SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cly'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 8 THR H 110
GLY H   9
MET H  89
PRO H 214
 None
 0.83A 1rxcB-1clyH:
undetectable		 1rxcB-1clyH:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 8 THR H 110
GLY H   9
MET H  89
PRO H 214
 None
 0.85A 1rxcE-1clyH:
undetectable		 1rxcE-1clyH:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 8 THR H 110
GLY H   9
MET H  89
PRO H 214
 None
 0.81A 1rxcI-1clyH:
undetectable		 1rxcI-1clyH:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 8 THR H 110
GLY H   9
MET H  89
PRO H 214
 None
 0.83A 1rxcK-1clyH:
undetectable		 1rxcK-1clyH:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 5 TYR H  91
MET H  89
THR H 107
LEU H 108
 None
 1.43A 2eimW-1clyH:
0.0		 2eimW-1clyH:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		5 / 12 VAL H 171
VAL H 191
SER H 189
ASN H 209
ASN H 162
 None
 1.44A 2y03A-1clyH:
undetectable		 2y03A-1clyH:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 5 TYR H  91
MET H  89
THR H 107
LEU H 108
 None
 1.45A 3ag1J-1clyH:
undetectable		 3ag1J-1clyH:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 5 TYR H  91
MET H  89
THR H 107
LEU H 108
 None
 1.43A 3ag2J-1clyH:
undetectable		 3ag2J-1clyH:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 5 TYR H  91
MET H  89
THR H 107
LEU H 108
 None
 1.43A 3ag4J-1clyH:
undetectable		 3ag4J-1clyH:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 8 THR H 110
GLY H   9
MET H  89
PRO H 214
 None
 0.85A 4e1vA-1clyH:
undetectable		 4e1vA-1clyH:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 8 THR H 110
GLY H   9
MET H  89
PRO H 214
 None
 0.82A 4e1vC-1clyH:
undetectable		 4e1vC-1clyH:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 8 THR H 110
GLY H   9
MET H  89
PRO H 214
 None
 0.85A 4e1vD-1clyH:
undetectable		 4e1vD-1clyH:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 8 THR H 110
GLY H   9
MET H  89
PRO H 214
 None
 0.83A 4e1vE-1clyH:
undetectable		 4e1vE-1clyH:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 8 THR H 110
GLY H   9
MET H  89
PRO H 214
 None
 0.81A 4e1vG-1clyH:
undetectable		 4e1vG-1clyH:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 8 THR H 110
GLY H   9
MET H  89
PRO H 214
 None
 0.83A 4e1vH-1clyH:
undetectable		 4e1vH-1clyH:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 5 TYR H  90
LEU H  80
LEU H  82
ARG H  66
 None
 1.15A 4em2A-1clyH:
undetectable		 4em2A-1clyH:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		5 / 10 PHE H 122
GLY H 118
THR H 217
VAL H 210
VAL H 219
 None
 1.15A 4jx1B-1clyH:
undetectable		 4jx1B-1clyH:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		4 / 5 TYR H  91
MET H  89
THR H 107
LEU H 108
 None
 1.43A 5z86J-1clyH:
0.0		 5z86J-1clyH:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 1cly IGG FAB (HUMAN IGG1,
KAPPA)
(Homo
sapiens) 		3 / 3 PRO H 194
SER H 196
SER H 197
 None
 0.27A 6bpyA-1clyH:
undetectable		 6bpyA-1clyH:
20.70