SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1clz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1clz IGG FAB (IGG3,
KAPPA)
(Mus
musculus) 		4 / 5 TYR H  91
MET H  89
THR H 107
LEU H 108
 None
 1.42A 2eimW-1clzH:
0.0		 2eimW-1clzH:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1clz IGG FAB (IGG3,
KAPPA)
(Mus
musculus) 		4 / 5 TYR H  91
MET H  89
THR H 107
LEU H 108
 None
 1.41A 3ag2J-1clzH:
0.0		 3ag2J-1clzH:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1clz IGG FAB (IGG3,
KAPPA)
(Mus
musculus) 		4 / 5 TYR H  91
MET H  89
THR H 107
LEU H 108
 None
 1.42A 3ag4J-1clzH:
0.0		 3ag4J-1clzH:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 1clz IGG FAB (IGG3,
KAPPA)
(Mus
musculus) 		5 / 10 VAL H 171
VAL H 191
SER H 189
ASN H 209
ASN H 162
 None
 1.50A 4ldoA-1clzH:
0.0		 4ldoA-1clzH:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1clz IGG FAB (IGG3,
KAPPA)
(Mus
musculus) 		4 / 5 TYR H  91
MET H  89
THR H 107
LEU H 108
 None
 1.41A 5z86J-1clzH:
0.0		 5z86J-1clzH:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 1clz IGG FAB (IGG3,
KAPPA)
(Mus
musculus) 		3 / 3 PRO H 194
SER H 195
SER H 196
 None
 0.64A 6bpyA-1clzH:
0.4		 6bpyA-1clzH:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 1clz IGG FAB (IGG3,
KAPPA)
(Mus
musculus) 		5 / 12 VAL H 171
VAL H 191
SER H 189
ASN H 209
ASN H 162
 None
 1.45A 6h7mB-1clzH:
undetectable		 6h7mB-1clzH:
18.31