SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cl7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 1cl7 PROTEIN (IGG1
ANTIBODY 1696
(VARIABLE HEAVY
CHAIN))
PROTEIN (IGG1
ANTIBODY 1696
(CONSTANT HEAVY
CHAIN))
(Mus
musculus;
Mus
musculus) 		4 / 4 THR H 116
PRO H 118
THR H 117
PRO I 154
 None
 1.35A 1dsdC-1cl7H:
undetectable		 1dsdC-1cl7H:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 1cl7 PROTEIN (IGG1
ANTIBODY 1696
(VARIABLE HEAVY
CHAIN))
PROTEIN (IGG1
ANTIBODY 1696
(CONSTANT HEAVY
CHAIN))
(Mus
musculus;
Mus
musculus) 		4 / 4 THR H 117
PRO I 154
THR H 116
PRO H 118
 None
 1.25A 1dsdC-1cl7H:
undetectable		 1dsdC-1cl7H:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 1cl7 PROTEIN (IGG1
ANTIBODY 1696
(VARIABLE HEAVY
CHAIN))
PROTEIN (IGG1
ANTIBODY 1696
(CONSTANT HEAVY
CHAIN))
(Mus
musculus;
Mus
musculus) 		4 / 4 THR H 116
PRO H 118
THR H 117
PRO I 154
 None
 1.35A 1dsdC-1cl7H:
undetectable		 1dsdC-1cl7H:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 1cl7 PROTEIN (IGG1
ANTIBODY 1696
(VARIABLE HEAVY
CHAIN))
PROTEIN (IGG1
ANTIBODY 1696
(CONSTANT HEAVY
CHAIN))
(Mus
musculus;
Mus
musculus) 		4 / 4 THR H 117
PRO I 154
THR H 116
PRO H 118
 None
 1.25A 1dsdC-1cl7H:
undetectable		 1dsdC-1cl7H:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 1cl7 PROTEIN (IGG1
ANTIBODY 1696
(VARIABLE HEAVY
CHAIN))
(Mus
musculus) 		4 / 7 GLN H   6
THR H 107
SER H   7
TYR H  90
 None
 1.35A 1eiiA-1cl7H:
0.0		 1eiiA-1cl7H:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 1cl7 PROTEIN (IGG1
ANTIBODY 1696
(CONSTANT HEAVY
CHAIN))
(Mus
musculus) 		5 / 11 LEU I 145
VAL I 170
GLY I 164
VAL I 190
VAL I 188
 None
 1.05A 2nnpB-1cl7I:
undetectable		 2nnpB-1cl7I:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1cl7 PROTEIN (IGG1
ANTIBODY 1696
(CONSTANT HEAVY
CHAIN))
(Mus
musculus) 		5 / 12 VAL I 170
VAL I 188
SER I 186
ASN I 203
ASN I 162
 None
 1.45A 2y03A-1cl7I:
undetectable		 2y03A-1cl7I:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1cl7 PROTEIN (IGG1
ANTIBODY 1696
(CONSTANT HEAVY
CHAIN))
(Mus
musculus) 		5 / 12 VAL I 170
VAL I 188
SER I 186
ASN I 203
ASN I 162
 None
 1.46A 2y03B-1cl7I:
undetectable		 2y03B-1cl7I:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 1cl7 PROTEIN (IGG1
ANTIBODY 1696
(VARIABLE HEAVY
CHAIN))
(Mus
musculus) 		3 / 3 LYS H  12
LYS H  19
VAL H  18
 None
 1.10A 3brfA-1cl7H:
1.2		 3brfA-1cl7H:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 1cl7 PROTEIN (IGG1
ANTIBODY 1696
(CONSTANT HEAVY
CHAIN))
(Mus
musculus) 		5 / 10 VAL I 170
VAL I 188
SER I 186
ASN I 203
ASN I 162
 None
 1.43A 4ldoA-1cl7I:
undetectable		 4ldoA-1cl7I:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 1cl7 PROTEIN (IGG1
ANTIBODY 1696
(CONSTANT HEAVY
CHAIN))
(Mus
musculus) 		5 / 12 VAL I 170
VAL I 188
SER I 186
ASN I 203
ASN I 162
 None
 1.44A 6h7mB-1cl7I:
undetectable		 6h7mB-1cl7I:
18.68