SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ckr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 1ckr HEAT SHOCK SUBSTRATE
BINDING DOMAIN OF
HSC-70
(Rattus
norvegicus) 		4 / 7 GLU A 520
MET A 408
MET A 447
ALA A 446
 None
 1.30A 1linA-1ckrA:
undetectable		 1linA-1ckrA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1ckr HEAT SHOCK SUBSTRATE
BINDING DOMAIN OF
HSC-70
(Rattus
norvegicus) 		5 / 11 ASP A 531
ASN A 537
VAL A 474
THR A 409
ILE A 401
 None
 1.33A 3n23A-1ckrA:
0.0		 3n23A-1ckrA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB203_1
(CALMODULIN)		 1ckr HEAT SHOCK SUBSTRATE
BINDING DOMAIN OF
HSC-70
(Rattus
norvegicus) 		4 / 7 LEU A 397
MET A 515
ALA A 519
MET A 408
 None
 0.88A 4rjdB-1ckrA:
undetectable		 4rjdB-1ckrA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 1ckr HEAT SHOCK SUBSTRATE
BINDING DOMAIN OF
HSC-70
(Rattus
norvegicus) 		4 / 5 SER A 534
SER A 535
SER A 538
SER A 430
 None
 1.35A 5hswA-1ckrA:
undetectable		 5hswA-1ckrA:
15.16