SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cjw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_B_IBPB1701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	1cjw	PROTEIN (SEROTONIN N-ACETYLTRANSFERASE) (Ovis aries)	6 / 11	VAL A 48 SER A 81 LEU A 74 ILE A 94 ALA A 123 LEU A 65	None None None None COT A 400 (-4.1A) None	1.14A	1eqgB-1cjwA: 0.0	1eqgB-1cjwA: 15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LBD_A_9CRA424_1 (RETINOIC ACID RECEPTOR GAMMA)	1cjw	PROTEIN (SEROTONIN N-ACETYLTRANSFERASE) (Ovis aries)	5 / 12	ALA A 55 LEU A 124 SER A 60 GLY A 136 ILE A 51	COT A 400 ( 4.0A) COT A 400 (-4.5A) COT A 400 (-3.4A) COT A 400 (-3.5A) None	1.07A	3lbdA-1cjwA: 0.0	3lbdA-1cjwA: 21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LTW_A_HLZA300_1 (ARYLAMINE N-ACETYLTRANSFERASE NAT)	1cjw	PROTEIN (SEROTONIN N-ACETYLTRANSFERASE) (Ovis aries)	4 / 6	PHE A 171 TYR A 168 VAL A 126 PHE A 167	None COT A 400 (-4.9A) COT A 400 (-4.1A) COT A 400 (-4.2A)	1.34A	3ltwA-1cjwA: undetectable	3ltwA-1cjwA: 21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XXI_A_LSNA501_2 (CYTOCHROME P450 2C9)	1cjw	PROTEIN (SEROTONIN N-ACETYLTRANSFERASE) (Ovis aries)	4 / 4	PHE A 85 LEU A 124 LEU A 82 VAL A 126	None COT A 400 (-4.5A) None COT A 400 (-4.1A)	1.28A	5xxiA-1cjwA: 0.0	5xxiA-1cjwA: 16.82

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EQG_B_IBPB1701_1","PROSTAGLANDIN H2 SYNTHASE-1","1cjw","PROTEIN (SEROTONIN N-ACETYLTRANSFERASE)","Ovis aries",6,"VAL A  48;SER A  81;LEU A  74;ILE A  94;ALA A 123;LEU A  65","None;None;None;None;COT A 400 (-4.1A);None","1.14A","1eqgB-1cjwA:0.0","1eqgB-1cjwA:15.03"],["3LBD_A_9CRA424_1","RETINOIC ACID RECEPTOR GAMMA","1cjw","PROTEIN (SEROTONIN N-ACETYLTRANSFERASE)","Ovis aries",5,"ALA A  55;LEU A 124;SER A  60;GLY A 136;ILE A  51","COT A 400 ( 4.0A);COT A 400 (-4.5A);COT A 400 (-3.4A);COT A 400 (-3.5A);None","1.07A","3lbdA-1cjwA:0.0","3lbdA-1cjwA:21.62"],["3LTW_A_HLZA300_1","ARYLAMINE N-ACETYLTRANSFERASE NAT","1cjw","PROTEIN (SEROTONIN N-ACETYLTRANSFERASE)","Ovis aries",4,"PHE A 171;TYR A 168;VAL A 126;PHE A 167","None;COT A 400 (-4.9A);COT A 400 (-4.1A);COT A 400 (-4.2A)","1.34A","3ltwA-1cjwA:undetectable","3ltwA-1cjwA:21.00"],["5XXI_A_LSNA501_2","CYTOCHROME P450 2C9","1cjw","PROTEIN (SEROTONIN N-ACETYLTRANSFERASE)","Ovis aries",4,"PHE A  85;LEU A 124;LEU A  82;VAL A 126","None;COT A 400 (-4.5A);None;COT A 400 (-4.1A)","1.28A","5xxiA-1cjwA:0.0","5xxiA-1cjwA:16.82"]]