3erdB-1cj2A:
undetectable		 3erdB-1cj2A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 12 LEU A 281
GLY A 279
LEU A 132
ARG A 280
ASP A 151
 None
 0.99A 3gwvA-1cj2A:
0.0		 3gwvA-1cj2A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 12 LEU A 281
GLY A 279
LEU A 132
ILE A 155
ASP A 151
 None
 1.10A 3gwwA-1cj2A:
0.0		 3gwwA-1cj2A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 12 LEU A 325
ILE A 155
GLY A 157
ALA A 156
LEU A 309
 None
 1.05A 3n8xB-1cj2A:
0.0		 3n8xB-1cj2A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 11 ALA A   6
VAL A 139
GLY A   9
ALA A  10
LEU A 129
 None
None
FAD  A 395 (-3.4A)
None
None
 0.87A 3sm2B-1cj2A:
undetectable		 3sm2B-1cj2A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 12 LEU A 309
ILE A  26
ILE A   8
ASP A 153
LEU A 281
 None
None
FAD  A 395 (-4.8A)
None
None
 0.91A 3uj6A-1cj2A:
undetectable		 3uj6A-1cj2A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_B_ESTB600_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.39A 3uudB-1cj2A:
0.0		 3uudB-1cj2A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 12 TYR A 390
LEU A  48
VAL A 105
LEU A 109
VAL A  61
 None
 0.91A 3w68A-1cj2A:
undetectable		 3w68A-1cj2A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 12 TYR A 390
LEU A  48
VAL A 105
LEU A 109
VAL A  61
 None
 0.90A 3w68D-1cj2A:
0.4		 3w68D-1cj2A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC392_1
(TETX2 PROTEIN)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 12 GLU A 383
PHE A 342
VAL A  75
ILE A  86
GLU A  49
 None
 1.17A 4a99A-1cj2A:
29.1
4a99C-1cj2A:
29.0		 4a99A-1cj2A:
23.11
4a99C-1cj2A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		4 / 7 GLU A  49
ARG A 335
ASP A 305
ALA A 303
 None
 1.00A 4zz8A-1cj2A:
undetectable		 4zz8A-1cj2A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 9 ALA A 156
ASP A 159
GLY A  14
LEU A  17
LEU A 309
 None
FAD  A 395 (-4.9A)
None
None
None
 1.23A 5dqfA-1cj2A:
0.2		 5dqfA-1cj2A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 9 ALA A 284
LEU A  16
GLY A  14
LEU A  17
LEU A 309
 None
 1.17A 5dqfA-1cj2A:
0.2		 5dqfA-1cj2A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
GLY A  14
 None
 1.27A 5dx3A-1cj2A:
0.0		 5dx3A-1cj2A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.39A 5dx3A-1cj2A:
0.0		 5dx3A-1cj2A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.43A 5dx3B-1cj2A:
0.0		 5dx3B-1cj2A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
GLY A  14
 None
 1.33A 5dxbA-1cj2A:
0.0		 5dxbA-1cj2A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.40A 5hyrA-1cj2A:
0.0		 5hyrA-1cj2A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 11 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.40A 5hyrB-1cj2A:
0.0		 5hyrB-1cj2A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		4 / 6 ILE A 381
VAL A 349
TYR A 201
TRP A 345
 None
None
PHB  A 396 ( 4.6A)
None
 0.90A 5jwaH-1cj2A:
4.5		 5jwaH-1cj2A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		4 / 4 GLN A   4
THR A   3
LEU A  17
LEU A  21
 None
 1.26A 5m5kB-1cj2A:
3.7		 5m5kB-1cj2A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 11 ILE A 164
GLY A 163
GLY A 160
LEU A  31
VAL A 127
 FAD  A 395 (-4.0A)
FAD  A 395 (-3.6A)
FAD  A 395 (-3.5A)
None
FAD  A 395 (-4.6A)
 0.91A 5twjD-1cj2A:
undetectable		 5twjD-1cj2A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		4 / 7 SER A 168
ILE A 164
LEU A 129
LEU A 132
 None
FAD  A 395 (-4.0A)
None
None
 0.95A 5u4sA-1cj2A:
undetectable		 5u4sA-1cj2A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		4 / 5 ARG A 166
PHE A 282
LEU A 281
LEU A 333
 None
 1.18A 5veuH-1cj2A:
undetectable		 5veuH-1cj2A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGD_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.40A 5wgdA-1cj2A:
0.0		 5wgdA-1cj2A:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
GLY A  14
 None
 1.31A 5wgqA-1cj2A:
undetectable		 5wgqA-1cj2A:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.42A 6cbzB-1cj2A:
undetectable		 6cbzB-1cj2A:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		4 / 7 ILE A  26
GLN A   4
VAL A   5
ALA A 156
 None
 0.88A 6cduC-1cj2A:
undetectable
6cduD-1cj2A:
undetectable		 6cduC-1cj2A:
22.52
6cduD-1cj2A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		4 / 8 ILE A  26
GLN A   4
VAL A   5
ALA A 156
 None
 0.87A 6cduD-1cj2A:
undetectable
6cduE-1cj2A:
0.0		 6cduD-1cj2A:
22.52
6cduE-1cj2A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		4 / 7 ALA A 156
ILE A  26
GLN A   4
VAL A   5
 None
 0.96A 6cduF-1cj2A:
undetectable
6cduJ-1cj2A:
undetectable		 6cduF-1cj2A:
22.52
6cduJ-1cj2A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)
(Pseudomonas
fluorescens) 		4 / 8 LEU A 210
LEU A 199
GLY A 298
TYR A 385
 None
None
FAD  A 395 (-3.4A)
None
 0.95A 6ce2A-1cj2A:
undetectable		 6ce2A-1cj2A:
13.72