SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1clw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		3 / 3 VAL A 240
VAL A 236
TRP A 391
 None
 0.89A 1av2C-1clwA:
undetectable
1av2D-1clwA:
undetectable		 1av2C-1clwA:
2.32
1av2D-1clwA:
2.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		3 / 3 TRP A 391
ALA A 436
VAL A 390
 None
 0.88A 1c4dA-1clwA:
undetectable
1c4dB-1clwA:
undetectable		 1c4dA-1clwA:
2.32
1c4dB-1clwA:
2.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		4 / 6 PHE A 336
GLY A 348
SER A 384
PHE A 381
 None
 1.14A 1icuA-1clwA:
0.0
1icuB-1clwA:
0.0		 1icuA-1clwA:
18.05
1icuB-1clwA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		4 / 6 SER A 384
PHE A 381
PHE A 336
GLY A 348
 None
 1.15A 1icuC-1clwA:
0.0
1icuD-1clwA:
0.0		 1icuC-1clwA:
18.05
1icuD-1clwA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		4 / 5 PHE A 336
GLY A 348
SER A 384
PHE A 381
 None
 1.22A 1icuC-1clwA:
0.0
1icuD-1clwA:
undetectable		 1icuC-1clwA:
18.05
1icuD-1clwA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		4 / 5 PHE A 336
GLY A 348
SER A 384
PHE A 381
 None
 1.22A 1icvA-1clwA:
0.0
1icvB-1clwA:
0.0		 1icvA-1clwA:
18.05
1icvB-1clwA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 8 ILE A 516
LEU A 501
ILE A 526
VAL A 530
ILE A 535
 None
 1.47A 1linA-1clwA:
undetectable		 1linA-1clwA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		3 / 3 ILE A 180
ASP A 159
PHE A 160
 None
 0.63A 1uwjB-1clwA:
0.0		 1uwjB-1clwA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		3 / 3 VAL A 240
VAL A 236
TRP A 391
 None
 0.90A 1w5uC-1clwA:
undetectable
1w5uD-1clwA:
undetectable		 1w5uC-1clwA:
2.32
1w5uD-1clwA:
2.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		3 / 3 LYS A 241
ASP A 395
ASP A 444
 None
 1.02A 2br4A-1clwA:
undetectable		 2br4A-1clwA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		3 / 3 VAL A 236
TRP A 391
VAL A 240
 None
 0.94A 2izqA-1clwA:
undetectable
2izqB-1clwA:
undetectable		 2izqA-1clwA:
2.32
2izqB-1clwA:
2.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		4 / 5 SER A 586
GLY A 582
ASP A 602
ASP A 556
 None
 0.99A 2oxtB-1clwA:
undetectable		 2oxtB-1clwA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		3 / 3 GLY A 462
GLY A 438
GLY A 440
 None
 0.40A 3bogC-1clwA:
0.2		 3bogC-1clwA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 8 LEU A 503
ALA A 463
VAL A 455
GLY A 460
ILE A 477
 None
 1.20A 3ekpA-1clwA:
undetectable		 3ekpA-1clwA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 10 ILE A 492
ILE A 490
GLY A 440
VAL A 450
LEU A 466
 None
 1.28A 3em0A-1clwA:
2.9		 3em0A-1clwA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 12 HIS A 420
LEU A 419
GLY A 367
LEU A 337
ASP A 395
 None
 1.05A 3i5uA-1clwA:
undetectable		 3i5uA-1clwA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 12 HIS A 420
LEU A 419
GLY A 367
LEU A 337
ASP A 395
 None
 1.18A 3i5uA-1clwA:
undetectable		 3i5uA-1clwA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 12 HIS A 420
LEU A 419
GLY A 367
LEU A 337
ASP A 395
 None
 1.06A 3i5uB-1clwA:
undetectable		 3i5uB-1clwA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 12 HIS A 420
LEU A 419
GLY A 367
LEU A 337
ASP A 395
 None
 1.19A 3i5uB-1clwA:
undetectable		 3i5uB-1clwA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 10 LEU A 144
LEU A 133
VAL A 158
ILE A 190
LEU A 262
 None
 1.20A 3jw5B-1clwA:
undetectable		 3jw5B-1clwA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		3 / 3 PHE A 381
TYR A 320
LEU A 432
 None
 0.80A 3keeB-1clwA:
0.0		 3keeB-1clwA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		3 / 3 VAL A 240
VAL A 236
TRP A 391
 None
 0.92A 3l8lC-1clwA:
undetectable
3l8lD-1clwA:
undetectable		 3l8lC-1clwA:
2.32
3l8lD-1clwA:
2.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 7 ILE A 350
GLY A 351
SER A 384
PHE A 394
LEU A 431
 None
 1.46A 3v7pA-1clwA:
0.9		 3v7pA-1clwA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRI_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 10 LEU A 647
SER A 646
TRP A 640
ASP A 623
TYR A 639
 None
 1.41A 4driB-1clwA:
undetectable		 4driB-1clwA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 12 ALA A 275
LEU A 262
PHE A 173
LEU A 133
ILE A 146
 None
 1.05A 4nx6A-1clwA:
undetectable		 4nx6A-1clwA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 12 ALA A 275
LEU A 262
PHE A 173
LEU A 133
ILE A 146
 None
 1.10A 4nx7A-1clwA:
undetectable		 4nx7A-1clwA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		4 / 7 PHE A 160
ASP A 159
GLN A 134
ILE A 180
 None
 1.08A 4pcuA-1clwA:
undetectable		 4pcuA-1clwA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 12 ALA A 275
LEU A 262
PHE A 173
LEU A 133
ILE A 146
 None
 1.09A 4pstA-1clwA:
undetectable		 4pstA-1clwA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		4 / 8 THR A 482
ILE A 477
LEU A 437
VAL A 386
 None
 0.97A 4r38B-1clwA:
2.1		 4r38B-1clwA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		3 / 3 SER A 521
ASP A 531
ASP A 517
 None
 0.80A 4uckA-1clwA:
undetectable		 4uckA-1clwA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZAU_A_YY3A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 8 LEU A 144
GLY A 143
VAL A 125
ALA A 136
LEU A 133
 None
 1.11A 4zauA-1clwA:
undetectable		 4zauA-1clwA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		3 / 3 GLY A 397
VAL A 450
MET A 448
 None
 0.63A 5ycpA-1clwA:
undetectable		 5ycpA-1clwA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 12 TYR A 320
GLY A 341
GLY A 348
ASN A 340
ASP A 346
 None
 1.34A 5yn6A-1clwA:
0.0		 5yn6A-1clwA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 12 ALA A 275
LEU A 262
PHE A 173
LEU A 133
ILE A 146
 None
 0.99A 5z6jA-1clwA:
undetectable		 5z6jA-1clwA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 12 MET A 279
GLY A 301
GLY A 304
ALA A 331
ILE A 258
 None
 0.97A 6b3aA-1clwA:
undetectable		 6b3aA-1clwA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 1clw TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 12 MET A 279
GLY A 301
GLY A 304
ALA A 331
ILE A 258
 None
 1.00A 6b3bA-1clwA:
undetectable		 6b3bA-1clwA:
21.02